COMBINATORIAL CHEMISTRY
March 8, 1999
Volume 77, Number 10
CENEAR 77 10 p. 43
ISSN 0009-2347

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In dynamic libraries designed by Eliseev and coworkers, the components (A1, A2, A3, A4 . . . An) are in equilibrium with each other. When a component such as A4 binds to an immobilized target compound (T) and is removed from solution, the equilibrium shifts to create more A4. This makes it possible to enrich and identify A4, even if it were initially present only in trace amounts. [Back]


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