Review

Prebiotic Systems Chemistry: New Perspectives for the Origins of Life

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Biophysics Unit (CSIC-UPV/EHU), Leioa, and Department of Logic and Philosophy of Science, University of the Basque Country, Avenida de Tolosa 70, 20080 Donostia−San Sebastián, Spain
Department of Molecular Evolution, Centro de Astrobiología (CSIC−INTA, associated to the NASA Astrobiology Institute), Carretera de Ajalvir, Km 4, 28850 Torrejón de Ardoz, Madrid, Spain
§ Organic Chemistry Department, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain
Chem. Rev., 2014, 114 (1), pp 285–366
DOI: 10.1021/cr2004844
Publication Date (Web): October 31, 2013
Copyright © 2013 American Chemical Society

 Author Contributions

K.R.-M. and C.B. contributed equally to this paper.

Biography

Kepa Ruiz-Mirazo, permanent researcher (former Ramón y Cajal fellow) of the University of the Basque Country (UPV/EHU), has a first degree in physics (solid-state physics), a master’s degree in science education, and a Ph.D. in sciences (complex systems interdisciplinary program). At present, he shares his academic time between the Department of Logic and Philosophy of Science, in Donostia–San Sebastian, and the Biophysics Unit (CSIC-UPV/EHU), in Leioa (Bilbao), developing both experimental and theoretical protocell models, in the wider context of a constant philosophical reflection on the problems of definition, origins, and evolution of life.

Biography

Carlos Briones is a staff scientist of the Spanish National Research Council (CSIC) in the Department of Molecular Evolution at the Centro de Astrobiologı́a (CSIC-INTA, associated to the NASA Astrobiology Institute). He received his Ph.D. in chemistry (biochemistry and molecular biology) in 1997 at the Universidad Autónoma de Madrid. His research interests are mainly focused on the origins and early evolution of life, including experimental and theoretical approaches to the RNA world hypothesis, in vitro evolution of nucleic acids, and genetics of RNA viruses. He is also involved in the development of microarrays and bionanotechnology-inspired biosensors.

Biography

Andrés de la Escosura received his Ph.D. in chemistry in 2005 at the Universidad Autónoma de Madrid, working on molecular and supramolecular materials within the group of Tomás Torres. In 2006, he joined the group of Roeland J. M. Nolte and Jeroen J. L. M. Cornelissen, at the Radboud University Nijmegen, where he held a Marie Curie fellowship and explored the use of protein cages to build biohybrid materials. In 2009, he moved back to the Universidad Autónoma de Madrid, where he has held an Assistant Professor position and, since February 2012, a Ramón y Cajal fellowship. His main research interests are at the interface of chemistry and biology. He is currently working on the construction and study of biohybrid nanomaterials.

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Received 30 December 2011
Published online 31 October 2013
Published in print 8 January 2014