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February 9, 2010

Stereoselective Synthesis of cis- and trans-2,3-Disubstituted Tetrahydrofurans via Oxonium−Prins Cyclization: Access to the Cordigol Ring System

Alan C. Spivey, Luca Laraia, Andrew R. Bayly, Henry S. Rzepa and Andrew J. P. White
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol9024259

Diphosphine-Catalyzed Mixed Double-Michael Reaction: A Unified Synthesis of Indolines, Dihydropyrrolopyridines, Benzimidazolines, Tetrahydroquinolines, Tetrahydroisoquinolines, Dihydrobenzo-1,4-oxazines, and Dihydrobenzo-3,1-oxazines

Vardhineedi Sriramurthy and Ohyun Kwon
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol100078w

Diastereo- and Enantioselective Synthesis of α,γ-Diaminobutyric Acid Derivatives via Cu-Catalyzed Asymmetric Michael Reaction

Qing Li, Chang-Hua Ding, Xue-Long Hou and Li-Xin Dai
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol100060t

Enantioselective Friedel−Crafts Reaction of β-Trifluoromethylated Acrylates with Pyrroles and Its Application to the Synthesis of Trifluorinated Heliotridane

Yiyong Huang, Etsuko Tokunaga, Satoru Suzuki, Motoo Shiro and Norio Shibata
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol100171z

A Facile and Mild Synthesis of Enamides using a Gold-Catalyzed Nucleophilic Addition to Allenamides

Marc C. Kimber
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol1001494

Remarkable Effects of P-Perfluorophenyl Group on the Synthesis of Core-Modified Phosphaporphyrinoids and Phosphadithiasapphyrin

Takashi Nakabuchi, Yoshihiro Matano and Hiroshi Imahori
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol100114j

Gold(I)-Catalyzed Highly Regio- and Stereoselective Decarboxylative Amination of Allylic N-Tosylcarbamates via Base-Induced Aza-Claisen Rearrangement in Water

Dong Xing and Dan Yang
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol100056f

Iron-Catalyzed Regio- and Stereoselective Substitution of γ,δ-Epoxy-α,β-unsaturated Esters and Amides with Grignard Reagents

Takeshi Hata, Rie Bannai, Mamoru Otsuki and Hirokazu Urabe
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol100022w

Synthesis of γ,δ-Unsaturated Glycolic Acids via Sequenced Brook and Ireland−Claisen Rearrangements

Daniel C. Schmitt and Jeffrey S. Johnson
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol9029353

Synthesis and Biological Evaluation of Heteroanalogues of Kotalanol and De-O-Sulfonated Kotalanol

Sankar Mohan, Kumarasamy Jayakanthan, Ravindranath Nasi, Douglas A. Kuntz, David R. Rose and B. Mario Pinto
Publication Date (Web): February 9, 2010 (Letter)
DOI: 10.1021/ol100080m

February 8, 2010

Palladium-Catalyzed Direct Cyanation of Indoles with K4[Fe(CN)6]

Guobing Yan, Chunxiang Kuang, Yan Zhang and Jianbo Wang
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol1000439

Low Catalyst Loadings in Olefin Metathesis: Synthesis of Nitrogen Heterocycles by Ring-Closing Metathesis

Kevin M. Kuhn, Timothy M. Champagne, Soon Hyeok Hong, Wen-Hao Wei, Andrew Nickel, Choon Woo Lee, Scott C. Virgil, Robert H. Grubbs and Richard L. Pederson
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol9029808

Syntheses and Biological Evaluation of Irciniastatin A and the C1−C2 Alkyne Analogue

Tsubasa Watanabe, Takamichi Imaizumi, Takumi Chinen, Yoko Nagumo, Masatoshi Shibuya, Takeo Usui, Naoki Kanoh and Yoshiharu Iwabuchi
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol1000389

Reactions of Oxetan-3-tert-butylsulfinimine for the Preparation of Substituted 3-Aminooxetanes

Philip J. Hamzik and Jason D. Brubaker
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol100119e

Stereoselective Synthesis of a Monocyclic Peloruside A Analogue

Christoph W. Wullschleger, Jrg Gertsch and Karl-Heinz Altmann
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol100123p

Au/Ag-Catalyzed Intramolecular Ring-Opening of Vinylidene-cyclopropanes (VDCPs): An Easy Access to Functional Tetrahydropyrans

