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Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications
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    Polycrystalline Diamond Coating of Additively Manufactured Titanium for Biomedical Applications
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    ACS Applied Materials & Interfaces

    Cite this: ACS Appl. Mater. Interfaces 2018, 10, 10, 8474–8484
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    https://doi.org/10.1021/acsami.7b18596
    Published February 22, 2018
    Copyright © 2018 American Chemical Society

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    Additive manufacturing using selective laser melted titanium (SLM-Ti) is used to create bespoke items across many diverse fields such as medicine, defense, and aerospace. Despite great progress in orthopedic implant applications, such as for “just in time” implants, significant challenges remain with regards to material osseointegration and the susceptibility to bacterial colonization on the implant. Here, we show that polycrystalline diamond coatings on these titanium samples can enhance biological scaffold interaction improving medical implant applicability. The highly conformable coating exhibited excellent bonding to the substrate. Relative to uncoated SLM-Ti, the diamond coated samples showed enhanced mammalian cell growth, enriched apatite deposition, and reduced microbial S. aureus activity. These results open new opportunities for novel coatings on SLM-Ti devices in general and especially show promise for improved biomedical implants.

    Copyright © 2018 American Chemical Society

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    • Discussion about scaling from planar to nonplanar scaffolds in addition to the wettability and bacterial attachment, material synthesis during CVD growth, chemical composition of PCD, surface morphology of SLM-Ti and PCD, contact angles on different surface morphologies, bacterial density between SLM-Ti and PCD (PDF)

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    This article is cited by 65 publications.

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    2. Aaqil Rifai, Nhiem Tran, Victoria Leitch, Marsilea A. Booth, Richard Williams, Kate Fox. Osteoblast Cell Response on Polycrystalline Diamond-Coated Additively Manufactured Scaffolds. ACS Applied Bio Materials 2021, 4 (10) , 7509-7516. https://doi.org/10.1021/acsabm.1c00757
    3. Tao Wang, Lei Huang, Yuzhi Liu, Xingxing Li, Chunhua Liu, Stephan Handschuh-Wang, Yang Xu, Ying Zhao, Yongbing Tang. Robust Biomimetic Hierarchical Diamond Architecture with a Self-Cleaning, Antibacterial, and Antibiofouling Surface. ACS Applied Materials & Interfaces 2020, 12 (21) , 24432-24441. https://doi.org/10.1021/acsami.0c02460
    4. Aaron Elbourne, Samuel Cheeseman, Paul Atkin, Nghia P. Truong, Nitu Syed, Ali Zavabeti, Md Mohiuddin, Dorna Esrafilzadeh, Daniel Cozzolino, Chris F. McConville, Michael D. Dickey, Russell J. Crawford, Kourosh Kalantar-Zadeh, James Chapman, Torben Daeneke, Vi Khanh Truong. Antibacterial Liquid Metals: Biofilm Treatment via Magnetic Activation. ACS Nano 2020, 14 (1) , 802-817. https://doi.org/10.1021/acsnano.9b07861
    5. Kate Fox, Nour Mani, Aaqil Rifai, Philipp Reineck, Alan Jones, Phong A. Tran, Ali Ramezannejad, Milan Brandt, Brant C. Gibson, Andrew D. Greentree, Nhiem Tran. 3D-Printed Diamond–Titanium Composite: A Hybrid Material for Implant Engineering. ACS Applied Bio Materials 2020, 3 (1) , 29-36. https://doi.org/10.1021/acsabm.9b00801
