Table of Contents

November 7, 2000
Volume 39, Issue 44
Pages 13295-13624
For Selected Content:

CURRENT TOPICS

Ion Channels, Permeation, and Electrostatics: Insight into the Function of KcsA

Benoît Roux, Simon Bernèche, and Wonpil Im
pp 13295–13306
Publication Date (Web): October 13, 2000 (Current Topics/Perspectives)
DOI: 10.1021/bi001567v

ACCELERATED PUBLICATIONS

Structure and Mechanism of Peptide Methionine Sulfoxide Reductase, an “Anti-Oxidation” Enzyme,

W. Todd Lowther, Nathan Brot, Herbert Weissbach, and Brian W. Matthews
pp 13307–13312
Publication Date (Web): October 13, 2000 (Accelerated Publication)
DOI: 10.1021/bi0020269

ARTICLES

Structure of a Murine Cytoplasmic Serine Hydroxymethyltransferase Quinonoid Ternary Complex:  Evidence for Asymmetric Obligate Dimers

Doletha M. E. Szebenyi, Xiaowen Liu, Irina A. Kriksunov, Patrick J. Stover, and Daniel J. Thiel
pp 13313–13323
Publication Date (Web): October 07, 2000 (Article)
DOI: 10.1021/bi000635a

Reaction Intermediate Analogues for Mandelate Racemase:  Interaction between Asn 197 and the α-Hydroxyl of the Substrate Promotes Catalysis

Martin St. Maurice and Stephen L. Bearne
pp 13324–13335
Publication Date (Web): October 14, 2000 (Article)
DOI: 10.1021/bi001144t

A Key Role in Catalysis for His89 of Adenylosuccinate Lyase of Bacillus subtilis

Jennifer L. Brosius and Roberta F. Colman
pp 13336–13343
Publication Date (Web): October 12, 2000 (Article)
DOI: 10.1021/bi001488j

Localization of the Cl-/HCO3- Anion Exchanger Binding Site to the Amino-Terminal Region of Carbonic Anhydrase II

John W. Vince, Uno Carlsson, and Reinhart A. F. Reithmeier
pp 13344–13349
Publication Date (Web): October 07, 2000 (Article)
DOI: 10.1021/bi0015111

Removal of the Four C-Terminal Glycine-Rich Repeats Enhances the Thermostability and Substrate Binding Affinity of Barley β-Amylase

Yue F. Ma, Jason K. Eglinton, D. Evan Evans, Sue J. Logue, and Peter Langridge
pp 13350–13355
Publication Date (Web): October 07, 2000 (Article)
DOI: 10.1021/bi000688s

Dynamics of the Metallo-β-Lactamase from Bacteroides fragilis in the Presence and Absence of a Tight-Binding Inhibitor

James J. A. Huntley, Sergio D. B. Scrofani, Michael J. Osborne, Peter E. Wright, and H. Jane Dyson
pp 13356–13364
Publication Date (Web): October 07, 2000 (Article)
DOI: 10.1021/bi001210r

Evaluation of the Utility of NMR Structures Determined from Minimal NOE-Based Restraints for Structure-Based Drug Design, Using MMP-1 as an Example

Xuemei Huang, Franklin Moy, and Robert Powers
pp 13365–13375
Publication Date (Web): October 10, 2000 (Article)
DOI: 10.1021/bi001658s

Dimer Formation through Domain Swapping in the Crystal Structure of the Grb2-SH2−Ac-pYVNV Complex

Nikolaus Schiering, Elena Casale, Paolo Caccia, Patrizia Giordano, and Carlo Battistini
pp 13376–13382
Publication Date (Web): October 14, 2000 (Article)
DOI: 10.1021/bi0012336

Use of the Parallax-Quench Method to Determine the Position of the Active-Site Loop of Cholesterol Oxidase in Lipid Bilayers

Xiaoyu Chen, David E. Wolfgang, and Nicole S. Sampson
pp 13383–13389
Publication Date (Web): October 04, 2000 (Article)
DOI: 10.1021/bi001407j

Modified Nucleoside Dependent Watson−Crick and Wobble Codon Binding by tRNALysUUU Species

Connie Yarian, Michal Marszalek, Elzbieta Sochacka, Andrzej Malkiewicz, Richard Guenther, Agnieszka Miskiewicz, and Paul F. Agris
pp 13390–13395
Publication Date (Web): October 10, 2000 (Article)
DOI: 10.1021/bi001302g