Wei Li, Wei Yuan, Surech Pindi, Min Shi and Guigen Li
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol902832s

Efficient Synthesis of Hangman Porphyrins

Dilek K. Dogutan, D. Kwabena Bediako, Thomas S. Teets, Matthias Schwalbe and Daniel G. Nocera
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol902947h

Evaluation of the Biosynthetic Proposal for the Synthesis of Marineosins A and B

Leslie N. Aldrich, Eric S. Dawson and Craig W. Lindsley
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol100034p

Synthesis of Polycyclic Nitrogen Heterocycles via Alkene Aminopalladation/Carbopalladation Cascade Reactions

Danielle M. Schultz and John P. Wolfe
Publication Date (Web): February 8, 2010 (Letter)
DOI: 10.1021/ol100033s

February 5, 2010

Total Synthesis of Chloptosin, a Potent Apoptosis-Inducing Cyclopeptide

Shun-Ming Yu, Wen-Xu Hong, Yuan Wu, Chun-Long Zhong and Zhu-Jun Yao
Publication Date (Web): February 5, 2010 (Letter)
DOI: 10.1021/ol100135a

New Modes for the Osmium-Catalyzed Oxidative Cyclization

Timothy J. Donohoe, Peter J. Lindsay-Scott, Jeremy S. Parker and Cedric K. A. Callens
Publication Date (Web): February 5, 2010 (Letter)
DOI: 10.1021/ol100046a

Total Synthesis and Determination of the Absolute Configuration of (−)-Idesolide

Hiroyuki Yamakoshi, Masatoshi Shibuya, Masaki Tomizawa, Yuji Osada, Naoki Kanoh and Yoshiharu Iwabuchi
Publication Date (Web): February 5, 2010 (Letter)
DOI: 10.1021/ol9029676

February 4, 2010

Total Synthesis of 10-Isocyano-4-cadinene and Determination of Its Absolute Configuration

Keisuke Nishikawa, Hiroshi Nakahara, Yousuke Shirokura, Yasuyuki Nogata, Erina Yoshimura, Taiki Umezawa, Tatsufumi Okino and Fuyuhiko Matsuda
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol9027336

Unsymmetrical Triangular Schiff Base Macrocycles with Cone Conformations

Jian Jiang and Mark J. MacLachlan
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol100028s

[4 + 2] Cycloaddition Reactions Catalyzed by a Chiral Oxazaborolidinium Cation. Reaction Rates and Diastereo-, Regio-, and Enantioselectivity Depend on Whether Both Bonds Are Formed Simultaneously

Santanu Mukherjee and E. J. Corey
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol100032u

Tetra-ortho-Substituted Biaryls through Palladium-Catalyzed Suzuki−Miyaura Couplings with a Diaminochlorophosphine Ligand

Lutz Ackermann, Harish K. Potukuchi, Andreas Althammer, Robert Born and Peter Mayer
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol1000186

Transmetalation of Z-Telluroenynes: Stereoselective Synthesis of Z-Enynols and Their Application in Palladium-Catalyzed Cyclization

Caroline C. Schneider, Helton Caldeira, Bibiana M. Gay, Davi F. Back and Gilson Zeni
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol902896x

Organocatalytic Asymmetric Formal [4 + 2] Cycloaddition for the Synthesis of Spiro[4-cyclohexanone-1,3′-oxindoline] Derivatives in High Optical Purity

Qiang Wei and Liu-Zhu Gong
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol100020v

C3-Symmetric Chiral Trisimidazoline: Design and Application to Organocatalyst

Kenichi Murai, Shunsuke Fukushima, Shoko Hayashi, Yusuke Takahara and Hiromichi Fujioka
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol902958m

Asymmetric Binary-Acid Catalysis with Chiral Phosphoric Acid and MgF2: Catalytic Enantioselective Friedel−Crafts Reactions of β,γ-Unsaturated α-Ketoesters

Jian Lv, Xin Li, Long Zhong, Sanzhong Luo and Jin-Pei Cheng
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol1000928

Two-Step Alkylation of Single-Walled Carbon Nanotubes: Substituent Effect on Sidewall Functionalization

Yutaka Maeda, Takaaki Kato, Tadashi Hasegawa, Masahiro Kako, Takeshi Akasaka, Jing Lu and Shigeru Nagase
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol100006n

