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Letter

Ruthenium-Catalyzed Tandem Cross-Metathesis/Wittig Olefination: Generation of Conjugated Dienoic Esters from Terminal Olefins

Supporting Info

Ryan P. Murelli and Marc L. Snapper*

Merkert Chemistry Center, Boston College, 2609 Beacon Street, Chestnut Hill, Massachusetts 02467-3860

Org. Lett., 2007, 9 (9), pp 1749–1752

DOI: 10.1021/ol070445t

Publication Date (Web): March 31, 2007

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, marc.snapper@bc.edu

Abstract

In the presence of ruthenium-based olefin metathesis catalysts and triphenylphosphine, α,β-unsaturated aldehydes can be olefinated with diazoacetates. This ruthenium-catalyzed transformation has been employed in tandem with olefin cross-metathesis to convert terminal olefins into 1,3-dienoic esters in a single operation.

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Published In Issue April 26, 2007
Received February 21, 2007

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Letter

Ruthenium-Catalyzed Tandem Cross-Metathesis/Wittig Olefination: Generation of Conjugated Dienoic Esters from Terminal Olefins

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Enantioselective Total Synthesis of (−)-Napyradiomycin A1 via Asymmetric Chlorination of an Isolated Olefin

A Short and Efficient Synthesis of (−)-7-Methylomuralide, a Potent Proteasome Inhibitor

Double Bond Isomerization/Enantioselective Aza-Petasis−Ferrier Rearrangement Sequence as an Efficient Entry to Anti- and Enantioenriched β-Amino Aldehydes

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