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“Click” Modification of Silica Surfaces and Glass Microfluidic Channels

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Department of Mechanical Science and Engineering and Department of Chemistry, University of Illinois at UrbanaChampaign, Urbana, Illinois 61801
Cite this: Anal. Chem. 2007, 79, 4, 1661–1667
Publication Date (Web):December 22, 2006
https://doi.org/10.1021/ac061824n
Copyright © 2007 American Chemical Society

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    Abstract

    This paper demonstrates a chemical surface modification method for covalent attachment of various polymers by using silane-based “click” chemistry on silica surfaces and within glass microchannels suitable for CE systems. Modified surfaces are characterized by contact angle measurements, X-ray photoelectron spectroscopy, and Fourier transform infrared-attenuated total reflection spectroscopy. Electroosmotic flow (EOF) measurements in modified and unmodified channels are provided. Spectroscopic and transport data show that various polymers can be covalently attached to glass surfaces with a measurable change in EOF.

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     Department of Mechanical Science and Engineering.

     Department of Chemistry.

    *

     To whom correspondence should be addressed. E-mail:  [email protected]; [email protected].

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    9. Justin M. Notestein, Christian Canlas, John Siegfried, and Jeffrey S. Moore . Covalent Grafting of m-Phenylene-Ethynylene Oligomers to Oxide Surfaces. Chemistry of Materials 2010, 22 (18) , 5319-5327. https://doi.org/10.1021/cm1016245
    10. Hidenori Mizuno and Jillian M. Buriak. Building Upon Patterned Organic Monolayers Produced via Catalytic Stamp Lithography. ACS Applied Materials & Interfaces 2010, 2 (8) , 2301-2307. https://doi.org/10.1021/am100348f
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    32. A. Kuznetsov, E. Kuznetsov, E. Rybachek, K. Puchnin, V. Grudtsov, A. Saurov. Development of an Integrated CMOS-Microfluidics for Bioelectronic Nose. 2018, 1-4. https://doi.org/10.1109/ICSENS.2018.8589687
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    41. Kaushik K. Rangharajan, Shaurya Prakash. Surface-Modified Microfluidics and Nanofluidics. 2016, 3997-4002. https://doi.org/10.1007/978-94-017-9780-1_395
    42. Shaurya Prakash, Harvey A. Zambrano, Kaushik K. Rangharajan, Emily Rosenthal-Kim, Nicolas Vasquez, A. T. Conlisk. Electrokinetic transport of monovalent and divalent cations in silica nanochannels. Microfluidics and Nanofluidics 2016, 20 (1) https://doi.org/10.1007/s10404-015-1667-0
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    47. Kaushik K. Rangharajan, Shaurya Prakash. Surface-Modified Microfluidics and Nanofluidics. 2015, 1-7. https://doi.org/10.1007/978-94-007-6178-0_395-2
    48. Kaushik K. Rangharajan, Kwang J. Kwak, A. T. Conlisk, Yan Wu, Shaurya Prakash. Effect of surface modification on interfacial nanobubble morphology and contact line tension. Soft Matter 2015, 11 (26) , 5214-5223. https://doi.org/10.1039/C5SM00583C
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    51. Byung Hang Ha, Kang Soo Lee, Jin Ho Jung, Hyung Jin Sung. Three-dimensional hydrodynamic flow and particle focusing using four vortices Dean flow. Microfluidics and Nanofluidics 2014, 17 (4) , 647-655. https://doi.org/10.1007/s10404-014-1346-6
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    54. Zheng Zhang, Ming-Luan Chen, Xiao-Dong Cheng, Zhi-Guo Shi, Bi-Feng Yuan, Yu-Qi Feng. A facile approach for the polymer grafting of silica based on tandem reversible addition fragmentation chain transfer/click chemistry and its application in high performance liquid chromatography. Journal of Chromatography A 2014, 1351 , 96-102. https://doi.org/10.1016/j.chroma.2014.05.054
