Bioactive 2-Oxazolines:  A New Approach via One-Pot, Four-Component Reaction

Lijun Fan, Emil Lobkovsky, and Bruce Ganem*
Department of Chemistry & Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853-1301
Org. Lett., 2007, 9 (10), pp 2015–2017
DOI: 10.1021/ol070694h
Publication Date (Web): April 12, 2007
Copyright © 2007 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, bg18@cornell.edu

Abstract

Abstract Image

Substituted 2-oxazolines of the general structure shown above are found in several families of bioactive natural products and can be prepared in an efficient and general one-pot, four-component condensation.

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History

  • Published In Issue May 10, 2007
  • Received March 21, 2007

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