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Letter

Efficient Methodology for Selective Alkylation of Hydrazine Derivatives

Supporting Info

Aleksei Bredihhin,^† Ulrich M. Groth,^‡ and Uno Mäeorg*^†

Institute of Organic and Bioorganic Chemistry, University of Tartu, Jakobi 2, 51014 Tartu, Estonia, and Department of Chemistry, University of Konstanz, Konstanz D-78464, Germany

Org. Lett., 2007, 9 (6), pp 1097–1099

DOI: 10.1021/ol070026w

Publication Date (Web): February 20, 2007

†

University of Tartu.

‡

University of Konstanz.

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, uno@chem.ut.ee

Abstract

Formation and use of a nitrogen dianion for selective hydrazine alkylation is reported. The scope and limitations of a new method were demonstrated. The novel method provides fast and easy access to substituted hydrazines, which are widely used as drugs, pesticides, and precursors for a variety of compounds in organic synthesis.

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