    6. Piumie Rajapaksha, Samuel Cheeseman, Stuart Hombsch, Billy James Murdoch, Sheeana Gangadoo, Ewan W. Blanch, Yen Truong, Daniel Cozzolino, Chris F. McConville, Russell J. Crawford, Vi Khanh Truong, Aaron Elbourne, James Chapman. Antibacterial Properties of Graphene Oxide–Copper Oxide Nanoparticle Nanocomposites. ACS Applied Bio Materials 2019, 2 (12) , 5687-5696. https://doi.org/10.1021/acsabm.9b00754
    7. Aaqil Rifai, Nhiem Tran, Philipp Reineck, Aaron Elbourne, Edwin Mayes, Avik Sarker, Chaitali Dekiwadia, Elena P. Ivanova, Russell J. Crawford, Takeshi Ohshima, Brant C. Gibson, Andrew D. Greentree, Elena Pirogova, Kate Fox. Engineering the Interface: Nanodiamond Coating on 3D-Printed Titanium Promotes Mammalian Cell Growth and Inhibits Staphylococcus aureus Colonization. ACS Applied Materials & Interfaces 2019, 11 (27) , 24588-24597. https://doi.org/10.1021/acsami.9b07064
    8. Nazrah Maher, Anum Mahmood, Muhammad Amber Fareed, Naresh Kumar, Dinesh Rokaya, Muhammad Sohail Zafar. An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications. Journal of Advanced Research 2025, 72 , 265-286. https://doi.org/10.1016/j.jare.2024.07.016
    9. Amparo Vanaclocha, Vicente Vanaclocha, Carlos M. Atienza, Pablo Jordá-Gómez, Víctor Primo-Capella, Jose R. Blasco, Luis Portolés, Nieves Saiz-Sapena, Leyre Vanaclocha. Effect of Ti6Al4V Alloy Surface and Porosity on Bone Osseointegration: In Vivo Pilot Study in Rabbits. Materials 2025, 18 (9) , 2141. https://doi.org/10.3390/ma18092141
    10. Ying Wen, Yingyu Ding, Luqi Chang, Xiejing Luo, Bingxuan Qiao, Chaofang Dong, Sefei Yang. Effect of designed pore size on properties of additively manufactured TC4 with micro-nano biomedical surface. Journal of Materials Research and Technology 2025, 36 , 5320-5331. https://doi.org/10.1016/j.jmrt.2025.04.047
    11. Ana Maria Gianina Rehner (Costache), Elena-Theodora Moldoveanu, Adelina-Gabriela Niculescu, Florentina Cornelia Bîclesanu, Anna Maria Pangică, Alexandru Mihai Grumezescu, George-Alexandru Croitoru. Advances in Dental Implants: A Review of In Vitro and In Vivo Testing with Nanoparticle Coatings. Journal of Composites Science 2025, 9 (3) , 140. https://doi.org/10.3390/jcs9030140
    12. Jin Zhang, Hengwei Yan, Zhanwei Liu, Yonghui Yang, Guang Yang. Study on a new molten salt for electrolytic preparation of Ti: dissolution mechanism and kinetic analysis of TiO2 in NaCl-KCl-K2TiF6. Journal of Alloys and Compounds 2024, 1005 , 176125. https://doi.org/10.1016/j.jallcom.2024.176125
    13. Jian Qin, Peiyao Jing, Hongtao Zhu, Xinyi Song, Xu Su, Weimin Long, Zidong Wang. Recent progress in the fabrication of diamond joints/coatings/composites via laser technology. Welding in the World 2024, 68 (9) , 2391-2422. https://doi.org/10.1007/s40194-023-01655-8
    14. Ningkang Zhao, Meiqi Song, Xifang Zhang, Wei Xu, Xiaojing Liu. Nanodiamond Coating in Energy and Engineering Fields: Synthesis Methods, Characteristics, and Applications. Small 2024, 5 https://doi.org/10.1002/smll.202401292
    15. Mehran Ghasemlou, Navya PN, Katia Alexander, Ali Zavabeti, Peter C. Sherrell, Elena P. Ivanova, Benu Adhikari, Minoo Naebe, Suresh K. Bhargava. Fluorescent Nanocarbons: From Synthesis and Structure to Cancer Imaging and Therapy. Advanced Materials 2024, 36 (19) https://doi.org/10.1002/adma.202312474
    16. Guang Yang, Hengwei Yan, Zhanwei Liu, Wenhui Ma, Shenghui Guo, Yonghui Yang. Preparation of titanium powder using a combined method of aluminothermic reduction and molten salt electrolysis. Solid State Sciences 2024, 148 , 107328. https://doi.org/10.1016/j.solidstatesciences.2023.107328
    17. Roxanne Hubesch, Uzma Malik, PR. Selvakannan, Lakshmi Kantam Mannepalli, Suresh K. Bhargava. Oberflächenmodifikation von additiv hergestellten Materialien: Hinzufügen von Funktionalität als vierte Dimension. 2024, 155-189. https://doi.org/10.1007/978-981-97-0978-6_6
    18. Rocco Carcione, Valeria Guglielmotti, Francesco Mura, Silvia Orlanducci, Emanuela Tamburri. Monitoring of Carbonated Hydroxyapatite Growth on Modified Polycrystalline CVD-Diamond Coatings on Titanium Substrates. Crystals 2024, 14 (1) , 66. https://doi.org/10.3390/cryst14010066
    19. Weijun Liu, Wanqiu Li, Huiru Wang, Hongyou Bian, Kai Zhang. Surface Modification of Porous Titanium and Titanium Alloy Implants Manufactured by Selective Laser Melting: A Review. Advanced Engineering Materials 2023, 25 (21) https://doi.org/10.1002/adem.202300765
    20. Zhaojie Chen, Jin Xie, Xicong Zhu. Experimental study on surface physical behaviour and integrity of polycrystalline diamond (PCD) in micron-scale abrasive flow assisted impulse-discharge machining. International Journal of Refractory Metals and Hard Materials 2023, 116 , 106330. https://doi.org/10.1016/j.ijrmhm.2023.106330
    21. Awadesh Kumar Mallik, Fernando Lloret, Marina Gutierrez, Rozita Rouzbahani, Paulius Pobedinskas, Wen-Ching Shih, Ken Haenen. Deposition and Characterisation of a Diamond/Ti/Diamond Multilayer Structure. Coatings 2023, 13 (11) , 1914. https://doi.org/10.3390/coatings13111914
    22. Shuai Long, Jiang Zhu, Yiwan Jing, Si He, Lijia Cheng, Zheng Shi. A Comprehensive Review of Surface Modification Techniques for Enhancing the Biocompatibility of 3D-Printed Titanium Implants. Coatings 2023, 13 (11) , 1917. https://doi.org/10.3390/coatings13111917
    23. Karlis Grundsteins, Kateryna Diedkova, Viktoriia Korniienko, Anita Stoppel, Sascha Balakin, Kaspars Jekabsons, Una Riekstina, Natalia Waloszczyk, Agata Kołkowska, Yuliia Varava, Jörg Opitz, Wojciech Simka, Natalia Beshchasna, Maksym Pogorielov. Nanodiamond Decorated PEO Oxide Coatings on NiTi Alloy. Nanomaterials 2023, 13 (18) , 2601. https://doi.org/10.3390/nano13182601
    24. Changhui Song, Lisha Liu, Zhengtai Deng, Haoyang Lei, Fuzhen Yuan, Yongqiang Yang, Yueyue Li, Jiakuo Yu. Research progress on the design and performance of porous titanium alloy bone implants. Journal of Materials Research and Technology 2023, 23 , 2626-2641. https://doi.org/10.1016/j.jmrt.2023.01.155
    25. Alireza Nouri, Anahita Rohani Shirvan, Yuncang Li, Cuie Wen. Surface modification of additively manufactured metallic biomaterials with active antipathogenic properties. Smart Materials in Manufacturing 2023, 1 , 100001. https://doi.org/10.1016/j.smmf.2022.100001
    26. Maria Letizia Terranova. Key Challenges in Diamond Coating of Titanium Implants: Current Status and Future Prospects. Biomedicines 2022, 10 (12) , 3149. https://doi.org/10.3390/biomedicines10123149
    27. S. X. Liang, K. Y. Liu, L. X. Yin, G. W. Huang, Y. D. Shi, L. Y. Zheng, Z. G. Xing. Review of major technologies improving surface performances of Ti alloys for implant biomaterials. Journal of Vacuum Science & Technology A 2022, 40 (3) https://doi.org/10.1116/6.0001801
    28. Xiao Sheng, Ao Wang, Zhonghan Wang, He Liu, Jincheng Wang, Chen Li. Advanced Surface Modification for 3D-Printed Titanium Alloy Implant Interface Functionalization. Frontiers in Bioengineering and Biotechnology 2022, 10 https://doi.org/10.3389/fbioe.2022.850110
    29. Jingyuan Xu, Jiawen Zhang, Yangfan Shi, Jincheng Tang, Danni Huang, Ming Yan, Matthew S. Dargusch. Surface Modification of Biomedical Ti and Ti Alloys: A Review on Current Advances. Materials 2022, 15 (5) , 1749. https://doi.org/10.3390/ma15051749
    30. Ady Suwardi, FuKe Wang, Kun Xue, Ming‐Yong Han, Peili Teo, Pei Wang, Shijie Wang, Ye Liu, Enyi Ye, Zibiao Li, Xian Jun Loh. Machine Learning‐Driven Biomaterials Evolution. Advanced Materials 2022, 34 (1) https://doi.org/10.1002/adma.202102703
    31. Roxanne Hubesch, Uzma Malik, PR. Selvakannan, Lakshmi Kantam Mannepalli, Suresh K. Bhargava. Surface Modification of Additively Manufactured Materials: Adding Functionality as Fourth Dimension. 2022, 137-168. https://doi.org/10.1007/978-981-19-2293-0_6
    32. Ye Yuan, Wulin Yang, Jianquan Sang, Jiajun Zhu, Licai Fu, Deyi Li, Lingping Zhou. Periodic nano ripple fabricated on diamond and its structure damage repair. Diamond and Related Materials 2021, 120 , 108670. https://doi.org/10.1016/j.diamond.2021.108670
    33. Muhammad Bilal, Hairong Cheng, Reyna Berenice González-González, Roberto Parra-Saldívar, Hafiz M.N. Iqbal. Bio-applications and biotechnological applications of nanodiamonds. Journal of Materials Research and Technology 2021, 15 , 6175-6189. https://doi.org/10.1016/j.jmrt.2021.11.037
    34. Marsilea A. Booth, Leon Pope, Peter C. Sherrell, Alastair Stacey, Phong A. Tran, Kate E. Fox. Polycrystalline diamond coating on 3D printed titanium scaffolds: Surface characterisation and foreign body response. Materials Science and Engineering: C 2021, 130 , 112467. https://doi.org/10.1016/j.msec.2021.112467
    35. Guang Zhu, Guocheng Wang, Jiao Jiao Li. Advances in implant surface modifications to improve osseointegration. Materials Advances 2021, 2 (21) , 6901-6927. https://doi.org/10.1039/D1MA00675D
    36. Daniel Merker, Yordan Handzhiyski, Rolf Merz, Michael Kopnarski, Johann Peter Reithmaier, Cyril Popov, Margarita D. Apostolova. Influence of surface termination of ultrananocrystalline diamond films coated on titanium on response of human osteoblast cells: A proteome study. Materials Science and Engineering: C 2021, 128 , 112289. https://doi.org/10.1016/j.msec.2021.112289
    37. Jessica S. L. Fong, Marsilea A. Booth, Aaqil Rifai, Kate Fox, Amy Gelmi. Diamond in the Rough: Toward Improved Materials for the Bone−Implant Interface. Advanced Healthcare Materials 2021, 10 (14) https://doi.org/10.1002/adhm.202100007
    38. Stephan Handschuh‐Wang, Tao Wang, Yongbing Tang. Ultrathin Diamond Nanofilms—Development, Challenges, and Applications. Small 2021, 17 (30) https://doi.org/10.1002/smll.202007529
    39. Xingyong Wang, Stephan Handschuh‐Wang, Yang Xu, Li Xiang, Zhiye Zhou, Tao Wang, Yongbing Tang. Hierarchical Micro/Nanostructured Diamond Gradient Surface for Controlled Water Transport and Fog Collection. Advanced Materials Interfaces 2021, 8 (12) https://doi.org/10.1002/admi.202100196
    40. Prem C Pandey, Shubhangi Shukla, Govind Pandey, Roger J Narayan. Nanostructured diamond for biomedical applications. Nanotechnology 2021, 32 (13) , 132001. https://doi.org/10.1088/1361-6528/abd2e7
    41. Aaqil Rifai, Shadi Houshyar, Kate Fox. Progress towards 3D-printing diamond for medical implants: A review. Annals of 3D Printed Medicine 2021, 1 , 100002. https://doi.org/10.1016/j.stlm.2020.100002
    42. Rocco Carcione, Sara Politi, Erica Iacob, Cristina Potrich, Lorenzo Lunelli, Lia Emauela Vanzetti, Ruben Bartali, Victor Micheli, Giancarlo Pepponi, Maria Letizia Terranova, Emanuela Tamburri. Exploring a new approach for regenerative medicine: Ti-doped polycrystalline diamond layers as bioactive platforms for osteoblast-like cells growth. Applied Surface Science 2021, 540 , 148334. https://doi.org/10.1016/j.apsusc.2020.148334
    43. Aaqil Rifai, Daniel Creedon, Nhiem Tran, Maryam Hejazi, David Garrett, Andrew D. Greentree, Elena Pirogova, Alastair Stacey, Kate Fox. Highly uniform polycrystalline diamond coatings of three-dimensional structures. Surface and Coatings Technology 2021, 408 , 126815. https://doi.org/10.1016/j.surfcoat.2020.126815
    44. Moon Sung Kang, Jong Ho Lee, Suck Won Hong, Jong Hun Lee, Dong-Wook Han. Nanocomposites for Enhanced Osseointegration of Dental and Orthopedic Implants Revisited: Surface Functionalization by Carbon Nanomaterial Coatings. Journal of Composites Science 2021, 5 (1) , 23. https://doi.org/10.3390/jcs5010023
    45. Nour Mani, Aaqil Rifai, Shadi Houshyar, Marsilea A. Booth, Kate Fox. Diamond in medical devices and sensors: An overview of diamond surfaces. MEDICAL DEVICES & SENSORS 2020, 3 (6) https://doi.org/10.1002/mds3.10127
    46. Monika Kosowska, Paulina Listewnik, Daria Majchrowicz, Michał Rycewicz, Mikhael Bechelany, Yafit Fleger, Mingzhou Chen, Dror Fixler, Kishan Dholakia, Małgorzata Szczerska. Microscale diamond protection for a ZnO coated fiber optic sensor. Scientific Reports 2020, 10 (1) https://doi.org/10.1038/s41598-020-76253-5
    47. Bing Yang, Haining Li, Biao Yu, Nan Huang, Lusheng Liu, Xin Jiang. Deposition of highly adhesive nanocrystalline diamond films on Ti substrates via diamond/SiC composite interlayers. Diamond and Related Materials 2020, 108 , 107928. https://doi.org/10.1016/j.diamond.2020.107928
    48. Paulina Kazimierczak, Agata Przekora. Osteoconductive and Osteoinductive Surface Modifications of Biomaterials for Bone Regeneration: A Concise Review. Coatings 2020, 10 (10) , 971. https://doi.org/10.3390/coatings10100971
    49. Avik Sarker, Martin Leary, Kate Fox. Metallic additive manufacturing for bone-interfacing implants. Biointerphases 2020, 15 (5) https://doi.org/10.1116/6.0000414
    50. Neda Norouzi, Yori Ong, Viraj G. Damle, Mohammad B. Habibi Najafi, Romana Schirhagl. Effect of medium and aggregation on antibacterial activity of nanodiamonds. Materials Science and Engineering: C 2020, 112 , 110930. https://doi.org/10.1016/j.msec.2020.110930
    51. Guang Zeng, Saden H. Zahiri, Stefan Gulizia, Yaping Chen, Chenglong Xu, Xiao-Bo Chen, Ivan Cole. A comparative study of cell growth on a cold sprayed Ti–Ta composite. Journal of Alloys and Compounds 2020, 826 , 154014. https://doi.org/10.1016/j.jallcom.2020.154014
    52. Pengzi Xu, Xiaoqin Zhou, Qiang Liu. Tribochemical machining of polycrystalline diamond using ferrous tool materials. Machining Science and Technology 2020, 24 (1) , 1-25. https://doi.org/10.1080/10910344.2019.1636262
    53. Phong A. Tran, Avik Sarker, Nhiem Tran, Christopher Jeffery, Aaqil Rifai, Kate Fox. Coatings on metallic implants for biomedical applications. 2020, 359-385. https://doi.org/10.1016/B978-0-08-102965-7.00011-4
    54. Maria P. Nikolova, Murthy S. Chavali. Recent advances in biomaterials for 3D scaffolds: A review. Bioactive Materials 2019, 4 , 271-292. https://doi.org/10.1016/j.bioactmat.2019.10.005