Functional Anticodon Architecture of Human tRNALys3 Includes Disruption of Intraloop Hydrogen Bonding by the Naturally Occurring Amino Acid Modification, t6A

John W. Stuart, Zofia Gdaniec, Richard Guenther, Michal Marszalek, Elzbieta Sochacka, Andrzej Malkiewicz, and Paul F. Agris
pp 13396–13404
Publication Date (Web): October 10, 2000 (Article)
DOI: 10.1021/bi0013039

Topology of Yeast RNA Polymerase II Subunits in Transcription Elongation Complexes Studied by Photoaffinity Cross-Linking

Christine I. Wooddell and Richard R. Burgess
pp 13405–13421
Publication Date (Web): October 10, 2000 (Article)
DOI: 10.1021/bi0014249

Structural Characterization of a Guanine−Quadruplex Ligand Complex

Martin A. Read and Stephen Neidle
pp 13422–13432
Publication Date (Web): October 10, 2000 (Article)
DOI: 10.1021/bi001584k

Functional Dissection of the Dimerization and Enzymatic Activities of Escherichia coli Nitrogen Regulator II and Their Regulation by the PII Protein

Peng Jiang, Mariette R. Atkinson, Chatchawan Srisawat, Quan Sun, and Alexander J. Ninfa
pp 13433–13449
Publication Date (Web): October 11, 2000 (Article)
DOI: 10.1021/bi000794u

The Escherichia coli PII Signal Transduction Protein Regulates the Activities of the Two-Component System Transmitter Protein NRII by Direct Interaction with the Kinase Domain of the Transmitter Module

Augen A. Pioszak, Peng Jiang, and Alexander J. Ninfa
pp 13450–13461
Publication Date (Web): October 11, 2000 (Article)
DOI: 10.1021/bi000795m

Sterols and Sphingolipids Strongly Affect the Growth of Fusion Pores Induced by the Hemagglutinin of Influenza Virus

Vladimir I. Razinkov and Fredric S. Cohen
pp 13462–13468
Publication Date (Web): October 13, 2000 (Article)
DOI: 10.1021/bi0012078

Mechanism of Annexin I-Mediated Membrane Aggregation

Eduard Bitto, Ming Li, Aleksey M. Tikhonov, Mark L. Schlossman, and Wonhwa Cho
pp 13469–13477
Publication Date (Web): October 10, 2000 (Article)
DOI: 10.1021/bi001275u

Coupling of Hydrogen Bonding to Chromophore Conformation and Function in Photoactive Yellow Protein

Ronald Brudler, Terrence E. Meyer, Ulrich K. Genick, Savitha Devanathan, Tammy T. Woo, David P. Millar, Klaus Gerwert, Michael A. Cusanovich, Gordon Tollin, and Elizabeth D. Getzoff
pp 13478–13486
Publication Date (Web): October 12, 2000 (Article)
DOI: 10.1021/bi0009946

Defining the Bilin Lyase Domain:  Lessons from the Extended Phytochrome Superfamily

Shu-Hsing Wu and J. Clark Lagarias
pp 13487–13495
Publication Date (Web): October 13, 2000 (Article)
DOI: 10.1021/bi001123z

Mutagenesis of Three Conserved Glu Residues in a Bacterial Homologue of the ND1 Subunit of Complex I Affects Ubiquinone Reduction Kinetics but Not Inhibition by Dicyclohexylcarbodiimide

Sari Kurki, Volker Zickermann, Marko Kervinen, Ilmo Hassinen, and Moshe Finel
pp 13496–13502
Publication Date (Web): October 12, 2000 (Article)
DOI: 10.1021/bi001134s

Kinetics and Activation Thermodynamics of Methane Monooxygenase Compound Q Formation and Reaction with Substrates

Brian J. Brazeau and John D. Lipscomb
pp 13503–13515
Publication Date (Web): October 13, 2000 (Article)
DOI: 10.1021/bi001473l

Binding of the Delta Subunit to Rod Phosphodiesterase Catalytic Subunits Requires Methylated, Prenylated C-Termini of the Catalytic Subunits

Terry A. Cook, Farideh Ghomashchi, Michael H. Gelb, Stephanie K. Florio, and Joseph A. Beavo
pp 13516–13523
Publication Date (Web): October 11, 2000 (Article)
DOI: 10.1021/bi001070l

