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Molecular Pharmaceutics concentrates on the integration of applications of the chemical and biological sciences to advance the development of new drugs and delivery systems.

Editors: Gordon L. Amidon & Associate Editors | Editorial Advisory Board
Volume: 5, 6 issues
ISI Impact Factor: 11.030
Total Citations: 3,216

Articles ASAP (As Soon As Publishable)

The Most Recently Published Research

The following list of Articles ASAP is limited to the latest 20 articles. Visit the All Articles ASAP page for the complete listing.

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Web Release Date: July 24, 2008
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Effects of Monoglycerides on P-Glycoprotein: Modulation of the Activity and Expression in Caco-2 Cell Monolayers
Cheri A. Barta, Kristina Sachs-Barrable, Florina Feng, and Kishor M. Wasan
Web Release Date: 24-Jul-2008; (Article) DOI:
10.1021/mp800050q
Abstract   Full:  HTML /  PDF (256K) 
Web Release Date: July 23, 2008
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Surfactant−Polymer Nanoparticles Enhance the Effectiveness of Anticancer Photodynamic Therapy
Ayman Khdair, Brigitte Gerard, Hitesh Handa, Guangzhao Mao, Malathy P. V. Shekhar, and Jayanth Panyam
Web Release Date: 23-Jul-2008; (Article) DOI:
10.1021/mp800026t
Abstract   Full:  HTML /  PDF (1453K) 
Web Release Date: July 16, 2008
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Characterization of the In Situ Structural and Interfacial Properties of the Cationic Hydrophobic Heteropolypeptide, KL4, in Lung Surfactant Bilayer and Monolayer Models at the Air−Water Interface: Implications for Pulmonary Surfactant Delivery
Heidi M. Mansour, Srinivasan Damodaran, and George Zografi
Web Release Date: 16-Jul-2008; (Article) DOI:
10.1021/mp700123p
Abstract   Full:  HTML /  PDF (1053K) 
Web Release Date: July 12, 2008
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In Silico Drug Profiling of the Human Kinome Based on a Molecular Marker for Cross Reactivity
Xi Zhang and Ariel Fernández
Web Release Date: 12-Jul-2008; (Article) DOI:
10.1021/mp800010p
Abstract   Full:  HTML /  PDF (2375K) 
Web Release Date: July 11, 2008
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Biodistribution and Pharmacokinetic Analysis of Paclitaxel and Ceramide Administered in Multifunctional Polymer-Blend Nanoparticles in Drug Resistant Breast Cancer Model
Lilian E. van Vlerken, Zhenfeng Duan, Steven R. Little, Michael V. Seiden, and Mansoor M. Amiji
Web Release Date: 11-Jul-2008; (Article) DOI:
10.1021/mp800030k
Submitted for publication in the special issue: Biodistribution of Nanomedicines
Abstract   Full:  HTML /  PDF (1305K) 
Web Release Date: July 10, 2008
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Induced Disorder in Protein−Ligand Complexes as a Drug-Design Strategy
Alejandro Crespo and Ariel Fernández
Web Release Date: 10-Jul-2008; (Addition and Correction) DOI:
10.1021/mp8000777
Full:  HTML /  PDF (23K) 
Web Release Date: July 9, 2008
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Combating the Threat of Anthrax: A Quantitative Structure−Activity Relationship Approach
Rajeshwar P. Verma and Corwin Hansch
Web Release Date: 09-Jul-2008; (Article) DOI:
10.1021/mp8000149
Abstract   Full:  HTML /  PDF (289K) 
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Pharmacokinetics and Biodistribution of Nanoparticles
Shyh-Dar Li and Leaf Huang
Web Release Date: 09-Jul-2008; (Review) DOI:
10.1021/mp800049w
Submitted for publication in the special issue: Biodistribution of Nanomedicines
Abstract   Full:  HTML /  PDF (323K) 
Web Release Date: June 19, 2008
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Investigation of the Redox Behavior of Ferroquine, a New Antimalarial
Natascha Chavain, Hervé Vezin, Daniel Dive, Nadia Touati, Jean-François Paul, Eric Buisine, and Christophe Biot
Web Release Date: 19-Jun-2008; (Article) DOI:
10.1021/mp800007x
Abstract   Full:  HTML /  PDF (313K)  Supporting Info 
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Cationic Phospholipids Forming Cubic Phases: Lipoplex Structure and Transfection Efficiency