“Clicktophycin-52”: A Bioactive Cryptophycin-52 Triazole Analogue

Markus Nahrwold, Tobias Bogner, Stefan Eissler, Spart Verma and Norbert Sewald
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol1000473

Efficient Discovery of Fluorescent Chemosensors Based on a Biarylpyridine Scaffold

Sergey A. Malashikhin, Kim K. Baldridge and Nathaniel S. Finney
Publication Date (Web): February 4, 2010 (Letter)
DOI: 10.1021/ol902902m

February 2, 2010

Spirodiepoxide Strategy to the C Ring of Pectenotoxin 4: Synthesis of the C1−C19 Sector

Sipak Joyasawal, Stephen D. Lotesta, N. G. Akhmedov and Lawrence J. Williams
Publication Date (Web): February 2, 2010 (Letter)
DOI: 10.1021/ol902984e

[14]Annulene: Cis/Trans Isomerization via Two-Twist and Nondegenerate Planar Bond Shifting and Mbius Conformational Minima

Tobechi Okoronkwo, Phuong T. Nguyen, Claire Castro and William L. Karney
Publication Date (Web): February 2, 2010 (Letter)
DOI: 10.1021/ol100025j

CuCl/CCl4-Promoted Convenient Synthesis of Sulfonyl Amidines from Tertiary Amines and Sulfonyl Azides

Xiaoliang Xu, Zhichuang Ge, Dongping Cheng, Lei Ma, Chunshan Lu, Qunfeng Zhang, Nan Yao and Xiaonian Li
Publication Date (Web): February 2, 2010 (Letter)
DOI: 10.1021/ol1000236

Rh(I)-Catalyzed Decarboxylative Transformations of Arenecarboxylic Acids: Ligand- and Reagent-Controlled Selectivity toward Hydrodecarboxylation or Heck−Mizoroki Products

Zhong-Ming Sun, Jing Zhang and Pinjing Zhao
Publication Date (Web): February 2, 2010 (Letter)
DOI: 10.1021/ol100001b

February 1, 2010

Asymmetric [4 + 3] Cycloadditions between Benzofuranyldiazoacetates and Dienes: Formal Synthesis of (+)-Frondosin B

Jeremy P. Olson and Huw M. L. Davies
Publication Date (Web): February 1, 2010 (Addition/Correction)
DOI: 10.1021/ol100111w

Improving Catalytic Activity by Synergic Effect between Base and Acid Pairs in Hierarchically Porous Chitosan@Titania Nanoreactors

Abdelkrim El Kadib, Karine Molvinger, Mosto Bousmina and Daniel Brunel
Publication Date (Web): February 1, 2010 (Letter)
DOI: 10.1021/ol9029319

Rhodium Carbenoid Approach for Introduction of 4-Substituted (Z)-Pent-2-enoates into Sterically Encumbered Pyrroles and Indoles

Yajing Lian and Huw M. L. Davies
Publication Date (Web): February 1, 2010 (Letter)
DOI: 10.1021/ol9028385

January 29, 2010

Pd-Catalyzed Decarboxylative Cross Coupling of Potassium Polyfluorobenzoates with Aryl Bromides, Chlorides, and Triflates

Rui Shang, Qing Xu, Yuan-Ye Jiang, Yan Wang and Lei Liu
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol100008q

Improved Synthesis of the Two-Photon Caging Group 3-Nitro-2-Ethyldibenzofuran and Its Application to a Caged Thymidine Phosphoramidite

Hrvoje Lusic, Rajendra Uprety and Alexander Deiters
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol902807q

Nickel-Catalyzed Asymmetric Ullmann Coupling for the Synthesis of Axially Chiral Tetra-ortho-Substituted Biaryl Dials

Wen-Wen Chen, Qian Zhao, Ming-Hua Xu and Guo-Qiang Lin
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol1000632

A Rationally Designed Fluorescence Turn-On Probe for the Gold(III) Ion

Jung Ho Do, Ha Na Kim, Juyoung Yoon, Jong Seung Kim and Hae-Jo Kim
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol902860f

An in-Ketocyclophane

Qian Qin, Joel T. Mague and Robert A. Pascal, Jr.
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol9028572

Stereoselective Synthesis of the C25−C36 Segment of Arenicolides A and B: Determination of the Configuration of the Trisubstituted Epoxide

