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Letter

Allylpalladium Umpolung in the Three-Component Coupling Synthesis of Homoallylic Amines

Supporting Info

Chad D. Hopkins and Helena C. Malinakova*

Department of Chemistry, University of Kansas, 1251 Wescoe Hall Drive, Lawrence, Kansas 66045-7582

Org. Lett., 2006, 8 (26), pp 5971–5974

DOI: 10.1021/ol0624528

Publication Date (Web): December 1, 2006

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, hmalina@ku.edu

Abstract

Homoallylic amines and α-amino esters were prepared via a Pd(II)-catalyzed coupling of boronic acids and 1,2-nonadiene with ethyl iminoacetate or aliphatic, aromatic, and heteroaromatic imines. The allylpalladium umpolung was induced by a Pd(OAc)₂ catalyst with commercial phosphine ligands.

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Published In Issue December 21, 2006
Received October 5, 2006

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Letter

Allylpalladium Umpolung in the Three-Component Coupling Synthesis of Homoallylic Amines

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Catalytic Carbon−Carbon σ Bond Activation: An Intramolecular Carbo-Acylation Reaction with Acylquinolines

Design and Stereoselective Preparation of a New Class of Chiral Olefin Metathesis Catalysts and Application to Enantioselective Synthesis of Quebrachamine: Catalyst Development Inspired by Natural Product Synthesis

aza-Baylis−Hillman Reaction

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