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    57. Shaurya Prakash, Junghoon Yeom. Interfaces in Microfluidic and Nanofluidic Systems. 2014, 39-86. https://doi.org/10.1016/B978-1-4377-4469-9.00003-2
    58. Shaurya Prakash, Junghoon Yeom. Lab-on-a-Chip and Fluid Manipulation Applications. 2014, 171-239. https://doi.org/10.1016/B978-1-4377-4469-9.00005-6
    59. Jérémie Asselin, Carl Roy, Denis Boudreau, Younès Messaddeq, Rihab Bouchareb, Patrick Mathieu. Supported core–shell nanobiosensors for quantitative fluorescence imaging of extracellular pH. Chem. Commun. 2014, 50 (89) , 13746-13749. https://doi.org/10.1039/C4CC06075J
    60. Claudia Poloni, Wiktor Szymanski, Ben L. Feringa. Photo-controlled deactivation of immobilised lipase. Chem. Commun. 2014, 50 (84) , 12645-12648. https://doi.org/10.1039/C4CC06087C
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    63. Audrey Marechal, Racha El‐Debs, Vincent Dugas, Claire Demesmay. Is click chemistry attractive for separation sciences?. Journal of Separation Science 2013, 36 (13) , 2049-2062. https://doi.org/10.1002/jssc.201300231
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    66. M. Teresa Fernández‐Abedul, Isabel Álvarez‐Martos, Francisco Javier García Alonso, Agustín Costa‐García. Improving the Separation in Microchip Electrophoresis by Surface Modification. 2013, 95-125. https://doi.org/10.1002/9781118530009.ch6
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    74. Manoj Gaur, Mayurika Goel, L. Sridhar, Tara Devi S. Ashok, S. Prabhakar, P. Dureja, P. Raghunathan, S. V. Eswaran. Synthesis, characterization, and antifungal activity of biaryl-based bis(1,2,3-triazoles) using click chemistry. Monatshefte für Chemie - Chemical Monthly 2012, 143 (2) , 283-288. https://doi.org/10.1007/s00706-011-0652-x
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    78. Peter K. B. Palomaki, Peter H. Dinolfo. Structural Analysis of Porphyrin Multilayer Films on ITO Assembled Using Copper(I)-Catalyzed Azide–Alkyne Cycloaddition by ATR IR. ACS Applied Materials & Interfaces 2011, 3 (12) , 4703-4713. https://doi.org/10.1021/am201125p
    79. Xiaozhong Jin, N. R. Aluru. Gated transport in nanofluidic devices. Microfluidics and Nanofluidics 2011, 11 (3) , 297-306. https://doi.org/10.1007/s10404-011-0796-3
    80. Mathias Bækbo Andersen, Henrik Bruus, Jaydeep P. Bardhan, Sumita Pennathur. Streaming current and wall dissolution over 48h in silica nanochannels. Journal of Colloid and Interface Science 2011, 360 (1) , 262-271. https://doi.org/10.1016/j.jcis.2011.04.011
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    82. Anders E. Daugaard, Thomas S. Hansen, Niels B. Larsen, Søren Hvilsted. Microwave assisted click chemistry on a conductive polymer film. Synthetic Metals 2011, 161 (9-10) , 812-816. https://doi.org/10.1016/j.synthmet.2011.02.005
    83. Peter K. B. Palomaki, Alexandra Krawicz, Peter H. Dinolfo. Thickness, Surface Morphology, and Optical Properties of Porphyrin Multilayer Thin Films Assembled on Si(100) Using Copper(I)-Catalyzed Azide−Alkyne Cycloaddition. Langmuir 2011, 27 (8) , 4613-4622. https://doi.org/10.1021/la104499b
    84. Malinda Salim, Sally L. McArthur, S. Vaidyanathan, Phillip C. Wright. Towards proteomics-on-chip: The role of the surface. Mol. BioSyst. 2011, 7 (1) , 101-115. https://doi.org/10.1039/C005236A
    85. Miriam Keppeler, Nicola Hüsing. Space-confined click reactions in hierarchically organized silica monoliths. New J. Chem. 2011, 35 (3) , 681-690. https://doi.org/10.1039/C0NJ00645A
