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2023 Rising Stars in Measurement Science

Cite this: ACS Meas. Sci. Au 2024, 4, 2, 144–152
Publication Date (Web):March 19, 2024
https://doi.org/10.1021/acsmeasuresciau.4c00013

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It is with great excitement that we celebrate our first group of Rising Stars in Measurement Science here at ACS Measurement Science Au. With over 300 nominations, it was very challenging to choose the first group of Rising Stars in Measurement Science. However, I’m pleased with this group of 20 Rising Stars featured in this virtual special issue showing the diversity in the field of measurement science and the new directions that the field is going in. Although the applications of measurement science are diverse ranging from single entity detection to biosensing to environmental monitoring, and this group encompasses the best of separations, electrochemistry, spectroscopy, and mass spectrometry, the emerging themes of machine learning/artificial intelligence, portable assays and sensors, and next generation -omics approaches show the future of this field. To all of the Rising Stars, a big congratulations on your impressive accomplishments and great research (Figure 1). To our young readers, we hope these rising stars are encouraging role models to you in starting a career in the field of measurement science!

Figure 1

Figure 1. 2023 Rising Stars in Measurement Science.

Using nanophotonics as a Swiss knife, Eden’s ingenuity is advancing measurement science through simple, yet powerful, (bio)analytical platforms.

Eden Morales-Narváez is currently the Head of the Biophotonic Nanosensors Laboratory at the Center for Applied Physics and Advanced Technology of the National Autonomous University of Mexico (Universidad Nacional Autónoma de México, UNAM). His research is focused on the development and application of novel (bio)sensing platforms, particularly using nanophotonic phenomena. In general, he is interested in green technologies, smart materials, integrated biosensors, wearable devices, flexible photonics, and healthcare 4.0/5.0. He received a degree in bionics engineering from the National Polytechnic Institute of Mexico in 2006 and his Ph.D. in biomedical engineering from the Polytechnic University of Catalonia, Spain in 2013. He was a Postdoctoral Researcher at Catalan Institute of Nanoscience and Nanotechnology in the group lead by Prof. Arben Merkoçi and started his independent career in late 2016 at the Center for Research in Optics (Mexico). He is a member of several editorial boards including Analytical Chemistry, Biosensors & Bioelectronics X, Journal of Physics: Photonics and Green Analytical Chemistry, among others. He has also been recognized as an Emerging Leader 2020 by Journal of Physics: Photonics. For more information about Dr. Morales-Narváez’s research group, please visit their web page: https://eden662.wixsite.com/nanobiophotonics.

Prof. Morales-Narváez’s Article in this issue is titled “Disposable Device for Bacterial Vaginosis Detection” (DOI: 10.1021/acsmeasuresciau.3c00007).

This in vitro luminescent assay for detecting G-protein-coupled receptor (GPCR) activity will find broad applications including GPCR agonist detection, screening, and in vitro GPCR characterization.

Wenjing Wang is a Research Assistant Professor in the Life Sciences Institute and William R. Roush Assistant Professor in the Department of Chemistry at the University of Michigan. She obtained B.S. in Chemistry in 2006 from Xiamen University, China, and Ph.D. in Bioorganic Chemistry in 2012 from Michigan State University under the mentorship of Prof. Babak Borhan. Following her doctoral study, she conducted postdoctoral training from 2012 to 2018 at the Massachusetts Institute of Technology and Stanford University under the mentorship of Prof. Alice Ting. Dr. Wang’s research laboratory focuses on utilizing directed evolution-based protein engineering methods to design a range of molecular sensors for mapping neuromodulators and recording neuronal activity in animal models. Additionally, her group develops new classes of optogenetic and chemogenetic tools to manipulate cellular signaling and neuronal activity with a temporal gating. Furthermore, her team is actively involved in developing protein-based biologics as research tools and potential therapeutics for targeting protein aggregates in neurodegenerative diseases. In this paper, Dr. Wang’s team describes a new in vitro luminescent assay for detecting G-protein-coupled receptor’s activity that can find numerous applications. For more information about Dr. Wang’s research group, please visit their web page: https://www.lsi.umich.edu/science/our-labs/wang-lab.

Dr. Wang’s Letter in this issue is titled "Accessible and Generalizable in Vitro Luminescence Assay for Detecting GPCR Activation" (DOI: 10.1021/acsmeasuresciau.3c00021).

My research has been focused on leveraging advanced sample isolation and microfluidic sample processing technologies for low-input proteomics analysis, including single cells and tissue sections.

Dr. Ying Zhu is a Senior Principal Scientist and Group Lead in the Department of Microchemistry, Proteomics, and Lipidomics at Genentech. He leads a team focusing on the development and implementation of single-cell and spatial proteomics technologies for early stage drug discovery. He coinvented the nanoPOTS platform, which is the key technology in enabling single-cell proteomics, spatial proteomics, and multiomics. Prior to joining Genentech, he was an Associate Professor at Zhejiang University and a Senior Research Scientist at Pacific Northwest National Laboratory. Dr. Zhu obtained his Ph.D. degree in Analytical Chemistry in 2010 from Zhejiang University with the guidance of Prof. Qun Fang. Next, He subsequently did two-way postdoctoral researches at the Engineering School of Zhejiang University under the mentorship of Prof. Ying Mu in 2013, and at Pacific Northwest National Laboratory under the mentorship of Dr. Ryan Kelly in 2018. Dr. Zhu’s research focuses at the interface of advanced optics, automation, microfluidics, and computational technologies for mass spectrometry-based bioanalysis. For more information about Dr. Zhu’s research group, please visit their web page: https://www.gene.com/scientists/our-scientists/ying-zhu.

Dr. Zhu’s Article in this issue is titled "Spatial Proteomics toward Subcellular Resolution by Coupling Deep Ultraviolet Laser Ablation with Nanodroplet Sample Preparation" (DOI: 10.1021/acsmeasuresciau.3c00033).

The research conducted by Peng group on protein-guided nontargeted analysis has introduced a novel strategy for the identification of toxicity-driving chemicals from environmental mixtures.

Hui Peng holds the position of Associate Professor in the Department of Chemistry at the University of Toronto. He obtained his B.Sc. in 2008 and Ph.D. in 2013 from Peking University in China. After completing postdoctoral fellowships at the University of Toronto (2013–2014) and the University of Saskatchewan (2014–2017), he started his independent research career at the University of Toronto in 2017. Over the past six years, Hui Peng has built a research program known as "environmental Chemical-Protein Interaction Network (eCPIN)", which was recently featured in Environmental Science. His group has developed innovative bioanalytical methods (e.g., APNA) to identify toxic chemical contaminants and protein targets on both the exposome- and proteome-wide scale. He has made several distinguished contributions to the field of environmental chemistry and toxicology, and received multiple awards, including the Connaught New Researcher Award as well as the Ontario Early Researcher Award. As an advisor, Hui Peng has mentored over 30 next-generation environmental chemists, including seven PDFs and nine graduate students. For more information about Dr. Peng’s research group, please visit their web page: https://sites.chem.utoronto.ca/penglab/.

Dr. Peng’s Article in this issue is titled "Screening of Indoor Transformation Products of Organophosphates and Organophosphites with an in Silico Spectral Database" (DOI: 10.1021/acsmeasuresciau.3c00039).

Clinic-friendly, nonbiopsy, cancer diagnosis technologies. Dr. Dey’s group works in designing nanoassembled gold sensors to detect biomarkers of cancer progression, using customized Raman technologies.

Priyanka Dey presently holds the position of Assistant Professor in Bioanalytical Chemistry at the University of Portsmouth in the United Kingdom. Her research ethos centers around translational diagnostics research. She is firmly committed to developing noninvasive clinical solutions for disease detection at stages that offer better treatment options and are less taxing on patients. Disease diagnosis is attempted either as body fluid tests and/or partial body scans. This is pursued by strategically combining (a) plasmonic nanostructures (particularly, gold nanoassemblies with controlled morphology and sub-10 nm interparticle distances) that help amplify Raman signals via surface enhanced Raman scattering (SERS) phenomenon and (b) modified Raman instrumentation. Her research is supported by grants from the prestigious Royal Society, Royal Society of Chemistry, Community for Analytical Measurement Science (CAMS-UK) fellowship, and the University of Portsmouth.

