Table of Contents

April 2003
Volume 16, Issue 4
Pages 433-570
For Selected Content:

ARTICLES

A Fluorimetric Microplate Assay for Detection and Quantitation of Toxins Causing Paralytic Shellfish Poisoning

Maria Carmen Louzao, Mercedes Rodriguez Vieytes, Ana Garcia Cabado, Juan Manuel Vieites Baptista de Sousa, and Luis Miguel Botana
pp 433–438
Publication Date (Web): March 01, 2003 (Article)
DOI: 10.1021/tx025574r

Hypochlorous Acid-Mediated Oxidation of Lipid Components and Antioxidants Present in Low-Density Lipoproteins:  Absolute Rate Constants, Product Analysis, and Computational Modeling

David I. Pattison, Clare L. Hawkins, and Michael J. Davies
pp 439–449
Publication Date (Web): March 06, 2003 (Article)
DOI: 10.1021/tx025670s

Inhibition of Cytochrome P450 2D6:  Structure−Activity Studies Using a Series of Quinidine and Quinine Analogues

J. Matthew Hutzler, Gregory S. Walker, and Larry C. Wienkers
pp 450–459
Publication Date (Web): March 06, 2003 (Article)
DOI: 10.1021/tx025674x

Low Concentrations of Arsenic Induce Vascular Endothelial Growth Factor and Nitric Oxide Release and Stimulate Angiogenesis In Vitro

Ying-Hsien Kao, Chia-Li Yu, Louis W. Chang, and Hsin-Su Yu
pp 460–468
Publication Date (Web): March 22, 2003 (Article)
DOI: 10.1021/tx025652a

Effect of Nitroreduction on the Alkylating Reactivity and Cytotoxicity of the 2,4-Dinitrobenzamide-5-aziridine CB 1954 and the Corresponding Nitrogen Mustard SN 23862:  Distinct Mechanisms of Bioreductive Activation

Nuala A. Helsby, S. James Wheeler, Frederik B. Pruijn, Brian D. Palmer, Shangjin Yang, William A. Denny, and William R. Wilson
pp 469–478
Publication Date (Web): March 05, 2003 (Article)
DOI: 10.1021/tx025662b

Extraction and Purification of Depurinated Benzo[a]pyrene-Adducted DNA Bases from Human Urine by Immunoaffinity Chromatography Coupled with HPLC and Analysis by LC/Quadrupole Ion-Trap MS

Sumitra Bhattacharya, Damon C. Barbacci, Meilan Shen, Jia-nuo Liu, and George P. Casale
pp 479–486
Publication Date (Web): March 11, 2003 (Article)
DOI: 10.1021/tx020060d

Carbon Dioxide Modulation of Peroxynitrite-Induced Mutagenesis of the supF Gene in pSP189

Burcak Pamir and Gerald N. Wogan
pp 487–492
Publication Date (Web): March 07, 2003 (Article)
DOI: 10.1021/tx020093t

Stability of the Putative Neurotoxin Tryptamine-4,5-dione

Monika Z. Wrona, Xiang-Rong Jiang, Yashige Kotake, and Glenn Dryhurst
pp 493–501
Publication Date (Web): March 14, 2003 (Article)
DOI: 10.1021/tx020080f

Nitrite-Induced Nitration Pathways of Retinoic Acid, 5,6-Epoxyretinoic Acid, and Their Esters under Mildly Acidic Conditions:  Toward a Reappraisal of Retinoids as Scavengers of Reactive Nitrogen Species

Lucia Panzella, Paola Manini, Orlando Crescenzi, Alessandra Napolitano, and Marco d'Ischia
pp 502–511
Publication Date (Web): March 20, 2003 (Article)
DOI: 10.1021/tx0256836

Model Studies on Protein Side Chain Modification by 4-Oxo-2-nonenal

Wei-Han Zhang, Jiyun Liu, Guozhang Xu, Quan Yuan, and Lawrence M. Sayre
pp 512–523
Publication Date (Web): March 22, 2003 (Article)
DOI: 10.1021/tx020105a

Uranyl Acetate Causes DNA Single Strand Breaks In Vitro in the Presence of Ascorbate (Vitamin C)

Monica Yazzie, Shania L. Gamble, Edgar R. Civitello, and Diane M. Stearns
pp 524–530
Publication Date (Web): March 22, 2003 (Article)
DOI: 10.1021/tx025685q

Dityrosine Cross-Linked Aβ Peptides:  Fibrillar β-Structure in Aβ(1-40) Is Conducive to Formation of Dityrosine Cross-Links but a Dityrosine Cross-Link in Aβ(8-14) Does Not Induce β-Structure

Joshua C. Yoburn, Wenqiang Tian, Justin O. Brower, James S. Nowick, Charles G. Glabe, and David L. Van Vranken
pp 531–535
Publication Date (Web): March 22, 2003 (Article)
DOI: 10.1021/tx025666g

Mass Mapping Sites of Nitration in Tyrosine Hydroxylase:  Random vs Selective Nitration of Three Tyrosine Residues

Chad R. Borges, Donald M. Kuhn, and J. Throck Watson
pp 536–540
Publication Date (Web): March 19, 2003 (Article)
DOI: 10.1021/tx0256681

K-ras Gene Sequence Effects on the Formation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)−DNA Adducts

Rebecca Ziegel, Anthony Shallop, Roger Jones, and Natalia Tretyakova
pp 541–550
Publication Date (Web): March 22, 2003 (Article)
DOI: 10.1021/tx025619o

Covalent Binding of Leukotriene A4 to DNA and RNA

Joseph A. Hankin, David N. M. Jones, and Robert C. Murphy
pp 551–561
Publication Date (Web): March 28, 2003 (Article)
DOI: 10.1021/tx034018+

Photochemical Properties of Ofloxacin Involved in Oxidative DNA Damage:  A Comparison with Rufloxacin

M. Consuelo Cuquerella, Francisco Boscá, Miguel A. Miranda, Alessandra Belvedere, Alfio Catalfo, and Guido de Guidi
pp 562–570
Publication Date (Web): March 29, 2003 (Article)
DOI: 10.1021/tx034006o
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