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    Solubility of Benzoic Acid and Aspirin in Pure Solvents Using Focused Beam Reflective Measurement
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    † Solid State Pharmaceutical Cluster, School of Chemical and Bioprocess Engineering, University College Dublin, Belfield Dublin 4, Ireland
    *E-mail: [email protected]. Telephone: +353-1-715-1954. Fax: +353-1-716-1177.
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    Journal of Chemical & Engineering Data

    Cite this: J. Chem. Eng. Data 2016, 61, 1, 594–601
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    https://doi.org/10.1021/acs.jced.5b00746
    Published December 23, 2015
    Copyright © 2015 American Chemical Society
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    Abstract

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    The solubility of benzoic acid and acetylsalicylic acid is reported in varied pure solvents over a range of 275.39–327.03 K and 275.12–327.91 K for benzoic acid and aspirin, respectively, using the polythermal method with a heating rate of 0.1 K/min that was combined with the Lasentec focused beam reflective measurement to determine the saturation point of the solutions. The results were correlated using a modified van’t Hoff equation that fitted the solubility with a 2 K interval over a temperature range of 278.15–323.15 K. The results from the fitting equation were in good agreement with the experimental data.

    Copyright © 2015 American Chemical Society

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    This article is cited by 17 publications.

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    Journal of Chemical & Engineering Data

    Cite this: J. Chem. Eng. Data 2016, 61, 1, 594–601
    Click to copy citationCitation copied!
    https://doi.org/10.1021/acs.jced.5b00746
    Published December 23, 2015
    Copyright © 2015 American Chemical Society
    Request reuse permissions

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