National Chemistry Week 2006
 |
In celebration of National Chemistry Week, ACS Publications has listed over 100 current “Hot Papers” as recognized by Thomson ISI®’s Essential Science Indicators. Hot Papers are articles published within the last 2 years receiving the most citations over the most recent 2-month period. For the current two month period, the ISI® recognizes 244 total Hot Papers in chemistry alone, with ACS Publications accounting for 41 of the top 100, or more than 40% of the ‘hottest’ papers in chemistry!
Listed below are the Hot Papers from Journal of Medicinal Chemistry for September-October 2006:
- Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
Bruce L. Grasberger, Tianbao Lu, Carsten Schubert, Daniel J. Parks, Theodore E. Carver, Holly K. Koblish, Maxwell D. Cummings, Louis V. LaFrance, Karen L. Milkiewicz, Raul R. Calvo, Diane Maguire, Jennifer Lattanze, Carol F. Franks, Shuyuan Zhao, Kannan Ramachandren, Gwendolyn R. Bylebyl, Marie Zhang, Carl L. Manthey, Eugene C. Petrella, Michael W. Pantoliano, Ingrid C. Deckman, John C. Spurlino, Anna C. Maroney, Bruce E. Tomczuk, Christopher J. Molloy, and Roger F. Bone
J. Med. Chem.; 2005; 48(4) pp 909 - 912; (Letter); DOI: 10.1021/jm049137g
Access: Abstract / HTML / PDF (188K) / Supporting Info - Structure-Based Design, Synthesis, and Memapsin 2 (BACE) Inhibitory Activity of Carbocyclic and Heterocyclic Peptidomimetics
Stephen Hanessian, Hongying Yun, Yihua Hou, Gaoqiang Yang, Malken Bayrakdarian, Eric Therrien, Nicolas Moitessier, Silvio Roggo, Siem Veenstra, Marina Tintelnot-Blomley, Jean-Michel Rondeau, Christian Ostermeier, André Strauss, Paul Ramage, Paolo Paganetti, Ulf Neumann, and Claudia Betschart
J. Med. Chem.; 2005; 48(16) pp 5175 - 5190; (Article); DOI: 10.1021/jm050142+
Access: Abstract / HTML / PDF (433K) / Supporting Info
