N-Heterocyclic Carbene Catalyzed Nucleophilic Substitution Reaction for Construction of Benzopyrones and Benzofuranones

Jinmei He,† Jiyue Zheng,† Jian Liu,† Xuegong She,*†‡ and Xinfu Pan*†
Department of Chemistry, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, P. R. China, and State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, P. R. China
Org. Lett., 2006, 8 (20), pp 4637–4640
DOI: 10.1021/ol061924f
Publication Date (Web): August 31, 2006
Copyright © 2006 American Chemical Society
†

 Lanzhou University.

,
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

,
‡

 Chinese Academy of Sciences.

, shexg@lzu.edu.cn

Abstract

Abstract Image

N-Heterocyclic carbene as an efficient organic catalyst was employed to catalyze an intramolecular nucleophilic substitution reaction. When R2 was a phenyl group, the cyclization process underwent isomerization, leading to generation of benzofuranone.

View: Full Text HTML | Hi-Res PDF

Tools

History

  • Published In Issue September 28, 2006
  • Received August 3, 2006

Recommend & Share

Related Content

Other ACS content by these authors: