CNC-Milled Superhydrophobic Macroporous Monoliths for 3D Cell CultureClick to copy article linkArticle link copied!
- Gen Hayase*Gen Hayase*Email: [email protected] (G.H.).International Center for Materials Nanoarchitectonics, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, JapanMore by Gen Hayase
- Daisuke Yoshino*Daisuke Yoshino*Email: [email protected] (D.Y.).Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo 184-8588, JapanMore by Daisuke Yoshino
Abstract
High-strength macroporous monoliths can be obtained by the simple mixing of boehmite nanofiber aqueous acetate dispersions with methyltrimethoxysilane. On the boehmite nanofiber–polymethylsilsesquioxane monoliths, we can fabricate structures smaller than a millimeter in size by computer numerical control (CNC) milling, resulting in a machined surface that is superhydrophobic and biocompatible. Using this strategy, we fabricated a superhydrophobic multiwell plate that holds water droplets to produce 3D cell culture environments for various cell types. We expect these superhydrophobic monoliths to have future applications in 3D tissue construction.
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This article is cited by 11 publications.
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