LCST-Type Phase Separation of Poly[poly(ethylene glycol) methyl ether methacrylate]s in Hydrofluorocarbon
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Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan
*(T.T.) E-mail: [email protected]
*(M.S.) E-mail: [email protected]
Abstract
Poly[poly(ethylene glycol) methyl ether methacrylate]s [poly(PEGMA)s] sharply and reversibly exhibited lower critical solution temperature (LCST)-type phase separation in 2H,3H-perfluoropentane (2HPFP). The cloud points decreased from 52 to 41 °C with increasing the PEG pendant length [−(CH2CH2O)mCH3: m = 4.5, 9, 19]. The cloud point was precisely controlled via the addition of perfluoroalkanes (e.g., perfluorooctane) to the 2HPFP solution: typically, it was inversely proportional to the amount of perfluorooctane in the mixture. The unique thermoresponsive solubility further afforded the temperature-mediated micellization of a block copolymer of PEG19MA and methyl methacrylate (MMA) in 2HPFP to uniquely give a PEG-core micelle with PMMA shell. Therefore, the LCST phase separation properties in the hydrofluorocarbon would open new vistas for thermoresponsive polymeric materials.
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