Shinji Nagumo, Taeko Nakano, Kyomi Hata, Megumi Mizukami and Masaaki Miyashita
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol902750e

Ruthenium-Catalyzed trans-Hydrogermylation of Alkynes: Formation of 2,5-Disubstituted Germoles through Double trans-Hydrogermylation of 1,3-Diynes

Takanori Matsuda, Sho Kadowaki, Yoshiyuki Yamaguchi and Masahiro Murakami
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol1000445

7,7′-Diureido-2,2′-diindolylmethanes: Anion Receptors Effective in a Highly Competitive Solvent, Methanol

Paweł Dydio, Tomasz Zieliski and Janusz Jurczak
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol1000395

Melotenine A, a Cytotoxic Monoterpenoid Indole Alkaloid from Melodinus tenuicaudatus

Tao Feng, Yan Li, Ya-Ping Liu, Xiang-Hai Cai, Yuan-Yuan Wang and Xiao-Dong Luo
Publication Date (Web): January 29, 2010 (Letter)
DOI: 10.1021/ol1000022

January 28, 2010

Stereocontrolled and Efficient Total Synthesis of (−)-Stephanotic Acid Methyl Ester and (−)-Celogentin C

Weimin Hu, Fengying Zhang, Zhengren Xu, Qiang Liu, Yuxin Cui and Yanxing Jia
Publication Date (Web): January 28, 2010 (Letter)
DOI: 10.1021/ol902944f

Arisandilactone A, a New Triterpenoid from the Fruits of Schisandra arisanensis

Yuan-Bin Cheng, Tzu-Ching Liao, I-Wen Lo, Yu-Chen Chen, Yuh-Chi Kuo, Shun-Ying Chen, Ching-Te Chien and Ya-Ching Shen
Publication Date (Web): January 28, 2010 (Letter)
DOI: 10.1021/ol100024r

Plumisclerin A, a Diterpene with a New Skeleton from the Soft Coral Plumigorgia terminosclera

Mara Jess Martn, Rogelio Fernndez, Andrs Francesch, Philippe Amade, Susana S. de Matos-Pita, Fernando Reyes and Carmen Cuevas
Publication Date (Web): January 28, 2010 (Letter)
DOI: 10.1021/ol902802h

Scalable Synthesis of Cryptophane-1.1.1 and its Functionalization

Tnin Traor, La Delacour, Sbastien Garcia-Argote, Patrick Berthault, Jean-Christophe Cintrat and Bernard Rousseau
Publication Date (Web): January 28, 2010 (Letter)
DOI: 10.1021/ol902952h

N2-Modified 2-aminopurine ribonucleosides as minor-groove-modulating adenosine replacements in duplex RNA

Hayden Peacock, Olena Maydanovych and Peter A. Beal
Publication Date (Web): January 28, 2010 (Letter)
DOI: 10.1021/ol100019r

January 27, 2010

A New Highly Selective, Ratiometric and Colorimetric Fluorescence Sensor for Cu2+ with a Remarkable Red Shift in Absorption and Emission Spectra Based on Internal Charge Transfer

Shyamaprosad Goswami, Debabrata Sen and Nirmal Kumar Das
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol9029066

Highly Enantioselective Intramolecular Cyanoamidation: (+)-Horsfiline, (−)-Coerulescine, and (−)-Esermethole

Venkata Jaganmohan Reddy and Christopher J. Douglas
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol902949d

Rh2(OAc)4-AgOTf Cooperative Catalysis in Cyclization/Three-Component Reactions for Concise Synthesis of 1,2-Dihydroisoquinolines

Zhenqiu Guo, Mei Cai, Jun Jiang, Liping Yang and Wenhao Hu
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol902409u

An Efficient Synthesis of (±)-Trichostatic Acid and Analogues: A New Route to (±)-Trichostatin A

Anamitra Chatterjee, Joshua Richer, Tyler Hulett, Vijaya Bhaskara Reddy Iska, Olaf Wiest and Paul Helquist
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol9029116

Isolation of Ugi Four-Component Condensation Primary Adducts: A Straightforward Route to Isocoumarins

Cristina Faggi, Mara Garca-Valverde, Stefano Marcaccini and Gloria Menchi
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol9028622

Direct Asymmetric Allylic Alkylation of Butenolides with Morita−Baylis−Hillman Carbonates

