Nickel-Catalyzed Deoxycyanation of Activated Phenols via Cyanurate Intermediates with Zn(CN)2: A Route to Aryl NitrilesClick to copy article linkArticle link copied!
- Majid M. Heravi*Majid M. Heravi*E-mail: [email protected]Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, IranMore by Majid M. Heravi
- Farhad Panahi*Farhad Panahi*E-mail: [email protected]Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran, IranChemistry Department, College of Sciences, Shiraz University, Shiraz 71454, IranMore by Farhad Panahi
- Nasser IranpoorNasser IranpoorChemistry Department, College of Sciences, Shiraz University, Shiraz 71454, IranMore by Nasser Iranpoor
Abstract

A novel, and efficient nickel-catalyzed deoxycyanation of phenolic compounds using relatively nontoxic Zn(CN)2 as the cyanide source was developed. The reaction of C–O bond activated phenolic compounds by 2,4,6-trichloro-1,3,5-triazine with Zn(CN)2 in the presence of a nickel precatalyst afforded the aromatic nitriles in good to excellent yields.
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