FEATURES

779 A
On the cover. Automating Analytical Separations in Radiochemistry.
Sequential injection techniques offer a versatile fluid-handling approach that can be automated for chemical separations--including the delivery of material to pack the column. Jay W. Grate and Oleg B. Egorov of Pacific Northwest National Laboratory discuss how this approach, integrated with on-line radiometric or mass spectrometric detection, provides an automated analysis technique for radioisotopes in nuclear waste.

790 A
Cooperative Group Learning in Undergraduate Analytical Chemistry.
A recent report from two NSF-funded workshops on undergraduate analytical education recommends introducing problem-based learning into the curriculum. Many professors, however, are unfamiliar with this approach. Thomas J. Wenzel of Bates College provides some pointers based on his eight years of experience with the problem-based learning approach.


NEWS

767 A
Analytical Currents
Thin films in action.  H/D exchange.  Ca2+/peptide binding in the gas-phase.  Blame it on the gold.  Human spliceosome characterized with MS.  Finding molecules in a bind.  Bright lights for biomolecules.  Ultrafine multicomponent aerosol particles.  Fritless electrospray.  LIBS and Raman, together at last.

771 A
Science
A sensor to stick with. Purnendu "Sandy" Dasgupta and his colleagues at Texas Tech University, working with Su-Yi Liu of World Precision Instruments, use a polymer with the lowest refractive index of any known polymer to create a new class of gas sensors for environmental and occupational health applications.  Sensitive liquid crystals. Compact, inexpensive, and portable are key characteristics of the liquid crystal sensor system being developed by British scientists Paul Nicholas and Jim Hay of Birmingham University and David Lacey of Hull University.  Microscale separations go online with MS. Terry D. Lee and his co-workers at The City of Hope combine two ideas to produce a microscale electrospray interface that includes a polymeric support inside the needle for separations.  DNA/cation binding at micropipets.After solving some technical problems, Michael V. Mirkin of Queens College CUNY and B. R. Horrocks of the University of Newcastle-upon-Tyne (United Kingdom) use ion-transfer voltammetry at micropipet electrodes to measure cation binding to DNA.  Microfabrication without a cleanroom. George M. Whitesides and his co-workers at Harvard University create microscale patterns on surfaces by using elastomeric masters and a new approach for microcontact printing.  Switching off to drugs. An ion-switch biosensor, developed by Bruce Cornell's group at the Cooperative Research Centre for Molecular Engineering and Technology (Australia), is catching the eye of pharmaceutical companies.

774 A
Business
Park Scientific and TopoMetrix become ThermoMicroscopes.

775 A
News from Micro-TAS
Micro-TAS 1998.  Under pressure.  Tiny torches.

776 A
News from FACSS
Them bones, them bones.

777 A
News from the Frederick Conference on CE
96-capillary array.  Diagnosing heart attacks.  2-D chip-based system for peptide analysis.

777 A
People
Frederick Conference Award on CE.  Nominations for Technology Medal and Inventors Hall of Fame.  1999 ACS awards.  Rechnitz receives Regents' Medal.


DEPARTMENTS

755 A
Editorial
Analytical chemistry at NIST. The Editor salutes one of the outstanding analytical chemistry establishments in the United States.

759 A
In AC Research

797 A
Focus
Toxicants in the environment: Are we being exposed?
Whether it is a natural disaster or a dangerous chemical spill, the world turns to the National Center for Environmental Health--one of the many parts of the Centers for Disease Control and Prevention--for quick answers to difficult and life-threatening problems.

801 A
Product Review
Is there new life ahead for hyphenated IR? Despite a flat market, GC/FT-IR systems continue to evolve.

806 A
Meetings
Pittcon '99. Preliminary program for the 50th Pittsburgh Conference and Exposition on Analytical Chemistry and Applied Spectroscopy.  WCBP '99. Program for the Well-Characterized Biotechnology Pharmaceuticals meeting in Washington, D.C.  Conferences.  Short course.

812 A
Books
IR for newcomers. Modern Techniques in Applied Molecular Spectroscopy is reviewed by Bruce Chase of DuPont  Complete coverage of chemometrics. Handbook of Chemometrics and Qualimetrics: Part A is reviewed by Steven D. Brown of the University of Delaware.

814 A
New Products
A sulfur-specific HPLC detector, a CCD system, and a tunable dye laser are featured.  Instrumentation.  Literature.  Columns.  Catalogs.

816 A
Five-Year Index of A-Page Articles

830 A
Information Express

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