Hai-Lei Cui, Ji-Rong Huang, Jie Lei, Zhao-Feng Wang, Shi Chen, Li Wu and Ying-Chun Chen
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol100014m

Wittig Olefination between Phosphine, Aldehyde, and Allylic Carbonate: A General Method for Stereoselective Synthesis of Trisubstituted 1,3-Dienes with Highly Variable Substituents

Rong Zhou, Chunzhang Wang, Haibin Song and Zhengjie He
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol902956y

Synthesis of Fish Antifreeze Neoglycopeptides Using Microwave-Assisted “Click Chemistry”

Nicole Miller, Geoffrey M. Williams and Margaret A. Brimble
Publication Date (Web): January 27, 2010 (Addition/Correction)
DOI: 10.1021/ol1001208

A Mild Hydrothermal Route to Fix Carbon Dioxide to Simple Carboxylic Acids

Chao He, Ge Tian, Ziwei Liu and Shouhua Feng
Publication Date (Web): January 27, 2010 (Letter)
DOI: 10.1021/ol9025414

January 26, 2010

Tandem Ir-Catalyzed Allylic Substitution Reaction of Allyl Sulfinates and Isomerization

Qing-Long Xu, Li-Xin Dai and Shu-Li You
Publication Date (Web): January 26, 2010 (Letter)
DOI: 10.1021/ol902873q

Stereoselective Synthesis of Highly Functionalized α-Diazo-β-ketoalkanoates via Catalytic One-Pot Mukaiyama-Aldol Reactions

Lei Zhou and Michael P. Doyle
Publication Date (Web): January 26, 2010 (Letter)
DOI: 10.1021/ol902872y

Convergent Synthesis of α-Ketoamide Inhibitors of Pin1

Guoyan G. Xu and Felicia A. Etzkorn
Publication Date (Web): January 26, 2010 (Letter)
DOI: 10.1021/ol9027013

Merobatzelladines A and B, Anti-Infective Tricyclic Guanidines from a Marine Sponge Monanchora sp

Shunsuke Takishima, Aki Ishiyama, Masato Iwatsuki, Kazuhiko Otoguro, Haruki Yamada, Satoshi mura, Hirotsugu Kobayashi, Rob W. M. van Soest and Shigeki Matsunaga
Publication Date (Web): January 26, 2010 (Addition/Correction)
DOI: 10.1021/ol1001522

January 25, 2010

Benzotetramisole-Catalyzed Dynamic Kinetic Resolution of Azlactones

Xing Yang, Guojian Lu and Vladimir B. Birman
Publication Date (Web): January 25, 2010 (Letter)
DOI: 10.1021/ol902969j

Synthesis of Isoindigo-Based Oligothiophenes for Molecular Bulk Heterojunction Solar Cells

Jianguo Mei, Kenneth R. Graham, Romain Stalder and John R. Reynolds
Publication Date (Web): January 25, 2010 (Letter)
DOI: 10.1021/ol902512x

Allylic Oxidations of Terminal Olefins Using a Palladium Thioether Catalyst

William H. Henderson, Christopher T. Check, Nicolas Proust and James P. Stambuli
Publication Date (Web): January 25, 2010 (Letter)
DOI: 10.1021/ol902905w

Palladium-Catalyzed Chemoselective Monoarylation of Hydrazides for the Synthesis of [1,2,4]Triazolo[4,3-a]pyridines

Andreas Reichelt, James R. Falsey, Robert M. Rzasa, Oliver R. Thiel, Michal M. Achmatowicz, Robert D. Larsen and Dawei Zhang
Publication Date (Web): January 25, 2010 (Letter)
DOI: 10.1021/ol902868q

Nickel-Catalyzed Efficient and Practical Suzuki−Miyaura Coupling of Alkenyl and Aryl Carbamates with Aryl Boroxines

Li Xu, Bi-Jie Li, Zhen-Hua Wu, Xing-Yu Lu, Bing-Tao Guan, Bi-Qin Wang, Ke-Qing Zhao and Zhang-Jie Shi
Publication Date (Web): January 25, 2010 (Letter)
DOI: 10.1021/ol9029534

Highly Diastereoselective Zinc-Catalyzed Propargylation of tert-Butanesulfinyl Imines

Daniel R. Fandrick, Courtney S. Johnson, Keith R. Fandrick, Jonathan T. Reeves, Zhulin Tan, Heewon Lee, Jinhua J. Song, Nathan K. Yee and Chris H. Senanayake
Publication Date (Web): January 25, 2010 (Letter)
DOI: 10.1021/ol9028258