Dr. Dey earned her doctoral degree in chemistry from the Queensland University of Technology (QUT) in Brisbane, Australia, in 2014. Her dissertation, focused on plasmonic nanostructures and optical molecular spectroscopy, received an “Outstanding Thesis Award”. Since completing her Ph.D., during her tenure as a postdoctoral researcher from 2015 to 2021, she has collaborated on significant research projects including single-particle nanoplasmonics and photonics at Ludwig Maximilian University (LMU) in Munich, Germany (within the EU FP7 “UNION” project), the development of optical nanobiosensors for point-of-care clinical applications at the Catalan Institute of Nanoscience and Nanotechnology (ICN2) in Barcelona, Spain (under the Horizon “RAIS” project), and the exploration of Raman nanotheranostics at the University of Exeter, UK (within the EPSRC Programme “RaNT”). In addition to her research endeavors, Priyanka is a strong advocate for Women in STEMM. She actively promotes the dissemination of research findings to the public through various channels, including interviews on BBC TV and radio, participation in Soapbox Science, blogs and Pint of Science. For more information about Dr. Dey’s research group, please visit their web page: https://researchportal.port.ac.uk/en/persons/priyanka-dey.

Dr. Dey’s Article in this issue is titled "Aiming for Maximized and Reproducible Enhancements in the Obstacle Race of SERS" (DOI: 10.1021/acsmeasuresciau.3c00037).

By developing interfacing technology of the nanosensor, it can advance innovative and practical application of sensor materials in fields requiring extensive biochemical data analysis.

Sooyeon Cho is an Assistant Professor in School of Chemical Engineering Sungkyunkwan University (SKKU) from 2022. He received his B.S. (2013) and Ph.D. (2019) from the Department of Chemical and Biomolecular Engineering at Korea Advanced Institute of Science and Technology (KAIST) with thesis advisor Prof. Hee-Tae Jung. He worked as a postdoctoral associate in the Department of Chemical Engineering at Massachusetts Institute of Technology (MIT) from 2019 to 2022 with Prof. Michael S. Strano. Sooyeon’s team at SKKU aims to develop advanced biochemical sensor systems for smart diagnostics, therapeutics, and process analytics (PAT) based on label-free fluorescent nanosensor technology. The primary focus of the team includes molecular recognition design of the nanosensor, interfacing the nanosensor with high-throughput form factors, and AI-driven analysis of multivariate sensing data. For more information about Dr. Cho’s research group, please visit their web page: www.sycholab.com.

Dr. Cho’s Perspective in this issue is titled "Nanosensor Chemical Cytometry: Advances and Opportunities in Cellular Therapy and Precision Medicine" (DOI: 10.1021/acsmeasuresciau.3c00038).

Prof. Tzu-En Lin is a pioneer in flexible electronics, advancing sustainable healthcare solutions through scanning electrochemical probes and MXene-based sensor technology.

