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Combinatorial Materials Research Applied to the Development of New Surface Coatings XIII: An Investigation of Polysiloxane Antimicrobial Coatings Containing Tethered Quaternary Ammonium Salt Groups

Efficient Construction of Diketopiperazine Macroarrays Through a Cyclative-Cleavage Strategy and Their Evaluation as Luminescence Inhibitors in the Bacterial Symbiont Vibrio fischeri

Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ Screening

High Resolution Mass Spectrometry for Rapid Characterization of Combinatorial Peptide Libraries

Solid-phase Synthesis of Tertiary N-Methyl Amines Including Tropanes

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The Journal of Combinatorial Chemistry is an interdisciplinary journal that opens up channels of information for synthetic organic chemists, medicinal and analytical chemists, pharmaceutical scientists, biotechnologists, computational chemists, material scientists, and agrochemists.

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Just Accepted manuscripts are peer-reviewed and accepted for publication. They are posted online prior to technical editing, formatting for publication and author proofing.

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Articles ASAP (As Soon As Publishable)

ASAP articles are edited and published online ahead of print.

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Combinatorial Synthesis of Substituted Thieno[3,2-b]pyridines and Other Annulated Heterocycles via New S_N2 → Thorpe−Ziegler → Thorpe−Guareschi Domino Reactions

Anatoliy M. Shestopalov, Lyudmila A. Rodinovskaya and Alexander A. Shestopalov

J. Comb. Chem., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 20, 2009 (Report)

DOI: 10.1021/cc9001372

Abstract | Supporting Info

Microwave Assisted Efficient Synthesis of Imidazole-Based Privileged Structures

Marco Fantini, Valentina Zuliani, Mario A. Spotti and Mirko Rivara

J. Comb. Chem., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 18, 2009 (Article)

Abstract

Facile Route to 1,3-Diazaheterocycle-Fused [1,2b]Isoquinolin-1(2H)-one Derivatives via Substitution-Cyclization Reactions

Shengjiao Yan, Chao Huang, Cunxiang Su, Yongfen Ni and Jun Lin

J. Comb. Chem., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 13, 2009 (Article)

DOI: 10.1021/cc900121c

Abstract | Supporting Info

Simple and Convenient Approach to the Kr€ohnke Pyridine Type Synthesis of Functionalized Indol-3-yl Pyridine Derivatives Using 3-Cyanoacetyl Indole

Prakasam Thirumurugan, A. Nandakumar, D. Muralidharan and Paramasivan T. Perumal

J. Comb. Chem., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 11, 2009 (Article)

DOI: 10.1021/cc9001394

Abstract | Supporting Info

Novel One-Pot Three Component Reaction for the Synthesis of [2-(Alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone

Ebrahim Kianmehr, Mohammad Ghanbari, Mehri Nadiri Niri and Reza Faramarzi

J. Comb. Chem., Articles ASAP (As Soon As Publishable)

Publication Date (Web): November 11, 2009 (Article)

DOI: 10.1021/cc900103r

Abstract | Supporting Info

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Current Issue

The latest published issue of Journal of Combinatorial Chemistry.

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Preparation and Optimization of Iridium Complexes with Quinazolinone Ligands on Solid Supports

Nai-Mu Hsu, Chung-Yen Li, Chun-Mei Yang, Tzu-Sheng Lin, Bi-Han Hu, Yogesh S. Tingare, Wei-Chun Chang, Gaurav Kumar Srivastava and Wen-Ren Li

J. Comb. Chem., 2009, 11 (6), pp 943–946

Publication Date (Web): October 7, 2009 (Report)

DOI: 10.1021/cc900104j

Abstract | Supporting Info

Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ Screening

Romain Duval, St

phanie Kolb, Emmanuelle Braud, David Genest and Christiane Garbay

J. Comb. Chem., 2009, 11 (6), pp 947–950

Publication Date (Web): October 16, 2009 (Report)

