Letter
A Formal Synthesis of the Auriside Aglycon
Abstract

A highly convergent formal synthesis of the auriside aglycon was achieved. An indene-based thiazolidinethione chiral auxiliary was used for the construction of both the C1−C9 and C10−C17 fragments via acetate aldol reactions. A Meinwald reaction was utilized to install the stereocenter at C2, and a conjugated addition to an ynone was used to construct the C9−C11 enone.
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History
- Published In Issue June 05, 2008
- Article ASAPMay 08, 2008
- Received: March 13, 2008
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