Chemical Research in Toxicology (ACS Publications)

Speciation Analysis of Selenium Metabolites in Urine and Breath by HPLC- and GC-Inductively Coupled Plasma-MS after Administration of Selenomethionine and Methylselenocysteine to Rats

Reduced Sensitizing Capacity of Epoxy Resin Systems: A Structure-Activity Relationship Study

Mechanistic Proposal for the Formation of Specific Immunogenic Complexes via a Radical Pathway: A Key Step in Allergic Contact Dermatitis to Olefinic Hydroperoxides

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

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Provides the latest findings on the molecular mechanisms by which toxic agents (chemical and biological) interact with living systems.

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Just Accepted manuscripts are peer-reviewed and accepted for publication. They are posted online prior to technical editing, formatting for publication and author proofing.

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Articles ASAP (As Soon As Publishable)

ASAP articles are edited and published online ahead of print.

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Passive Dosing for Producing Defined and Constant Exposure of Hydrophobic Organic Compounds during in Vitro Toxicity Tests

Kilian E. C. Smith, Gertie J. Oostingh and Philipp Mayer

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 20, 2009 (Article)

DOI: 10.1021/tx900274j

Abstract | Supporting Info

Variation of Keratin 7 Expression and Other Phenotypic Characteristics of Independent Isolates of Cadmium Transformed Human Urothelial Cells (UROtsa)

Seema Somji, Xu Dong Zhou, Aaron Mehus, Mary Ann Sens, Scott H. Garrett, Krista L. Lutz, Jane R. Dunlevy, Yun Zheng and Donald. A. Sens

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 19, 2009 (Article)

DOI: 10.1021/tx900346q

Abstract

Low-Concentration Ozone Reacts with Plasmalogen Glycerophosphoethanolamine Lipids in Lung Surfactant

Kelly M. Wynalda and Robert C. Murphy

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 16, 2009 (Article)

DOI: 10.1021/tx900306p

Abstract | Supporting Info

A Direct Determination of the Dissociation Constant for the Cu(II) Complex of Amyloid β 1−40 Peptide

Małgorzata R

zga, Marcin Kłoniecki, Michał Dadlez and Wojciech Bal

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 13, 2009 (Communication)

DOI: 10.1021/tx900344n

Abstract | Supporting Info

Study of the Metabolism of Estragole in Humans Consuming Fennel Tea

Annette Zeller, Kathie Horst and Michael Rychlik

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 13, 2009 (Article)

DOI: 10.1021/tx900236g

Abstract

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Current Issue

The latest published issue of Chemical Research in Toxicology.

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In this Issue

Chem. Res. Toxicol., 2009, 22 (11), pp 1743–1744

Publication Date (Web): November 16, 2009 (In This Issue)

DOI: 10.1021/tx900349z

Abstract

Spotlight

Chem. Res. Toxicol., 2009, 22 (11), pp 1745–1746

Publication Date (Web): November 16, 2009 (Spotlight)

DOI: 10.1021/tx9003566

Abstract

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

Kent S. Gates

Chem. Res. Toxicol., 2009, 22 (11), pp 1747–1760

Publication Date (Web): September 16, 2009 (Review)

DOI: 10.1021/tx900242k

Abstract

The Chemical Forms of Mercury in Aged and Fresh Dental Amalgam Surfaces

Graham N. George, Satya P. Singh, Jay Hoover and Ingrid J. Pickering

Chem. Res. Toxicol., 2009, 22 (11), pp 1761–1764

Publication Date (Web): October 20, 2009 (Communication)

DOI: 10.1021/tx900309c

Abstract

Mechanism of Formation of (Deoxy)guanosine Adducts Derived from Peroxidase-Catalyzed Oxidation of the Carcinogenic Nonaminoazo Dye 1-Phenylazo-2-hydroxynaphthalene (Sudan I)

Martin Dra

nsk

, Josef Cva

ka, Marcela Semansk

, V

clav Mart

nek, Eva Frei and Marie Stiborov

Chem. Res. Toxicol., 2009, 22 (11), pp 1765–1773

Publication Date (Web): October 9, 2009 (Article)

DOI: 10.1021/tx900201q

Abstract | Supporting Info

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Most Read Articles

Most Read articles are updated on a monthly basis and available as 1 month and 12 month lists. Below is a Top 5 excerpt from the 1 month list.