Critical Role of a Subdomain of the N-Terminus of the V1a Vasopressin Receptor for Binding Agonists but Not Antagonists; Functional Rescue by the Oxytocin Receptor N-Terminus

Stuart R. Hawtin, Victoria J. Wesley, Rosemary A. Parslow, Smita Patel, and Mark Wheatley
pp 13524–13533
Publication Date (Web): October 10, 2000 (Article)
DOI: 10.1021/bi0013400

Identifying the Lipid−Protein Interface and Transmembrane Structural Transitions of the Torpedo Na,K-ATPase Using Hydrophobic Photoreactive Probes

Michael P. Blanton and Elizabeth A. McCardy
pp 13534–13544
Publication Date (Web): October 07, 2000 (Article)
DOI: 10.1021/bi0015461

Structure−Function Study and Anti-HIV Activity of Synthetic Peptide Analogues Derived from Viral Chemokine vMIP-II

Zhaowen Luo, Xuejun Fan, Naiming Zhou, Megumi Hiraoka, Jiansong Luo, Hideko Kaji, and Ziwei Huang
pp 13545–13550
Publication Date (Web): October 06, 2000 (Article)
DOI: 10.1021/bi000633q

Mutations of Serine 236−237 and Tyrosine 302 Residues in the Human Lipoxin A4 Receptor Intracellular Domains Result in Sustained Signaling

Yong Kang, Brunella Taddeo, George Varai, John Varga, and Stefano Fiore
pp 13551–13557
Publication Date (Web): October 13, 2000 (Article)
DOI: 10.1021/bi001196i

Evidence for a Second Nucleotide Binding Site in Rat Elongation Factor eEF-2 Specific for Adenylic Nucleotides

Philippe Gonzalo, Bruno Sontag, Jean-Pierre Lavergne, Jean-Michel Jault, and Jean-Paul Reboud
pp 13558–13564
Publication Date (Web): October 06, 2000 (Article)
DOI: 10.1021/bi000896k

Interaction of CBFα/AML/PEBP2α Transcription Factors with Nucleosomes Containing Promoter Sequences Requires Flexibility in the Translational Positioning of the Histone Octamer and Exposure of the CBFα Site

José Gutiérrez, José Sierra, Ricardo Medina, Marcia Puchi, María Imschenetzky, Andre van Wijnen, Jane Lian, Gary Stein, Janet Stein, and Martin Montecino
pp 13565–13574
Publication Date (Web): October 14, 2000 (Article)
DOI: 10.1021/bi0013896

Expression and Structural Characterization of the Recombinant Human Doppel Protein,

Ke Lu, Wen Wang, Zhiliang Xie, Boon-Seng Wong, Ruliang Li, Robert B. Petersen, Man-Sun Sy, and Shu G. Chen
pp 13575–13583
Publication Date (Web): October 11, 2000 (Article)
DOI: 10.1021/bi001523m

pH Dependence of Formation of a Partially Unfolded State of a Lys 73 → His Variant of Iso-1-cytochrome c:  Implications for the Alkaline Conformational Transition of Cytochrome c

Carma J. Nelson and Bruce E. Bowler
pp 13584–13594
Publication Date (Web): October 11, 2000 (Article)
DOI: 10.1021/bi0017778

Kinetics and Reactivity of the Flavin and Heme Cofactors of Cellobiose Dehydrogenase from Phanerochaete chrysosporium

Michael D. Cameron and Steven D. Aust
pp 13595–13601
Publication Date (Web): October 13, 2000 (Article)
DOI: 10.1021/bi000862c

Structural Preordering in the N-Terminal Region of Ribosomal Protein S4 Revealed by Heteronuclear NMR Spectroscopy

Eric W. Sayers, Resi B. Gerstner, David E. Draper, and Dennis A. Torchia
pp 13602–13613
Publication Date (Web): October 11, 2000 (Article)
DOI: 10.1021/bi0013391

Inhibitors of Abscisic Acid 8‘-Hydroxylase

Adrian J. Cutler, Patricia A. Rose, Timothy M. Squires, Mary K. Loewen, Angela C. Shaw, J. Wilson Quail, Joan E. Krochko, and Suzanne R. Abrams
pp 13614–13624
Publication Date (Web): October 07, 2000 (Article)
DOI: 10.1021/bi0014453
For Selected Content:
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