Toward the Synthesis of Spirastrellolide B:  A Synthesis of the C1−C23 Subunit

Katie A. Keaton and Andrew J. Phillips*
Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, Colorado 80309-0215
Org. Lett., 2008, 10 (6), pp 1083–1086
DOI: 10.1021/ol702955m
Publication Date (Web): February 15, 2008
Copyright © 2008 American Chemical Society
*

In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

, andrew.phillips@colorado.edu

Abstract

Abstract Image

A synthesis of the C1−C23 subunit of spirastrellolide B is described. The synthesis features two applications of a Kulinkovich-cyclopropanol ring-opening strategy for the coupling of esters with olefins to produce ketones.

Tools

History

  • Published In Issue March 20, 2008
  • Received December 6, 2007

Recommend & Share

Related Content

Other ACS content by these authors: