Gold-Catalyzed Intramolecular Carbocyclization of Alkynyl Ketones Leading to Highly Substituted Cyclic Enones

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Abstract

The reaction of the internal alkynyl ketones 1 (n = 1) under the combined catalyst, AuCl₃ and AgSbF₆, gave the enones 2 in good to high yields, whereas that of the terminal alkynyl ketones 1 (n = 0) under the combined catalyst, AuCl₃ and AgOTf, afforded the cyclic enones 3.

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This article has been cited by 22 ACS Journal articles (5 most recent appear below).

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  Synthesis of 2-Phenylnaphthalenes through Gold-Catalyzed Dimerization via a Highly Selective Carbon Nucleophile Pathway

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  Tandem Synthesis of 2,3-Dihydro-4-iminoquinolines via Three-Component Alkyne-Imine Metathesis

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