TABLE OF CONTENTS
February 15, 1999
Volume 77, Number 7
CENEAR 77 7 p. 3
ISSN 0009-2347

Quote of the Week

"With results like these, who wants to be in a hurry?" Chairman and CEO of a chemical company commenting on the industry's slowness in releasing 1998 financial results. page 29%


NEWS OF THE WEEK

CHEMICAL RISK:   9
Houston-area companies present risk management plans to the public.

MITSUBISHI SLIMS DOWN:   9
Japanese chemical firm says it will close plants, reduce staff, and cut pay.

HOLEY POLYMERS:   10
Spheres are template for organic materials with ordered array of nanometer-sized holes.

SMITHKLINE REFOCUSES:   10
Company takes loss on noncore businesses; concentrates on pharmaceuticals.

DOUBT CAST ON CW CLAIM:   11
Carefully controlled study finds no trace of chemical weapon precursor at bombed Sudanese drug plant.

SUPERCRITICAL CO2:   12
Benign solvent has unexpected, dramatic effect in stereocontrolled synthesis.

BUSINESS

BUSINESS CONCENTRATES:  15

LICENSING FOR PROFIT:   19
Large drug companies are deriving increasing share of revenues from licensed products.

CHEMICAL EARNINGS:   29
Low prices and slow exports drive down earnings for fourth-quarter and full-year 1998.

PHARMACEUTICAL EARNINGS:   33
Drug company sales and earnings are up for fourth quarter and year.

GOVERNMENT

GOVERNMENT CONCENTRATES:  36

COVER STORY

FEDERAL R&D BUDGET:   37
Total funding falls 1%, but NSF and NIH will see modest increases.

GOVERNMENT INSIGHTS:   49
Citizen activist organizations and industry clash on information for consumers in pesticide brochure.

SCIENCE/TECHNOLOGY

SCIENCE/TECHNOLOGY CONCENTRATES:  51

LAB DESIGN:   53
Nurturing research with buildings that stimulate creativity and foster interaction among scientists.

PROTEIN NMR:   65
Segmental isotope-labeling technique opens large proteins to the power of NMR structural determinations.

POLYANILINE SYNTHESIS:  68
Horseradish peroxidase provides clean route to conducting polymer.

WHAT'S THAT STUFF?:   70
The stretchy world of spandex.

THE DEPARTMENTS

EDITOR'S PAGE

LETTERS

72 SOFTWARE/ONLINE BRIEFS

94 PEOPLE

96 NEWSCRIPTS


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Copyright © 1999 American Chemical Society