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ASAP articles are edited and published online ahead of print.

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Differential Reactivity of Purified Bioactive Coffee Furans, Cafestol and Kahweol, with Acidic Nitrite: Product Characterization and Factors Controlling Nitrosation Versus Ring-Opening Pathways

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)
Publication Date (Web): November 6, 2009 (Article)
DOI: 10.1021/tx900224x

Disulfides as Cyanide Antidotes: Evidence for a New In Vivo Oxidative Pathway for Cyanide Detoxification

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)
Publication Date (Web): November 5, 2009 (Article)
DOI: 10.1021/tx900258m

Mitochondrial-Driven Ubiquinone Enhances Extracellular Calcium-Dependent Nitric Oxide Production and Reduces Glycochenodeoxycholic Acid-Induced Cell Death in Hepatocytes

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)
Publication Date (Web): November 4, 2009 (Article)
DOI: 10.1021/tx900327t

Stereoselective Metabolism of the Environmental Mammary Carcinogen 6-Nitrochrysene to trans-1,2-Dihydroxy-1,2-dihydro-6-nitrochrysene by Aroclor 1254-Treated Rat Liver Microsomes and Their Comparative Mutation Profiles in a lacI Mammary Epithelial Cell Line

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)
Publication Date (Web): November 3, 2009 (Article)
DOI: 10.1021/tx9002897

Exocyclic Deoxyadenosine Adducts of 1,2,3,4-Diepoxybutane: Synthesis, Structural Elucidation, and Mechanistic Studies

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)
Publication Date (Web): November 2, 2009 (Article)
DOI: 10.1021/tx900312e

Current Issue

The latest published issue of Chemical Research in Toxicology.

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In this Issue

Chem. Res. Toxicol., 2009, 22 (10), pp 1649–1650
Publication Date (Web): October 19, 2009 (In This Issue)
DOI: 10.1021/tx900308x
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Spotlight

Chem. Res. Toxicol., 2009, 22 (10), pp 1651–1652
Publication Date (Web): October 19, 2009 (Spotlight)
DOI: 10.1021/tx9002885

A Holistic Strategy for Characterizing the Safety of Metabolites through Drug Discovery and Development

Chem. Res. Toxicol., 2009, 22 (10), pp 1653–1662
Publication Date (Web): August 31, 2009 (Review)
DOI: 10.1021/tx900213j

Reductive Activation of Mitomycin C by Thiols: Kinetics, Mechanism, and Biological Implications

Chem. Res. Toxicol., 2009, 22 (10), pp 1663–1668
Publication Date (Web): September 30, 2009 (Communication)
DOI: 10.1021/tx9002758

Chemical Synthesis of Two Series of Nerve Agent Model Compounds and Their Stereoselective Interaction with Human Acetylcholinesterase and Human Butyrylcholinesterase

Chem. Res. Toxicol., 2009, 22 (10), pp 1669–1679
Publication Date (Web): August 31, 2009 (Article)
DOI: 10.1021/tx900096j

Most Read Articles

Most Read articles are updated on a monthly basis and available as 1 month and 12 month lists. Below is a Top 5 excerpt from the 1 month list.

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Mesoporosity and Functional Group Dependent Endocytosis and Cytotoxicity of Silica Nanomaterials

Chem. Res. Toxicol., Articles ASAP (As Soon As Publishable)
Publication Date (Web): October 9, 2009 (Article)
DOI: 10.1021/tx900276u

Cytochrome P450 and Chemical Toxicology

Chem. Res. Toxicol., 2008, 21 (1), pp 70–83
Publication Date (Web): December 6, 2007 (Perspective)
DOI: 10.1021/tx700079z

Metabolism and Toxicity of Drugs. Two Decades of Progress in Industrial Drug Metabolism

Chem. Res. Toxicol., 2008, 21 (1), pp 129–137
Publication Date (Web): December 4, 2007 (Perspective)
DOI: 10.1021/tx7002273
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Glyphosate Formulations Induce Apoptosis and Necrosis in Human Umbilical, Embryonic, and Placental Cells

Chem. Res. Toxicol., 2009, 22 (1), pp 97–105
Publication Date (Web): December 23, 2008 (Article)
DOI: 10.1021/tx800218n
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Applying Mechanisms of Chemical Toxicity to Predict Drug Safety

Chem. Res. Toxicol., 2007, 20 (3), pp 344–369
Publication Date (Web): February 16, 2007 (Review)
DOI: 10.1021/tx600260a

Most Cited Articles

Most Cited articles are updated on a monthly basis and available as Last 3 Years and All Time lists. Citation data is made available by participants in CrossRef's Cited-by Linking service. Below is an excerpt from the Last 3 Years list (published across all volumes). For a more comprehensive list of citations, users are encouraged to perform a search in SciFinder.

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Role of Quinones in Toxicology

Chem. Res. Toxicol., 2000, 13 (3), pp 135–160
Publication Date (Web): February 23, 2000 (Review)
DOI: 10.1021/tx9902082

Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity

Chem. Res. Toxicol., 2001, 14 (6), pp 611–650
Publication Date (Web): May 05, 2001 (Review)
DOI: 10.1021/tx0002583

Oxidative Damage and Tyrosine Nitration from Peroxynitrite

Chem. Res. Toxicol., 1996, 9 (5), pp 836–844
Publication Date (Web): July 15, 1996 (Open Forum)
DOI: 10.1021/tx9501445

Structure, Catalytic Mechanism, and Evolution of the Glutathione Transferases

Chem. Res. Toxicol., 1997, 10 (1), pp 2–18
Publication Date (Web): January 20, 1997 (Review)
DOI: 10.1021/tx960072x

Biochemistry, Biology, and Carcinogenicity of Tobacco-Specific N-Nitrosamines

Chem. Res. Toxicol., 1998, 11 (6), pp 559–603
Publication Date (Web): June 02, 1998 (Review)
DOI: 10.1021/tx980005y

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Chemical Tox News

  • In This Issue—Highlights from this month's CRT.
  • Spotlight—Chemical toxicology highlights from the field.
  • More MIST — CRT's February special issue on drug Metabolites In Safety Testing continues to generate interest. See the new perspective this month by Walker et al.

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Toxicologists from around the world share their insights on the state of toxicology.

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