DOI: 10.1021/cc900140f

Abstract | Supporting Info

Solid-Phase Synthesis of 3-Hydroxy-6-Nitroquinolin-4(1H)-ones with Two Diversity Positions

a K

upkov

, Miroslav Soural, Jan Hlav

and Pavel Hradil

J. Comb. Chem., 2009, 11 (6), pp 951–955

Publication Date (Web): September 24, 2009 (Article)

DOI: 10.1021/cc900068w

Abstract | Supporting Info

Novel One-Pot Three- and Pseudo-Five-Component Reactions: Synthesis of Functionalized Benzo[g]- and Dihydropyrano[2,3-g]chromene Derivatives

Ahmad Shaabani, Rahim Ghadari, Sabrieh Ghasemi, Milad Pedarpour, Ali Hossein Rezayan, Afshin Sarvary and Seik Weng Ng

J. Comb. Chem., 2009, 11 (6), pp 956–959

Publication Date (Web): September 22, 2009 (Article)

DOI: 10.1021/cc900101w

Abstract | Supporting Info

Solid-Phase Organic Synthesis of Difluoroalkyl Entities using a Novel Fluorinating Cleavage Strategy: Part 1. Linker Development: Scope and Limitations

Matthias S. Wiehn, Stephen D. Lindell and Stefan Br

J. Comb. Chem., 2009, 11 (6), pp 960–981

Publication Date (Web): September 1, 2009 (Article)

DOI: 10.1021/cc900090p

Abstract | Supporting Info

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Most Read articles are updated on a monthly basis and available as 1 month and 12 month lists. Below is a Top 5 excerpt from the 1 month list.

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Preparation of a Library of EDTA Amide x-Aminenaphthalene-y-sulfonic Acid Derivatives on Solid Phase and Their Fluorescence Behavior toward Transition Metals

Hisila Santacruz Ortega, Georgina Pina-Luis, Sara Karime L

pez and Ignacio A. Rivero

J. Comb. Chem., 2009, 11 (6), pp 1030–1037

Publication Date (Web): October 12, 2009 (Article)

DOI: 10.1021/cc900075r

Abstract | Supporting Info

Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2008

Roland E. Dolle, Bertrand Le Bourdonnec, Allan J. Goodman, Guillermo A. Morales, Craig J. Thomas and Wei Zhang

J. Comb. Chem., 2009, 11 (5), pp 739–790

Publication Date (Web): August 28, 2009 (Review)

Abstract

Microwave-Assisted Fluorous Synthesis of a 1,4-Benzodiazepine-2,5-dione Library

Aifeng Liu, Hongyu Zhou, Gaoxing Su, Wei Zhang and Bing Yan

J. Comb. Chem., 2009, 11 (6), pp 1083–1093

Publication Date (Web): October 6, 2009 (Article)

DOI: 10.1021/cc900109e

Abstract | Supporting Info

Solid-Phase Synthesis of Biologically Active Benzoannelated Nitrogen Heterocycles: An Update

Carmen Gil and Stefan Br

J. Comb. Chem., 2009, 11 (2), pp 175–197

Publication Date (Web): November 14, 2008 (Review)

DOI: 10.1021/cc800102t

Abstract

Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ Screening

Romain Duval, St

phanie Kolb, Emmanuelle Braud, David Genest and Christiane Garbay

J. Comb. Chem., 2009, 11 (6), pp 947–950

Publication Date (Web): October 16, 2009 (Report)

DOI: 10.1021/cc900140f

Abstract | Supporting Info

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Most Cited Articles

Most Cited articles are updated on a monthly basis and available as Last 3 Years and All Time lists. Citation data is made available by participants in CrossRef's Cited-by Linking service. Below is an excerpt from the Last 3 Years list (published across all volumes). For a more comprehensive list of citations, users are encouraged to perform a search in SciFinder.

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Comprehensive Survey of Combinatorial Library Synthesis: 1998

Roland E. Dolle and Kingsley H. Nelson, Jr.

