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Table of Contents
November 2000
Volume 77, Issue 11
Pages 1383-1528
About the Cover:
The crystal structure of egg-white lysozyme complexed with N-acetylchitotriose is shown to highlight the recognition of the carbohydrate by the protein. In this complex, a tryptophan residue from the enzyme is interacting with the trisaccharide through CH-p interactions. These and other p-type interactions have been shown to be important intra- and intermolecular forces in determining the structure of proteins and protein-ligand complexes. The article Teaching Noncovalent Interactions in the Biochemistry Curriculum through Molecular Visualization: The Search for p Interactions, by James R. Cox, describes how molecular visualization can be used to teach p-type and other noncovalent interactions in the biochemistry curriculum.
