CISPLATIN:   9
Crystal structure offers clues to molecular action of anticancer drug.

CHEMICAL RISK:   10
Access to risk management plans is still a hot issue.

UNUSUAL REDUCTION:   10
Bulky ligands transform lanthanide into effective reducing agent.

U.K. BIOTECH MERGER:   11
Chiroscience and Celltech seek critical mass and sustainable profits.

BROMINE PRICE FIXING?:   11
Great Lakes Chemical sought government scrutiny.

Pd TO THE RESCUE:   12
Palladium catalysts facilitate synthesis of aminoaryl nucleosides.

BUSINESS CONCENTRATES:  13

CORPORATE CUTS:   15
Layoffs may boost shareholder equity, but they wreak havoc with employees' lives.

WORLD CHEMICAL FORUM:   20
Business leaders share their ideas on challenges in the new millennium.

GOVERNMENT CONCENTRATES:  24

ENVIRONMENT: 25
Rand study finds that industry is incorporating environmental concerns into corporate planning.

NIH GRADUATE SCHOOL:   27
Advisory committee has mixed reaction to graduate school plan.

GOVERNMENT INSIGHTS:   30
Attending scientific meetings in Cuba may be easier now, but customs agents can still mar reentry to U.S.

SCIENCE/TECHNOLOGY CONCENTRATES:  33

COVER STORY

WEIGHING IN ON OBESITY:   35
Complex array of chemicals that regulate body weight provides targets for weight-control drugs.

PROCESS CHEMISTRY:   45
Essential link between discovery research and commercial production poses continuing challenges.

"A GLIMPSE OF HELL":   53
Former naval officer/reporter investigated events preceding, during, and after the explosion on the USS Iowa.

PRELIMINARY PROGRAM:   59
Listing of technical symposia, educational, social, and special events for New Orleans; registration and housing forms.

  5 EDITOR'S PAGE
  6 LETTERS
  48  NEW PRODUCTS
 112 NEWSCRIPTS

Chemical & Engineering News
Copyright © 1999 American Chemical Society