    55. Rocco Carcione, Emanuela Tamburri, Ruben Bartali, Giorgio Speranza, Victor Micheli, Giancarlo Pepponi, Pierluigi Bellutti, Maria Letizia Terranova. On the route to produce conductive Ni-related color centers in CVD-grown diamond. Multifunctional Materials 2019, 2 (3) , 035001. https://doi.org/10.1088/2399-7532/ab2c35
    56. Long Bai, Cheng Gong, Xiaohong Chen, Yuanxi Sun, Junfang Zhang, Lecai Cai, Shengyan Zhu, Sheng Quan Xie. Additive Manufacturing of Customized Metallic Orthopedic Implants: Materials, Structures, and Surface Modifications. Metals 2019, 9 (9) , 1004. https://doi.org/10.3390/met9091004
    57. Shadi Houshyar, G. Sathish Kumar, Aaqil Rifai, Nhiem Tran, Rajkishore Nayak, Robert A. Shanks, Rajiv Padhye, Kate Fox, Amitava Bhattacharyya. Nanodiamond/poly-ε-caprolactone nanofibrous scaffold for wound management. Materials Science and Engineering: C 2019, 100 , 378-387. https://doi.org/10.1016/j.msec.2019.02.110
    58. Aaron Elbourne, James Chapman, Amy Gelmi, Daniel Cozzolino, Russell J. Crawford, Vi Khanh Truong. Bacterial-nanostructure interactions: The role of cell elasticity and adhesion forces. Journal of Colloid and Interface Science 2019, 546 , 192-210. https://doi.org/10.1016/j.jcis.2019.03.050
    59. Xinran Zhang, Haotian Li, Jiaqiang Liu, Hui Wang, Wenjun Sun, Kaili Lin, Xudong Wang, Steve Guofang Shen. Amorphous carbon modification on implant surface: a general strategy to enhance osteogenic differentiation for diverse biomaterials via FAK/ERK1/2 signaling pathways. Journal of Materials Chemistry B 2019, 7 (15) , 2518-2533. https://doi.org/10.1039/C8TB02850H
    60. Sandeep Kumar, Monika Nehra, Deepak Kedia, Neeraj Dilbaghi, K. Tankeshwar, Ki-Hyun Kim. Nanodiamonds: Emerging face of future nanotechnology. Carbon 2019, 143 , 678-699. https://doi.org/10.1016/j.carbon.2018.11.060
    61. Avik Sarker, Nhiem Tran, Aaqil Rifai, Milan Brandt, Phong A Tran, Martin Leary, Kate Fox, Richard Williams. Rational design of additively manufactured Ti6Al4V implants to control Staphylococcus aureus biofilm formation. Materialia 2019, 5 , 100250. https://doi.org/10.1016/j.mtla.2019.100250
    62. H.-T. (Peter) Liu. Advanced Waterjet Technology for Machining Curved and Layered Structures. Curved and Layered Structures 2019, 6 (1) , 41-56. https://doi.org/10.1515/cls-2019-0004
    63. Swastik Pradhan, Kalipada Maity, Sunpreet Singh, Chander Prakash. Micro-machining Performance Assessment of Ti-Based Biomedical Alloy: A Finite Element Case Study. 2019, 157-183. https://doi.org/10.1007/978-3-030-13951-3_8
    64. S. Y. Ong, R. J. J. van Harmelen, N. Norouzi, F. Offens, I. M. Venema, M. B. Habibi Najafi, R. Schirhagl. Interaction of nanodiamonds with bacteria. Nanoscale 2018, 10 (36) , 17117-17124. https://doi.org/10.1039/C8NR05183F
    65. Jiangying Ru, Qiang Wei, Lianqing Yang, Jing Qin, Liangchen Tang, Jie Wei, Lieping Guo, Yunfei Niu. Zein regulating apatite mineralization, degradability, in vitro cells responses and in vivo osteogenesis of 3D-printed scaffold of n-MS/ZN/PCL ternary composite. RSC Advances 2018, 8 (34) , 18745-18756. https://doi.org/10.1039/C8RA02595A

    ACS Applied Materials & Interfaces

    Cite this: ACS Appl. Mater. Interfaces 2018, 10, 10, 8474–8484
    Click to copy citationCitation copied!
    https://doi.org/10.1021/acsami.7b18596
    Published February 22, 2018
    Copyright © 2018 American Chemical Society

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