148 A
SELDI-TOF
MS for Diagnostic Proteomics. (798 KB PDF)
Finding biomarkers of early stage cancer would help save lives, but commonly used
gel electrophoresis techniques are laborious and far from flawless. Haleem J.
Issaq, Thomas P. Conrads, DaRue A. Prieto, Radhakrishna Tirumalai, and Timothy
D. Veenstra from the National Cancer Institute describe the benefits of surface-enhanced
laser desorption/ionization, a technique that has attributes in common with MALDI.
156 A
Sulfonic
Acid Derivatives for Peptide Sequencing by MALDI MS. (548
KB PDF)
Chromatography is the traditional method used to determine chirality, but MS techniques
can be adapted to be quantitative. W. Andy Tao and R. Graham Cooks at Purdue University
outline an MS method to test for chirality on the basis of competitive dissociation
of metal ion-bound cluster ions.
166 A
Scientists
Create Bonds with Artists. (458 KB PDF)
Researchers once recorded their observations in painstakingly detailed artwork,
but the connection between science and art languished when modern imaging techniques
arrived. Michael Felton and Rachel Petkewich find scientists and artists who initiate
projects that better communicate science to the public. |
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