January 22, 2010

Quorum-Sensing-Regulated Bactobolin Production by Burkholderia thailandensis E264

Mohammad R. Seyedsayamdost, Josephine R. Chandler, Joshua A. V. Blodgett, Patricia S. Lima, Breck A. Duerkop, Ken-Ichi Oinuma, E. Peter Greenberg and Jon Clardy
Publication Date (Web): January 22, 2010 (Letter)
DOI: 10.1021/ol902751x
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Why Are Perfluorocyclobutadiene and Some Other (CF)nq Rings Non-Planar?

Judy I. Wu, Francesco A. Evangelista and Paul von Ragu Schleyer
Publication Date (Web): January 22, 2010 (Letter)
DOI: 10.1021/ol902866n

A Novel, Versatile D→BCD Steroid Construction Strategy, Illustrated by the Enantioselective Total Synthesis of Estrone

Vincent Foucher, Benedetta Guizzardi, Marinus B. Groen, Mark Light and Bruno Linclau
Publication Date (Web): January 22, 2010 (Letter)
DOI: 10.1021/ol902638w

Unexpected Reactivity of o-Nitrosophenol with RCH2Br: C−H Bond Cleavage and Annulation to Benzoxazoles and Benzoxazines (R = Alkynyl)

Wei Yao and Dejian Huang
Publication Date (Web): January 22, 2010 (Letter)
DOI: 10.1021/ol902812q

First Efficient Synthesis of Fluorinated Glycidic Esters from Ketones

Grald Lemonnier, Ludivine Zoute, Jean-Charles Quirion and Philippe Jubault
Publication Date (Web): January 22, 2010 (Letter)
DOI: 10.1021/ol902903v

Cyclic Ketals of Tartaric Acid: Simple and Tunable Reagents for the Determination of the Absolute Configuration of Primary Amines

You-Jin Shim and Kihang Choi
Publication Date (Web): January 22, 2010 (Letter)
DOI: 10.1021/ol902942k

January 21, 2010

Arylchlorogermanes/TBAF/“Moist” Toluene: A Promising Combination for Pd-Catalyzed Germyl-Stille Cross-Coupling

Zun-Ting Zhang, Jean-Philippe Pitteloud, Laura Cabrera, Yong Liang, Myrdich Toribio and Stanislaw F. Wnuk
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol9028918

A Versatile Enantioselective Synthesis of Barrenazines

Miguel Pea-Lpez, M. Montserrat Martnez, Luis A. Sarandeses and Jos Prez Sestelo
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902920u

Selectivity Algorithm for the Formation of Two Cryptand/Paraquat Catenanes

Ming Liu, Shijun Li, Menglong Hu, Feng Wang and Feihe Huang
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol9028463

Selective Synthesis of Eight-Membered Cyclic Ureas by the [6 + 2] Cycloaddition Reaction of 2-Vinylazetidines and Electron-Deficient Isocyanates

Shunsuke Koya, Kenichi Yamanoi, Ryu Yamasaki, Isao Azumaya, Hyuma Masu and Shinichi Saito
Publication Date (Web): January 21, 2010 (Addition/Correction)
DOI: 10.1021/ol100069q

Unsaturated Lactams: New Inputs for Povarov-Type Multicomponent Reactions

Esther Vicente-Garca, Federica Catti, Rosario Ramn and Rodolfo Lavilla
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902913j

First Enantiocontrolled Formal Synthesis of (+)-Neovibsanin B, A Neurotrophic Diterpenoid

Tomoyuki Esumi, Takehiro Mori, Ming Zhao, Masao Toyota and Yoshiyasu Fukuyama
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902960n

Asymmetric Synthesis of Substituted Homotropinones from N-Sulfinyl β-Amino Ketone Ketals. (−)-Euphococcinine and (−)-Adaline

Franklin A. Davis and Ram Edupuganti
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902910w

Functionalization of Multilayer Fullerenes (Carbon Nano-Onions) using Diazonium Compounds and “Click” Chemistry

Kevin Flavin, Manuel N. Chaur, Luis Echegoyen and Silvia Giordani
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902939f

