Letter

Selective Deprotection of Methanesulfonamides to Amines

Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259-B-59 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8501, Japan
Org. Lett., 2010, 12 (6), pp 1228–1230
DOI: 10.1021/ol100086j
Publication Date (Web): February 19, 2010
Copyright © 2010 American Chemical Society

Abstract

Abstract Image

Methanesulfonamides were deprotected to their parent amines via deprotonation and oxygenation with O2 (g), even in the presence of other traditional sulfonamides.

Supporting Information


Physical properties of products. This material is available free of charge via the Internet at http://pubs.acs.org.

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Received 13 January 2010
Published online 19 February 2010
Published in print 19 March 2010
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