The Long Neglected Cycloidal Mass AnalyzerClick to copy article linkArticle link copied!
- Elettra L. PiacentinoElettra L. PiacentinoDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Elettra L. Piacentino
- Rafael Bento SerpaRafael Bento SerpaDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Rafael Bento Serpa
- Kathleen L. HorvathKathleen L. HorvathDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Kathleen L. Horvath
- Raul VyasRaul VyasDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Raul Vyas
- Tanouir AlouiTanouir AlouiDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Tanouir Aloui
- Charles B. ParkerCharles B. ParkerDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Charles B. Parker
- James B. CarlsonJames B. CarlsonEngineering and Applied Physics Division, RTI International, Research Triangle Park, North Carolina 27709, United StatesMore by James B. Carlson
- Justin KeoghJustin KeoghDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United StatesMore by Justin Keogh
- Roger P. SperlineRoger P. SperlineDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United StatesMore by Roger P. Sperline
- Maria L. SartorelliMaria L. SartorelliDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesDepartamento de Física, Universidade Federal de Santa Catarina, Campus Universitário Trindade, 88040-000 Florianópolis, Santa Catarina BrazilMore by Maria L. Sartorelli
- Brian R. StonerBrian R. StonerDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Brian R. Stoner
- Michael E. GehmMichael E. GehmDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Michael E. Gehm
- Jeffrey T. GlassJeffrey T. GlassDepartment of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Jeffrey T. Glass
- M. Bonner DentonM. Bonner DentonDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United StatesMore by M. Bonner Denton
- Jason J. Amsden*Jason J. Amsden*Phone: 919-348-1574. Email: [email protected]Department of Electrical and Computer Engineering, Duke University, Durham, North Carolina 27708, United StatesMore by Jason J. Amsden
Abstract
In 1938, Walker Bleakney and John A. Hipple first described the cycloidal mass analyzer as the only mass analyzer configuration capable of “perfect” ion focusing. Why has their geometry been largely neglected for many years and how might it earn a respectable place in the world of modern chemical analysis? This Perspective explores the properties of the cycloidal mass analyzer and identifies the lack of suitable ion array detectors as a significant reason why cycloidal mass analyzers are not widely used. The recent development of capacitive transimpedance amplifier array detectors can enable several techniques using cycloidal mass analyzers including spatially coded apertures and single particle mass analysis with a “virtual-slit”, helping the cycloidal mass analyzer earn a respectable place in chemical analysis.
Cited By
This article is cited by 4 publications.
- Tanouir Aloui, Raul Vyas, Scarlett Francini, Rafael Bento Serpa, Kathleen L. Horvath, Justin Keogh, Charles B. Parker, M. Bonner Denton, Jeffrey T. Glass, Michael E. Gehm, Jason J. Amsden. Spectral Reconstruction Improvement in a Cycloidal Coded-Aperture Mass Spectrometer. Journal of the American Society for Mass Spectrometry 2024, 35
(5)
, 855-861. https://doi.org/10.1021/jasms.3c00421
- Tanouir Aloui, Rafael Bento Serpa, Nabil Abboud, Kathleen L. Horvath, Justin Keogh, Charles B. Parker, Jennifer C. Stern, M. Bonner Denton, Maria Luisa Sartorelli, Jeffrey T. Glass, Michael E. Gehm, Jason J. Amsden. A super‐resolution proof of concept in a cycloidal coded aperture miniature mass spectrometer. Rapid Communications in Mass Spectrometry 2023, https://doi.org/10.1002/rcm.9477
- Kathleen L. Horvath, Elettra L. Piacentino, Rafael Bento Serpa, Tanouir Aloui, Raul Vyas, Yuriy Zhilichev, Jesko von Windheim, Maria Luisa Sartorelli, Charles B. Parker, M. Bonner Denton, Michael E. Gehm, Jeffrey T. Glass, Jason J. Amsden. Design considerations for a cycloidal mass analyzer using a focal plane array detector. Journal of Mass Spectrometry 2022, 57
(7)
https://doi.org/10.1002/jms.4874
- Rafael Bento Serpa, Elettra L. Piacentino, Kathleen L. Horvath, Tanouir Aloui, Yuriy Zhilichev, Charles B. Parker, Jeffrey T. Glass, Scott B. Tilden, Justin A. Keogh, Robert Kingston, Roger P. Sperline, M. Bonner Denton, Jason J. Amsden. Virtual-slit focusing in a cycloidal mass spectrometer – A proof of concept. International Journal of Mass Spectrometry 2021, 470 , 116706. https://doi.org/10.1016/j.ijms.2021.116706
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