Catalytic Asymmetric Total Synthesis of Tangutorine

Tetsuhiro Nemoto, Eri Yamamoto, Robert Franzn, Takashi Fukuyama, Riliga Wu, Toshihiko Fukamachi, Hiroshi Kobayashi and Yasumasa Hamada
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902929a

Synthesis of Benzoxazolones from Nitroarenes or Aryl Halides

Achim Porzelle, Michael D. Woodrow and Nicholas C. O. Tomkinson
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902885j

Fluorescence Turn-On Sensor for Cyanide Based on a Cobalt(II)−Coumarinylsalen Complex

Jae Han Lee, A Reum Jeong, Ik-Soo Shin, Hae-Jo Kim and Jong-In Hong
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902852g

Chirality Holds the Key for Potent Inhibition of the Botulinum Neurotoxin Serotype A Protease

G. Neil Stowe, Peter ilhr, Mark S. Hixon, Nicholas R. Silvaggi, Karen N. Allen, Scott T. Moe, Alan R. Jacobson, Joseph T. Barbieri and Kim D. Janda
Publication Date (Web): January 21, 2010 (Letter)
DOI: 10.1021/ol902820z

January 20, 2010

Rapid Assembly of the Salvileucalin B Norcaradiene Core

Sergiy Levin, Roger R. Nani and Sarah E. Reisman
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol902848k

Synthesis of β-Aminoketones and Construction of Highly Substituted 4-Piperidones by Mannich Reaction Induced by Persistent Radical Cation Salts

Xiao-Dong Jia, Xiao-E Wang, Cai-Xia Yang, Cong-De Huo, Wen-Juan Wang, Yan Ren and Xi-Cun Wang
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol9027978

Mechanistic Insights into the Reactions of Co(III) Salens with Diazoacetates

Scott K. Koehn, Scott Gronert and Jamal T. Aldajaei
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol902682f

Asymmetric Aza-Mannich Addition of Oxazolones to N-Tosyl Aldimines: Synthesis of Chiral α-Disubstituted α,β-Diamino Acids

Xiaodong Liu, Leijiao Deng, Xianxing Jiang, Wenjin Yan, Chunliang Liu and Rui Wang
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol902916s

Rapid Decarboxylative Allylation of Nitroalkanes

Alexander J. Grenning and Jon A. Tunge
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol902828p

Selective Transformation of a Crown Ether/sec-Ammonium Salt-Type Rotaxane to N-Alkylated Rotaxanes

Sakiko Suzuki, Kazuko Nakazono and Toshikazu Takata
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol902719m

Chemoselectivity of the Ru-Catalyzed Cycloisomerization Reaction for the Synthesis of Dihydropyrans; Application to the Synthesis of l-Forosamine

Michael J. Zacuto, Daisuke Tomita, Zainab Pirzada and Feng Xu
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol9026667

Efficient Synthesis of α-Ketoamides via 2-Acyl-5-aminooxazoles by Reacting Acyl Chlorides and α-Isocyanoacetamides

Riccardo Mossetti, Tracey Pirali, Gian Cesare Tron and Jieping Zhu
Publication Date (Web): January 20, 2010 (Letter)
DOI: 10.1021/ol902894p

January 19, 2010

Chemoselective Bromodeboronation of Organotrifluoroborates Using Tetrabutylammonium Tribromide: Application in (Z)-Dibromoalkene Syntheses

Min-Liang Yao, Marepally Srinivasa Reddy, Li Yong, Ingrid Walfish, David W. Blevins and George W. Kabalka
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol9027144

Asymmetric Allylation, Crotylation, and Cinnamylation of N-Heteroaryl Hydrazones

Miriam Inbar Feske, Alexander Buitrago Santanilla and James L. Leighton
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol9026864

Caged Chalcogens: Theoretical Studies on a Tetracoordinated Oxonium Dication and Its Higher Homologues

Tobias F. Schneider and Daniel B. Werz
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol902904z

General Methodology for the Preparation of 2,5-Disubstituted-1,3-oxazoles

David R. Williams and Liangfeng Fu
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol902833p

Enantiospecific Synthesis of the Cubitane Skeleton

Elisabeth Schttner, Maren Wiechoczek, Peter G. Jones and Thomas Lindel
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol902854t

Photocycloaddition of Enynones (4-Acylbut-1-en-3-ynes) to Alkenes

Inga Inhlsen and Paul Margaretha
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol902827s

