Novel Ru(bpy)2(cpaphen)2+/TPrA/TiO2 Ternary ECL System: An Efficient Platform for the Detection of Glutathione with Mn2+ as Substitute TargetClick to copy article linkArticle link copied!
- Rui ZhangRui ZhangKey Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by Rui Zhang
- Xia ZhongXia ZhongKey Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by Xia Zhong
- An-Yi ChenAn-Yi ChenKey Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by An-Yi Chen
- Jia-Li LiuJia-Li LiuKey Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by Jia-Li Liu
- Sheng-Kai LiSheng-Kai LiKey Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by Sheng-Kai Li
- Ya-Qin ChaiYa-Qin ChaiKey Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by Ya-Qin Chai
- Ying Zhuo*Ying Zhuo*Tel.: +86 23 68253172. Fax: +86 23 68253172. E-mail: [email protected] (Y.Z.).Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by Ying Zhuo
- Ruo YuanRuo YuanKey Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. ChinaMore by Ruo Yuan
Abstract
A sensitive electrochemiluminescence (ECL) biosensor was developed for glutathione (GSH) detection based on a novel Ru(bpy)2(cpaphen)2+/TPrA/TiO2 ternary ECL system with Mn2+ as substitute target for signal amplification. Specifically, the TiO2 nanoneedles (TiO2 NNs) were used as the coreaction accelerator for the first time to promote the oxidation process of coreactant tripropylamine (TPrA) in the anode and significantly increase the ECL signal of Ru(bpy)2(cpaphen)2+ for an amplified initial signal. Meanwhile, a novel target conversion strategy for GSH was developed by reducing MnO2 nanosheets to Mn2+ as a substitute target, which played the role of a coenzyme factor for cleaving DNA double strands intercalated with Ru(bpy)2(cpaphen)2+ to markedly weaken initial signal. As a result, the novel “on–off” biosensor achieved a sensitive detection of GSH range from 5 μM to 215 μM with a detection limit of 0.33 μM. Importantly, the proposed strategy enriched the application of Ru complex and TPrA ECL system in bioanalytical applications, and provided a new signal amplification strategy for bioactive small molecules.
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(40)
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(37)
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(14)
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(2)
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(37)
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(31)
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(19)
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(4)
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(2)
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(50)
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(44)
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(30)
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(30)
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(7)
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(6)
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(4)
, 2090-2096. https://doi.org/10.1021/acs.analchem.0c03836
- Cheng Ma, Yue Cao, Xiaodan Gou, Jun-Jie Zhu. Recent Progress in Electrochemiluminescence Sensing and Imaging. Analytical Chemistry 2020, 92
(1)
, 431-454. https://doi.org/10.1021/acs.analchem.9b04947
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(21)
, 14117-14124. https://doi.org/10.1021/acs.analchem.9b03990
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(15)
, 10258-10265. https://doi.org/10.1021/acs.analchem.9b02404
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2
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(49)
https://doi.org/10.1002/smll.202406374
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(10)
https://doi.org/10.1007/s00604-024-06686-6
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ii
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(29)
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- Lihong Gao, Yitian Huang, Huizhu Ren, Sisi Chen, Shupei Zhang, Hong Dai. Nanocomplexes with anchored
Ru
bpy
3
2
+
-tetraethylene pentamine electrochemiluminescence system: Self-enhanced coupled photothermal strategy detection of thyroglobulin. Journal of Electroanalytical Chemistry 2023, 947 , 117767. https://doi.org/10.1016/j.jelechem.2023.117767
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(39)
https://doi.org/10.1002/ange.202308950
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(39)
https://doi.org/10.1002/anie.202308950
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(3)
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(5)
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(15)
, 7198-7204. https://doi.org/10.1039/D3NJ00178D
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3
2+
/HEPES System and Detection of Iodide Anions**. ChemistrySelect 2023, 8
(5)
https://doi.org/10.1002/slct.202204363
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3
2+
encapsulated zeolite imidazole metal organic framework. Chemical Communications 2022, 58
(86)
, 12114-12117. https://doi.org/10.1039/D2CC04270C
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3
2+
encapsulated by MIL-NH
2
-101(Al) nanocomposites. Journal of Materials Chemistry B 2022, 10
(38)
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- Linlin Song, Wenqiang Gao, Qinru Han, Yiping Huang, Lin Cui, Chun-yang Zhang. Construction of an aggregation-induced electrochemiluminescent sensor based on an aminal-linked covalent organic framework for sensitive detection of glutathione in human serum. Chemical Communications 2022, 58
(75)
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(3)
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(7)
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(17)
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(12)
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2
nanoreactors for monitoring cellular GSH levels. Nanoscale 2022, 14
(15)
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(2)
, 302-309. https://doi.org/10.1002/elan.202100287
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(9)
https://doi.org/10.1007/s00604-021-04957-0
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(16)
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(2)
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(9)
, 2743. https://doi.org/10.3390/molecules26092743
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3
perovskite nanocrystals for self-enhanced electrochemiluminescence in aqueous media. Nanoscale 2020, 12
(13)
, 7321-7329. https://doi.org/10.1039/D0NR00179A
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(2)
https://doi.org/10.1007/s41061-020-0291-y
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- Zhu Han, Danyang Nan, Huan Yang, Qianqian Sun, Shuang Pan, Hui Liu, Xiaoli Hu. Carbon quantum dots based ratiometric fluorescence probe for sensitive and selective detection of Cu2+ and glutathione. Sensors and Actuators B: Chemical 2019, 298 , 126842. https://doi.org/10.1016/j.snb.2019.126842
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- Atsuko Konishi, Shigehiko Takegami, Tatsuya Kitade. A Molecularly Imprinted Polymer-modified Potentiometric Sensor for the Detection of Glutathione. Analytical Sciences 2019, 35
(10)
, 1111-1115. https://doi.org/10.2116/analsci.19P166
- Jing Lu, Ling Wang, Xia Xu, Xiangxiang Qin, Xia Qiu, Zhu Yinggui. Electrochemiluminescence and analytical applications of terbium thiophene carboxylic acid complexes. Analytical Methods 2019, 11
(29)
, 3727-3735. https://doi.org/10.1039/C9AY01062A
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