    86. Roxana-Viorela Ostaci, Denis Damiron, Samer Al Akhrass, Yves Grohens, Eric Drockenmuller. Poly(ethylene glycol) brushes grafted to silicon substrates by click chemistry: influence of PEG chain length, concentration in the grafting solution and reaction time. Polym. Chem. 2011, 2 (2) , 348-354. https://doi.org/10.1039/C0PY00251H
    87. Suyan Qiu, Sen Gao, Xi Zhu, Zhenyu Lin, Bin Qiu, Guonan Chen. Development of ultra-high sensitive and selective electrochemiluminescent sensor for copper(ii) ions: a novel strategy for modification of gold electrode using click chemistry. The Analyst 2011, 136 (8) , 1580. https://doi.org/10.1039/c0an00846j
    88. Hua Lu, Shulin Qi, John Mack, Zhifang Li, Jianping Lei, Nagao Kobayashi, Zhen Shen. Facile Hg2+ detection in water using fluorescent self-assembled monolayers of a rhodamine-based turn-on chemodosimeter formed via a “click” reaction. Journal of Materials Chemistry 2011, 21 (29) , 10878. https://doi.org/10.1039/c1jm11319d
    89. Nanwen Li, Wolfgang H. Binder. Click-chemistry for nanoparticle-modification. Journal of Materials Chemistry 2011, 21 (42) , 16717. https://doi.org/10.1039/c1jm11558h
    90. Shaurya Prakash, Mehmet B. Karacor. Characterizing stability of “click” modified glass surfaces to common microfabrication conditions and aqueous electrolyte solutions. Nanoscale 2011, 3 (8) , 3309. https://doi.org/10.1039/c1nr10261c
    91. Jongmin Noh, Hee Chan Kim, Taek Dong Chung. Biosensors in Microfluidic Chips. 2011, 117-152. https://doi.org/10.1007/128_2011_143
    92. Yong Wang, David James Young, Timothy Thatt Yang Tan, Siu-Choon Ng. “Click” preparation of hindered cyclodextrin chiral stationary phases and their efficient resolution in high performance liquid chromatography. Journal of Chromatography A 2010, 1217 (50) , 7878-7883. https://doi.org/10.1016/j.chroma.2010.10.059
    93. Zhaowei Zhang, Xiaojun Feng, Fei Xu, Xin Liu, Bi‐Feng Liu. “Click” chemistry‐based surface modification of poly(dimethylsiloxane) for protein separation in a microfluidic chip. ELECTROPHORESIS 2010, 31 (18) , 3129-3136. https://doi.org/10.1002/elps.201000208
    94. Yong Wang, David J. Young, Timothy Thatt Yang Tan, Siu-Choon Ng. “Click” immobilized perphenylcarbamated and permethylated cyclodextrin stationary phases for chiral high-performance liquid chromatography application. Journal of Chromatography A 2010, 1217 (31) , 5103-5108. https://doi.org/10.1016/j.chroma.2010.06.003
    95. Peter K. B. Palomaki, Peter H. Dinolfo. A Versatile Molecular Layer-by-Layer Thin Film Fabrication Technique Utilizing Copper(I)-Catalyzed Azide−Alkyne Cycloaddition. Langmuir 2010, 26 (12) , 9677-9685. https://doi.org/10.1021/la100308j
    96. S. Belhousse, R. Boukherroub, S. Szunerits, N. Gabouze, A. Keffous, S. Sam, A. Benaboura. Electrochemical grafting of poly(3-hexylthiophene) on porous silicon for gas sensing. Surface and Interface Analysis 2010, 42 (6-7) , 1041-1045. https://doi.org/10.1002/sia.3284
    97. Basit Yameen, Mubarak Ali, Marta Álvarez, Reinhard Neumann, Wolfgang Ensinger, Wolfgang Knoll, Omar Azzaroni. A facile route for the preparation of azide-terminated polymers. “Clicking” polyelectrolyte brushes on planar surfaces and nanochannels. Polym. Chem. 2010, 1 (2) , 183-192. https://doi.org/10.1039/B9PY00201D
    98. Claudia Haensch, Stephanie Hoeppener, Ulrich S. Schubert. Chemical modification of self-assembled silane based monolayers by surface reactions. Chemical Society Reviews 2010, 39 (6) , 2323. https://doi.org/10.1039/b920491a
    99. Yuanfu Zhang, Baoxin Li, Chunli Xu. Visual detection of ascorbic acid via alkyne–azide click reaction using gold nanoparticles as a colorimetric probe. The Analyst 2010, 135 (7) , 1579. https://doi.org/10.1039/c0an00056f
    100. Himabindu Nandivada, Joerg Lahann. Copper‐Catalyzed ‘Click’ Chemistry for Surface Engineering. 2009, 291-307. https://doi.org/10.1002/9780470748862.ch12
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