Palladium-Catalyzed Three-Component [3 + 2] Cycloaddition of Propargyl Trifluoroacetates, Ethylidene Malononitriles, and Allyltributylstannane

Shirong Lu, Tienan Jin, Ming Bao and Yoshinori Yamamoto
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol9029275

Burkholdines 1097 and 1229, Potent Antifungal Peptides from Burkholderia ambifaria 2.2N

Kamilia A. Tawfik, Peter Jeffs, Brian Bray, George Dubay, Joseph O. Falkinham, III, Mostafa Mesbah, Diaa Youssef, Sherief Khalifa and Eric W. Schmidt
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol9029269

Highly Enantio- and Diastereoselective Mannich Reactions of Glycine Schiff Bases with in situ Generated N-Boc-imines Catalyzed by a Cinchona Alkaloid Thiourea

Haile Zhang, Salahuddin Syed and Carlos F. Barbas, III
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol902722y

Acetylenic Phenyldithiafulvene: A Versatile Synthon for TTFV-Based Macromolecules

Guang Chen, Ilias Mahmud, Louise N. Dawe and Yuming Zhao
Publication Date (Web): January 19, 2010 (Letter)
DOI: 10.1021/ol9026683

January 15, 2010

Psidials A−C, Three Unusual Meroterpenoids from the Leaves of Psidium guajava L

Hui-Zheng Fu, Yong-Ming Luo, Chuang-Jun Li, Jing-Zhi Yang and Dong-Ming Zhang
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol9024869

Palladium-Catalyzed Direct Arylations, Alkenylations, and Benzylations through C−H Bond Cleavages with Sulfamates or Phosphates as Electrophiles

Lutz Ackermann, Sebastian Barfsser and Jola Pospech
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol9028034

Gold(I)-Catalyzed Ring Expansions of Unactivated Alkynylcyclopropanes to (E)-2-Alkylidenecyclobutanamines in the Presence of Sulfonamides

Siyu Ye and Zhi-Xiang Yu
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol9028786

Facile Preparation of 3-Substituted Benzisothiazoles from o-Mercaptoacylphenones

Nelmi O. Devarie-Baez and Ming Xian
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol9028447

Synthesis of (±)-Bistellettadine A

Min Yu, Susan S. Pochapsky and Barry B. Snider
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol902895e

Superelectrophilic Activation in Superacid HF/SbF5 and Synthesis of Benzofused Sultams

Fei Liu, Agns Martin-Mingot, Marie-Paule Jouannetaud, Fabien Zunino and Sbastien Thibaudeau
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol9029287

Enantioselective Total Synthesis of (+)-Conicol via Cascade Three-Component Organocatalysis

Bor-Cherng Hong, Prakash Kotame, Chih-Wei Tsai and Ju-Hsiou Liao
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol902840x

Total Synthesis of (−)-Exiguolide

Cyril Cook, Xavier Guinchard, Frdric Liron and Emmanuel Roulland
Publication Date (Web): January 15, 2010 (Letter)
DOI: 10.1021/ol902829e

January 14, 2010

Synthesis and Identification of a Trimethylenemethane Derivative π-Extended with Three Pyridinyl Radicals

Kouzou Matsumoto, Daisuke Inokuchi, Yasukazu Hirao, Hiroyuki Kurata, Kazunobu Sato, Takeji Takui and Takashi Kubo
Publication Date (Web): January 14, 2010 (Letter)
DOI: 10.1021/ol902937k

A Novel Approach to 3-Methylindoles by a Heck/Cyclization/Isomerization Process

Carl A. Baxter, Ed Cleator, Mahbub Alam, Antony J. Davies, Adrian Goodyear and Michael O’Hagan
Publication Date (Web): January 14, 2010 (Letter)
DOI: 10.1021/ol902636v

Phosphaalkenes in π-Conjugation with Acetylenic Arenes

Xue-Li Geng, Qi Hu, Bernhard Schfer and Sascha Ott
Publication Date (Web): January 14, 2010 (Letter)
DOI: 10.1021/ol902688n

January 7, 2010

Formal Synthesis of Belactosin A and Hormaomycin via a Diastereoselective Intramolecular Cyclopropanation of an α-Nitro Diazoester

Sbastien F. Vanier, Guillaume Larouche, Ryan P. Wurz and Andr B. Charette
Publication Date (Web): January 7, 2010 (Letter)
DOI: 10.1021/ol9026528
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