Articles ASAP (As Soon As Publishable)

ASAP articles are edited and published online ahead of print.

ACS AuthorChoice indicates the article is freely available through sponsorship by the author or related funding agency. More about this program.
For Selected Content:

November 17, 2009

Process Development and Pilot-Scale Synthesis of New Cyclization Conditions of Substituted Phenylacetamides to Tetrahydroisoquinoline-2-ones Using Eaton’s Reagent

Luckner G. Ulysse, Qiang Yang, Mark D. McLaws, Daniel K. Keefe, Peter R. Guzzo and Brian P. Haney
Publication Date (Web): November 17, 2009 (Communication to Editor)
DOI: 10.1021/op9002533

Book Review: Dynamic Stereochemistry of Chiral Compounds - Principles and Applications

Trevor Laird
Publication Date (Web): November 17, 2009 (Book Review)
DOI: 10.1021/op9002856

November 16, 2009

The Development of a New Manufacturing Route to the Novel Anticonvulsant, SB-406725A

Matthew D. Walker, Benjamin I. Andrews, Andrew J. Burton, Luke D. Humphreys, Gary Kelly, Mark B. Schilling and Peter W. Scott
Publication Date (Web): November 16, 2009 (Article)
DOI: 10.1021/op9002054

November 10, 2009

Development of a Multikilogram Synthesis of a Chiral Epoxide Precursor to a CCR1 Antagonist. Use of in Situ Monitoring for Informed Optimisation via Fragile Intermediates

Debra Ainge, James E. M. Booker, Nicholas Pedge, Rhona Sinclair, Chris Sleigh, Marijan tefinovi, Luis-Manuel Vaz and Edward Way
Publication Date (Web): November 10, 2009 (Article)
DOI: 10.1021/op900172t

November 6, 2009

Application of Quality by Design Principles to Support Development of a Control Strategy for the Control of Genotoxic Impurities in the Manufacturing Process of a Drug Substance

Zadeo Cimarosti, Fernando Bravo, Paul Stonestreet, Francesco Tinazzi, Orsola Vecchi and Giulio Camurri
Publication Date (Web): November 6, 2009 (Article)
DOI: 10.1021/op900242x

Investigation of Synthetic Routes to a Key Benzopyran Intermediate of a 5HT4 Agonist

Geracimos Rassias, Neil G. Stevenson, Neil R. Curtis, John M. Northall, Matthew Gray, Jeremy C. Prodger and Andrew J. Walker
Publication Date (Web): November 6, 2009 (Article)
DOI: 10.1021/op900188v

July 24, 2009

Optimisation of Permanganate Oxidation and Suzuki−Miyaura Coupling Steps in the Synthesis of a Nav1.8 Sodium Channel Modulator

M. Jonathan Fray, Adam T. Gillmore, Melanie S. Glossop, David J. McManus, Ian B. Moses, Cline F.B. Praquin, Keith A. Reeves and Lisa R. Thompson
Publication Date (Web): July 24, 2009 (Article)
DOI: 10.1021/op900092h

July 8, 2009

Oxidation of Hexafluoropropylene with Oxygen to Hexafluoropropylene Oxide

Agnieszka Wrblewska, Eugeniusz Milchert and Egbert Meissner
Publication Date (Web): July 8, 2009 (Article)
DOI: 10.1021/op900151p

June 4, 2009

“Dark” Singlet Oxygenation of β-Citronellol: A Key Step in the Manufacture of Rose Oxide

Paul L. Alsters, Walther Jary, Vronique Nardello-Rataj and Jean-Marie Aubry
Publication Date (Web): June 4, 2009 (Article)
DOI: 10.1021/op900076g

May 18, 2009

Industrial Oxidations with Organocatalyst TEMPO and Its Derivatives

Rosaria Ciriminna and Mario Pagliaro
Publication Date (Web): May 18, 2009 (Review)
DOI: 10.1021/op900059x

May 11, 2009

Hydrogen Peroxide Oxidation of Phosphite Triesters in Oligonucleotide Syntheses

Raymond J. Cvetovich
Publication Date (Web): May 11, 2009 (Communication to Editor)
DOI: 10.1021/op900044z
For Selected Content:
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