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Mesoporosity and Functional Group Dependent Endocytosis and Cytotoxicity of Silica Nanomaterials

Zhimin Tao, Bonnie B. Toms, Jerry Goodisman and Tewodros Asefa

Chem. Res. Toxicol., 2009, 22 (11), pp 1869–1880

Publication Date (Web): October 9, 2009 (Article)

DOI: 10.1021/tx900276u

Abstract | Supporting Info

Cytochrome P450 and Chemical Toxicology

F. Peter Guengerich

Chem. Res. Toxicol., 2008, 21 (1), pp 70–83

Publication Date (Web): December 6, 2007 (Perspective)

DOI: 10.1021/tx700079z

Abstract

Metabolism and Toxicity of Drugs. Two Decades of Progress in Industrial Drug Metabolism

Thomas A. Baillie

Chem. Res. Toxicol., 2008, 21 (1), pp 129–137

Publication Date (Web): December 4, 2007 (Perspective)

DOI: 10.1021/tx7002273

Abstract

Glyphosate Formulations Induce Apoptosis and Necrosis in Human Umbilical, Embryonic, and Placental Cells

Nora Benachour and Gilles-Eric S

ralini

Chem. Res. Toxicol., 2009, 22 (1), pp 97–105

Publication Date (Web): December 23, 2008 (Article)

DOI: 10.1021/tx800218n

Abstract

Applying Mechanisms of Chemical Toxicity to Predict Drug Safety

F. Peter Guengerich and James S. MacDonald

Chem. Res. Toxicol., 2007, 20 (3), pp 344–369

Publication Date (Web): February 16, 2007 (Review)

DOI: 10.1021/tx600260a

Abstract

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Most Cited Articles

Most Cited articles are updated on a monthly basis and available as Last 3 Years and All Time lists. Citation data is made available by participants in CrossRef's Cited-by Linking service. Below is an excerpt from the Last 3 Years list (published across all volumes). For a more comprehensive list of citations, users are encouraged to perform a search in SciFinder.

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Role of Quinones in Toxicology

Judy L. Bolton, Michael A. Trush, Trevor M. Penning, Glenn Dryhurst, and Terrence J. Monks

Chem. Res. Toxicol., 2000, 13 (3), pp 135–160

Publication Date (Web): February 23, 2000 (Review)

DOI: 10.1021/tx9902082

Abstract

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Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity

F. Peter Guengerich

Chem. Res. Toxicol., 2001, 14 (6), pp 611–650

Publication Date (Web): May 05, 2001 (Review)

DOI: 10.1021/tx0002583

Abstract

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Oxidative Damage and Tyrosine Nitration from Peroxynitrite

Joseph S. Beckman

Chem. Res. Toxicol., 1996, 9 (5), pp 836–844

Publication Date (Web): July 15, 1996 (Open Forum)

DOI: 10.1021/tx9501445

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Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases

Richard N. Armstrong

Chem. Res. Toxicol., 1997, 10 (1), pp 2–18

Publication Date (Web): January 20, 1997 (Review)

DOI: 10.1021/tx960072x

Abstract

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Biochemistry, Biology, and Carcinogenicity of Tobacco-Specific N-Nitrosamines

Stephen S. Hecht

Chem. Res. Toxicol., 1998, 11 (6), pp 559–603

Publication Date (Web): June 02, 1998 (Review)

DOI: 10.1021/tx980005y

Abstract | Supporting Info

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In This Issue—Highlights from this month's CRT.
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Toxicologists from around the world share their insights on the state of toxicology.

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Reviews and Perspectives on hot topics from our Editorial Advisory Board.

CRT is a major forum for research on the chemical mechanisms of DNA damage. EAB member Kent Gates now provides a seminal review on this important topic in toxicology.
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About the Journal

Just Accepted Manuscripts

Articles ASAP (As Soon As Publishable)

Passive Dosing for Producing Defined and Constant Exposure of Hydrophobic Organic Compounds during in Vitro Toxicity Tests

Variation of Keratin 7 Expression and Other Phenotypic Characteristics of Independent Isolates of Cadmium Transformed Human Urothelial Cells (UROtsa)

Low-Concentration Ozone Reacts with Plasmalogen Glycerophosphoethanolamine Lipids in Lung Surfactant

A Direct Determination of the Dissociation Constant for the Cu(II) Complex of Amyloid β 1−40 Peptide

Study of the Metabolism of Estragole in Humans Consuming Fennel Tea

Current Issue

In this Issue

Spotlight

An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

The Chemical Forms of Mercury in Aged and Fresh Dental Amalgam Surfaces

Mechanism of Formation of (Deoxy)guanosine Adducts Derived from Peroxidase-Catalyzed Oxidation of the Carcinogenic Nonaminoazo Dye 1-Phenylazo-2-hydroxynaphthalene (Sudan I)

Most Read Articles

Mesoporosity and Functional Group Dependent Endocytosis and Cytotoxicity of Silica Nanomaterials

Cytochrome P450 and Chemical Toxicology

Metabolism and Toxicity of Drugs. Two Decades of Progress in Industrial Drug Metabolism

Glyphosate Formulations Induce Apoptosis and Necrosis in Human Umbilical, Embryonic, and Placental Cells

Applying Mechanisms of Chemical Toxicity to Predict Drug Safety

Most Cited Articles

Role of Quinones in Toxicology

Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity

Oxidative Damage and Tyrosine Nitration from Peroxynitrite

Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases

Biochemistry, Biology, and Carcinogenicity of Tobacco-Specific N-Nitrosamines

ACS Divisions

Chemical Tox News

Global Forum

Editorial Perspective

Thematic Compilations

Announcements

Browse By Issue

Stay Current

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