Rumiana Koynova, Li Wang, and Robert C. MacDonald
Web Release Date: 19-Jun-2008; (Article) DOI:
10.1021/mp800011e
Abstract   Full:  HTML /  PDF (887K) 
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Comparative Proteomic Analysis of Extracellular Proteins Reveals Secretion of T-Kininogen from Vascular Smooth Muscle Cells in Response to Incubation with S-Enantiomer of Propranolol
Jianjun Sui, Jianhua Zhang, Chi Bun Ching, and Wei Ning Chen
Web Release Date: 19-Jun-2008; (Brief Article) DOI:
10.1021/mp800012x
Abstract   Full:  HTML /  PDF (522K) 
Web Release Date: June 17, 2008
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Assessment of Golgi Apparatus versus Plasma Membrane-Localized Multi-Drug Resistance-Associated Protein 1
Allyn M. Kaufmann, Alana J. Toro-Ramos, and Jeffrey P. Krise
Web Release Date: 17-Jun-2008; (Article) DOI:
10.1021/mp8000205
Abstract   Full:  HTML /  PDF (1167K) 
Web Release Date: June 12, 2008
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PEG-b-PPS Diblock Copolymer Aggregates for Hydrophobic Drug Solubilization and Release: Cyclosporin A as an Example
Diana Velluto, Davide Demurtas, and Jeffrey A. Hubbell
Web Release Date: 12-Jun-2008; (Article) DOI:
10.1021/mp7001297
Abstract   Full:  HTML /  PDF (774K) 
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Applications of Physiologically Based Absorption Models in Drug Discovery and Development
Neil Parrott and Thierry Lave
Web Release Date: 12-Jun-2008; (Article) DOI:
10.1021/mp8000155
Abstract   Full:  HTML /  PDF (1993K) 
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Anticancer Therapeutics: Targeting Macromolecules and Nanocarriers to Hyaluronan or CD44, a Hyaluronan Receptor
Virginia M. Platt and Francis C. Szoka Jr.
Web Release Date: 12-Jun-2008; (Review) DOI:
10.1021/mp800024g
Submitted for publication in the special issue: Biodistribution of Nanomedicines
Abstract   Full:  HTML /  PDF (1380K) 
Web Release Date: June 7, 2008
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Synthesis, Characterization, and Biological Evaluation of Integrin αvβ3-Targeted PAMAM Dendrimers
C. Andrew Boswell, Peter K. Eck, Celeste A. S. Regino, Marcelino Bernardo, Karen J. Wong, Diane E. Milenic, Peter L. Choyke, and Martin W. Brechbiel
Web Release Date: 07-Jun-2008; (Article) DOI:
10.1021/mp800022a
Submitted for publication in the special issue: Biodistribution of Nanomedicines
Abstract   Full:  HTML /  PDF (1295K)  Supporting Info 
Web Release Date: June 5, 2008
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NMR Spectroscopic Evaluation of the Internal Environment of PLGA Microspheres
Kirby C. Wong-Moon, Xin Sun, Xichdao C. Nguyen, Bin P. Quan, Kai Shen, and Paul A. Burke
Web Release Date: 05-Jun-2008; (Article) DOI:
10.1021/mp7001522
Abstract   Full:  HTML /  PDF (323K)  Supporting Info 
Web Release Date: May 30, 2008
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Effects of Triton X-100 Nanoaggregates on Dimerization and Antioxidant Activity of Morin
Weiya Liu and Rong Guo
Web Release Date: 30-May-2008; (Article) DOI:
10.1021/mp7001413
Abstract   Full:  HTML /  PDF (757K)  Supporting Info 
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Preclinical Studies To Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution
Marina A. Dobrovolskaia, Parag Aggarwal, Jennifer B. Hall, and Scott E. McNeil
Web Release Date: 30-May-2008; (Review) DOI:
10.1021/mp800032f
Submitted for publication in the special issue: Biodistribution of Nanomedicines
Abstract   Full:  HTML /  PDF (1254K) 
Web Release Date: May 29, 2008
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New Cationic Liposomes as Vehicles of m-Tetrahydroxyphenylchlorin in Photodynamic Therapy of Infectious Diseases
Cecilia Bombelli, Federico Bordi, Stefania Ferro, Luisa Giansanti, Giulio Jori, Giovanna Mancini, Claudia Mazzuca, Donato Monti, Fernanda Ricchelli, Simona Sennato, and Mariano Venanzi
Web Release Date: 29-May-2008; (Article) DOI:
10.1021/mp800037d
Abstract   Full:  HTML /  PDF (121K)  Supporting Info 
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