Palladium- and Copper-Catalyzed 1,4-Additions of Organozinc Compounds to Conjugated Aldehydes

James A. Marshall,* Martin Herold, Hilary S. Eidam, and Patrick Eidam
Department of Chemistry, University of Virginia, P.O. Box 400319, Charlottesville, Virginia 22904
Org. Lett., 2006, 8 (24), pp 5505–5508
DOI: 10.1021/ol062154a
Publication Date (Web): October 31, 2006
Copyright © 2006 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, jam5x@virginia.edu

Abstract

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Conjugated aldehydes undergo smooth Pd(OAc)2·PPh3- or Me2CuCNLi2-catalyzed 1,4-addition of dialkylzinc reagents.

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History

  • Published In Issue November 23, 2006
  • Received August 31, 2006

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