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Letter

A New Construction of 2-Alkoxypyrans by an Acylation−Reductive Cyclization Sequence

Supporting Info

Lars V. Heumann and Gary E. Keck*

Department of Chemistry, University of Utah, 315 South 1400 East RM 2020, Salt Lake City, Utah 84112-0850

Org. Lett., 2007, 9 (10), pp 1951–1954

DOI: 10.1021/ol070573h

Publication Date (Web): April 12, 2007

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, keck@chemistry.utah.edu

Abstract

A new convergent synthetic approach to a pyran motif common to many naturally occurring structures is described. In this approach, two fragments are joined by esterification, and a subsequent intramolecular reductive cyclization affords the 2-hydroxypyran.

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Published In Issue May 10, 2007
Received March 7, 2007

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Letter

A New Construction of 2-Alkoxypyrans by an Acylation−Reductive Cyclization Sequence

Abstract

Tools

SciFinder Links

History

Recommend & Share

Related Content

Total Synthesis of (−)-Acutumine

Water Overcomes Methyl Group Directing Effects in Epoxide-Opening Cascades

Silylstannylation of Highly Functionalized Acetylenes. Synthesis of Precursors for Annulations via Radical or Heck Reactions

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