Synthesis of Carbamates and Ureas Using Zr(IV)-Catalyzed Exchange Processes

Chong Han and John A. Porco, Jr*
Department of Chemistry and Center for Chemical Methodology and Library Development, Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215
Org. Lett., 2007, 9 (8), pp 1517–1520
DOI: 10.1021/ol0702728
Publication Date (Web): March 15, 2007
Copyright © 2007 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, porco@bu.edu

Abstract

Abstract Image

Zirconium(IV)-catalyzed exchange processes have been developed to prepare both carbamates and ureas from dialkyl carbonates and carbamates employing 2-hydroxypyridine (HYP) and 4-methyl-2-hydroxyquinoline (MeHYQ) as catalytic additives, respectively. A microwave acceleration effect was observed in Zr(IV)-catalyzed carbamate−urea exchange.

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History

  • Published In Issue April 12, 2007
  • Received February 2, 2007

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