Letter
General and Highly Efficient Synthesis of 2-Alkylideneazetidines and β-Lactams via Copper-Catalyzed Intramolecular N-Vinylation
In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.
Abstract

N-Tosyl-3-halo-3-butenylamines underwent efficient Ullmann-type coupling with the catalysis of CuI/N,N‘-dimethylethylenediamine to afford 2-alkylideneazetidines, which could be readily converted to the corresponding β-lactams by oxidation with O3.
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History
- Published In Issue November 09, 2006
- Received September 15, 2006
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