J. Comb. Chem., 1999, 1 (4), pp 235–282

Publication Date (Web): July 13, 1999 (Review)

DOI: 10.1021/cc9900192

Abstract

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Increasing Rates of Reaction: Microwave-Assisted Organic Synthesis for Combinatorial Chemistry

Amy Lew, Peter O. Krutzik, Matthew E. Hart, and A. Richard Chamberlin

J. Comb. Chem., 2002, 4 (2), pp 95–105

Publication Date (Web): December 13, 2001 (Review)

DOI: 10.1021/cc010048o

Abstract

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A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases

Arup K. Ghose, Vellarkad N. Viswanadhan, and John J. Wendoloski

J. Comb. Chem., 1999, 1 (1), pp 55–68

Publication Date (Web): December 18, 1998 (Article)

DOI: 10.1021/cc9800071

Abstract

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Comprehensive Survey of Combinatorial Library Synthesis: 2000

Roland E. Dolle

J. Comb. Chem., 2001, 3 (6), pp 477–517

Publication Date (Web): October 06, 2001 (Review)

DOI: 10.1021/cc010049g

Abstract

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Solution- and Solid-Phase Strategies for the Design, Synthesis, and Screening of Libraries Based on Natural Product Templates: A Comprehensive Survey

Dennis G. Hall, Sukhdev Manku, and Fan Wang

J. Comb. Chem., 2001, 3 (2), pp 125–150

Publication Date (Web): February 08, 2001 (Review)

DOI: 10.1021/cc0001001

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Just Accepted Manuscripts

Articles ASAP (As Soon As Publishable)

Combinatorial Synthesis of Substituted Thieno[3,2-b]pyridines and Other Annulated Heterocycles via New S_N2 → Thorpe−Ziegler → Thorpe−Guareschi Domino Reactions

Microwave Assisted Efficient Synthesis of Imidazole-Based Privileged Structures

Facile Route to 1,3-Diazaheterocycle-Fused [1,2b]Isoquinolin-1(2H)-one Derivatives via Substitution-Cyclization Reactions

Simple and Convenient Approach to the Kr€ohnke Pyridine Type Synthesis of Functionalized Indol-3-yl Pyridine Derivatives Using 3-Cyanoacetyl Indole

Novel One-Pot Three Component Reaction for the Synthesis of [2-(Alkylsulfanyl)imidazo[1,2-a]pyridin-3-yl](aryl)methanone

Current Issue

Preparation and Optimization of Iridium Complexes with Quinazolinone Ligands on Solid Supports

Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ Screening

Solid-Phase Synthesis of 3-Hydroxy-6-Nitroquinolin-4(1H)-ones with Two Diversity Positions

Novel One-Pot Three- and Pseudo-Five-Component Reactions: Synthesis of Functionalized Benzo[g]- and Dihydropyrano[2,3-g]chromene Derivatives

Solid-Phase Organic Synthesis of Difluoroalkyl Entities using a Novel Fluorinating Cleavage Strategy: Part 1. Linker Development: Scope and Limitations

Most Read Articles

Preparation of a Library of EDTA Amide x-Aminenaphthalene-y-sulfonic Acid Derivatives on Solid Phase and Their Fluorescence Behavior toward Transition Metals

Comprehensive Survey of Chemical Libraries for Drug Discovery and Chemical Biology: 2008

Microwave-Assisted Fluorous Synthesis of a 1,4-Benzodiazepine-2,5-dione Library

Solid-Phase Synthesis of Biologically Active Benzoannelated Nitrogen Heterocycles: An Update

Rapid Discovery of Triazolobenzylidene-Thiazolopyrimidines (TBTP) as CDC25 Phosphatase Inhibitors by Parallel Click Chemistry and in Situ Screening

Most Cited Articles

Comprehensive Survey of Combinatorial Library Synthesis: 1998

Increasing Rates of Reaction: Microwave-Assisted Organic Synthesis for Combinatorial Chemistry

A Knowledge-Based Approach in Designing Combinatorial or Medicinal Chemistry Libraries for Drug Discovery. 1. A Qualitative and Quantitative Characterization of Known Drug Databases

Comprehensive Survey of Combinatorial Library Synthesis: 2000

Solution- and Solid-Phase Strategies for the Design, Synthesis, and Screening of Libraries Based on Natural Product Templates: A Comprehensive Survey

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Announcements

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