GFSWeb: A Web Tool for Genome-Based Identification of Proteins from Mass Spectrometric Samples

The interpretation of mass spectrometry data for protein identification has become a vital component of proteomics research. However, since most existing software tools rely on protein databases, their success is limited, especially as the pace of annotation efforts fails to keep pace with sequencing. We present a publicly available, web-based version of a software tool that maps peptide mass fingerprint data directly to their genomic origin, allowing for genome-based, annotation-independent protein identification.

Keywords: mass spectrometry • genome • peptide mass fingerprint • web interface • gene finding • proteomics