Catalytic Oxidation of Imines Based on Methyltrioxorhenium/Urea Hydrogen Peroxide:  A Mild and Easy Chemo- and Regioselective Entry to Nitrones

Gianluca Soldaini, Francesca Cardona, and Andrea Goti*
Dipartimento di Chimica Organica Ugo Schiff, Laboratorio di Progettazione, Sintesi e Studio di Eterocicli Biologicamente Attivi (HeteroBioLab) and Consorzio INSTM, Universit di Firenze, via della Lastruccia 13, I-50019 Sesto Fiorentino (Firenze), Italy
Org. Lett., 2007, 9 (3), pp 473–476
DOI: 10.1021/ol062862w
Publication Date (Web): January 4, 2007
Copyright © 2007 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, andrea.goti@unifi.it

Abstract

Abstract Image

The first successful catalytic oxidation procedure for the chemoselective conversion of imines to nitrones is reported. The reaction is general, high yielding, and user and environmentally friendly, and furnishes a solution to the yet unanswered issue of regioselective access to nitrones by oxidation of nitrogen derivatives.

Tools

History

  • Published In Issue February 01, 2007
  • Received November 24, 2006

Recommend & Share

Related Content

Other ACS content by these authors: