ACS Publications. Most Trusted. Most Cited. Most Read
High-Temperature Behavior of Early Life Membrane Models

OR SEARCH CITATIONS

My Activity
Publications

Figure 1Loading Img
Download Hi-Res ImageDownload to MS-PowerPointCite This:Langmuir 2020, 36, 45, 13516-13526
    Article

    High-Temperature Behavior of Early Life Membrane Models
    Click to copy article linkArticle link copied!

    Other Access OptionsSupporting Information (1)

    Langmuir

    Cite this: Langmuir 2020, 36, 45, 13516–13526
    Click to copy citationCitation copied!
    https://doi.org/10.1021/acs.langmuir.0c02258
    Published November 4, 2020
    Copyright © 2020 American Chemical Society
    Request reuse permissions

    Abstract

    Click to copy section linkSection link copied!
    Abstract Image

    Origin of life scenarios generally assume an onset of cell formation in terrestrial hot springs or in the deep oceans close to hot vents, where energy was available for non-enzymatic reactions. Membranes of the protocells had therefore to withstand extreme conditions different from what is found on the Earth surface today. We present here an exhaustive study of temperature stability up to 80 °C of vesicles formed by a mixture of short-chain fatty acids and alcohols, which are plausible candidates for membranes permitting the compartmentalization of protocells. We confirm that the presence of alcohol has a strong structuring and stabilizing impact on the lamellar structures. Moreover and most importantly, at a high temperature (> 60 °C), we observe a conformational transition in the vesicles, which results from vesicular fusion. Because all the most likely environments for the origin of life involve high temperatures, our results imply the need to take into account such a transition and its effect when studying the behavior of a protomembrane model.

    Copyright © 2020 American Chemical Society

    Subjects

    what are subjects

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. Add or change your institution or let them know you’d like them to include access.

    Supporting Information

    Click to copy section linkSection link copied!

    The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.langmuir.0c02258.

    • Equations for the SANS model form factors, preliminary sample screening data, full list of parameters used for fits/simulations, and annexes (PDF)

    Terms & Conditions

    Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses). Permission may be obtained from ACS for other uses through requests via the RightsLink permission system: http://pubs.acs.org/page/copyright/permissions.html.

    Cited By

    Click to copy section linkSection link copied!
    Citation Statements
    Explore this article's citation statements on scite.ai
    powered by  Scite

    This article is cited by 16 publications.

    1. Abigail C. Dommer, Nicholas A. Wauer, Kyle J. Angle, Aakash Davasam, Patiemma Rubio, Man Luo, Clare K. Morris, Kimberly A. Prather, Vicki H. Grassian, Rommie E. Amaro. Revealing the Impacts of Chemical Complexity on Submicrometer Sea Spray Aerosol Morphology. ACS Central Science 2023, 9 (6) , 1088-1103. https://doi.org/10.1021/acscentsci.3c00184
    2. Zachary R. Cohen, Zoe R. Todd, David C. Catling, Roy A. Black, Sarah L. Keller. Prebiotic Vesicles Retain Solutes and Grow by Micelle Addition after Brief Cooling below the Membrane Melting Temperature. Langmuir 2022, 38 (44) , 13407-13413. https://doi.org/10.1021/acs.langmuir.2c01842
    3. Pawan Kumar, Dániel Sebők, Ákos Kukovecz, Dezső Horváth, Ágota Tóth. Hierarchical Self-Assembly of Metal-Ion-Modulated Chitosan Tubules. Langmuir 2021, 37 (43) , 12690-12696. https://doi.org/10.1021/acs.langmuir.1c02097
    4. . A Survey of the Battlefield for the Origin of Life. 2024, 411-580. https://doi.org/10.1002/9781119901228.ch11
    5. Silvia Holler, Stuart Bartlett, Richard J. G. Löffler, Federica Casiraghi, Claro Ignacio Sainz Diaz, Julyan H. E. Cartwright, Martin M. Hanczyc. Hybrid organic–inorganic structures trigger the formation of primitive cell-like compartments. Proceedings of the National Academy of Sciences 2023, 120 (33) https://doi.org/10.1073/pnas.2300491120
    6. K. A. Pavlov, N. A. Kovalenko, L. A. Azarova, E. A. Kravtsov, T. V. Kulevoy, S. V. Grigoryev. Small-Angle Neutron Scattering Instrument for the DARIA Compact Neutron Source. Journal of Surface Investigation: X-ray, Synchrotron and Neutron Techniques 2023, 17 (4) , 810-817. https://doi.org/10.1134/S1027451023040134
    7. K. A. Pavlov, N. A. Kovalenko, L. A. Azarova, E. A. Kravtsov, T. V. Kulevoy, S. V. Grigoriev. Small-Angle Neutron Scattering Instrument for Compact Neutron Source DARIA. Поверхность. Рентгеновские, синхротронные и нейтронные исследования 2023, (7) , 84-92. https://doi.org/10.31857/S1028096023070130
    8. Loreto Misuraca, Roland Winter, Bruno Demé, Philippe M. Oger, Judith Peters. Molecular Rearrangements in Protomembrane Models Probed by Laurdan Fluorescence. Membranes 2023, 13 (4) , 386. https://doi.org/10.3390/membranes13040386
    9. Loreto Misuraca, Josephine LoRicco, Philippe Oger, Judith Peters, Bruno Demé. Incorporation and localisation of alkanes in a protomembrane model by neutron diffraction. Biochimica et Biophysica Acta (BBA) - Biomembranes 2023, 1865 (3) , 184119. https://doi.org/10.1016/j.bbamem.2023.184119
    10. Susovan Sarkar, Shikha Dagar, Kushan Lahiri, Sudha Rajamani. pH‐Responsive Self‐Assembled Compartments as Tuneable Model Protocellular Membrane Systems**. ChemBioChem 2022, 23 (24) https://doi.org/10.1002/cbic.202200371
    11. Loreto Misuraca, Tatsuhito Matsuo, Aline Cisse, Josephine LoRicco, Antonio Caliò, Jean-Marc Zanotti, Bruno Demé, Philippe Oger, Judith Peters. High temperature molecular motions within a model protomembrane architecture. Physical Chemistry Chemical Physics 2022, 24 (24) , 15083-15090. https://doi.org/10.1039/D2CP01205G
    12. Loreto Misuraca, Antonino Caliò, Josephine G. LoRicco, Ingo Hoffmann, Roland Winter, Bruno Demé, Judith Peters, Philippe M. Oger. Alkanes as Membrane Regulators of the Response of Early Membranes to Extreme Temperatures. Life 2022, 12 (3) , 445. https://doi.org/10.3390/life12030445
    13. Judith Peters. High Hydrostatic Pressure–A Key Element to Investigate Molecular Dynamics in Biosystems. Frontiers in Physics 2022, 9 https://doi.org/10.3389/fphy.2021.801539
    14. Marta Salvador-Castell, Maksym Golub, Nelli Erwin, Bruno Demé, Nicholas J. Brooks, Roland Winter, Judith Peters, Philippe M. Oger. Characterisation of a synthetic Archeal membrane reveals a possible new adaptation route to extreme conditions. Communications Biology 2021, 4 (1) https://doi.org/10.1038/s42003-021-02178-y
    15. Loreto Misuraca, Bruno Demé, Philippe Oger, Judith Peters. Alkanes increase the stability of early life membrane models under extreme pressure and temperature conditions. Communications Chemistry 2021, 4 (1) https://doi.org/10.1038/s42004-021-00467-5
    16. Nicolas Martin, Jean‐Paul Douliez. Fatty Acid Vesicles and Coacervates as Model Prebiotic Protocells. ChemSystemsChem 2021, 3 (6) https://doi.org/10.1002/syst.202100024
    Download PDF
    Go to Langmuir
    Get e-Alerts
    Get e-Alerts

    Langmuir

    Cite this: Langmuir 2020, 36, 45, 13516–13526
    Click to copy citationCitation copied!
    https://doi.org/10.1021/acs.langmuir.0c02258
    Published November 4, 2020
    Copyright © 2020 American Chemical Society
    Request reuse permissions

    Article Views

    696

    Altmetric

    -

    Citations

    16
    Learn about these metrics

    Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.

    Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.

    The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.