Tzu-En Lin is a PTOT junior chair professor known for her contributions to the field of flexible electronics, particularly in paper electronics and soft-probe scanning electrochemical microscopy (soft-probe SECM). She received her Ph.D. from École Polytechnique Fédérale de Lausanne (EPFL) in Switzerland in 2017, under the mentorship of Prof. Hubert Girault. Prior to that, she earned her B.S. degree from National Taiwan University (NTU) in 2010, laying the foundation for her impressive academic journey. Dr. Lin’s academic pursuits have taken her around the world, including a stint as a visiting scholar at Stanford University under the guidance of Prof. Gerald Fuller. Subsequently, she pursued postdoctoral research at EPFL (Prof. Girault), and later at NTU, under the guidance of Prof. Wei-Fang Su. One of Dr. Lin’s notable achievements is her groundbreaking work on “AI-Assisted Fusion of Scanning Electrochemical Microscopy Images Using Novel Soft Probe.″ This pioneering research successfully integrated SECM with AI technology, earning the prestigious distinction of being featured on the journal supplementary cover of ACS Measurement Science Au. Another significant contribution to her credit is her research on “Monitoring Melanoma by Scanning Electrochemical Microscopy," published in Angewandte Chemie International Edition. This work garnered substantial attention from various media outlets, including Swiss Radio & TV. In addition to her work in scanning probe technology, she has dedicated herself to advancing the field of paper electronics and microneedle development using “Mxenes”, a group of remarkable two-dimensional materials known for their exceptional conductivity and biocompatibility. Looking ahead, Dr. Lin remains committed to furthering her research in the development of novel MXene-based electronics and the application of sustainable chemistry in the realm of wearable healthcare devices. Her dedication and contributions in these domains continue to make her a notable figure in the world of academia and scientific innovation. For more information about Dr. Lin’s research group, please visit their web page: https://sites.google.com/nycu.edu.tw/tel/home?authuser=1.

Dr. Lin’s Article in this issue is titled "MXene Nanosheets-Decorated Paper as a Green Electronics Material for Biosensing" (DOI: 10.1021/acsmeasuresciau.3c00043).

We investigate the feasibility of cross-matrix-matched calibration using Bayesian Hierarchical Modeling to correct for matrix effects associated with interspecie plasma protein binding.

Emanuela Gionfriddo is an Associate Professor in the Department of Chemistry and Biochemistry of the University of Toledo (OH, USA). Her research program focuses on understanding the partitioning of environmental pollutants in heterogeneous phases, including biological specimens, by using advanced separation and mass spectrometry tools. She earned her B.Sc. and M.Sc in Chemistry at the University of Calabria in Italy, graduating summa cum laude, and obtained her Ph.D. at the same institution in Prof. Giovanni Sindona laboratory. She then joined Prof. Pawliszyn’s group at the University of Waterloo (Ontario, Canada) as a Post-Doctoral Fellow and manager of the Gas-Chromatography section of the Industrially Focused Analytical Research Laboratory (InFAReL). Dr. Gionfriddo has authored over 60 peer-reviewed contributions including a patent on PTFE-based SPME coatings. Dr. Gionfriddo is one of the founding members of the Dr. Nina McClelland Laboratory for Water Chemistry and Environmental Analysis at The University of Toledo, and she is appointed to the Ohio Attorney General Yost’s Environmental Council of Advisors. Dr. Gionfriddo was the LCGC Emerging Leader in Chromatography Award, the 2023 Eastern Analytical Symposium Young Investigator Award and 2022 ACS Analytical Division Satinder Ahuja Award for Young Investigators in Separation Science. She also serves as the Chair-Elect of the ACS Analytical Chemistry Subdivision on Chromatography and Separation Chemistry. Her research program is currently funded by the National Science Foundation through the 2022 CAREER Award and several industrial partnerships. For more information about Dr. Gionfriddo’s research group, please visit their web page: https://www.utgmaslab.com/.

Dr. Gionfriddo’s Article in this issue is titled "Enhancing Quantitative Analysis of Xenobiotics in Blood Plasma through Cross-Matrix Calibration and Bayesian Hierarchical Modeling" (DOI: 10.1021/acsmeasuresciau.3c00049).

Pushing the measurement limit to single molecules for a deeper understanding of chemistry.

Yi-Lun Ying studied chemistry and obtained her Ph.D. in Analytical Chemistry from East China University of Science and Technology (ECUST). After a doctoral exchange study in the University of Birmingham, Dr. Ying carried out her postdoctoral research on nanopore electrochemical biosensors at ECUST. Since 2016, she has started her independent work. In 2019, she was promoted to professor at Nanjing University. Prof. Ying’s team currently focuses on nanopore electrochemistry for single-molecule analysis and single-molecule reaction, and developing intelligent nanopore instrumentations for single polymer sequencing and data storage. She has been recognized by several awards and honors, including the L’Oreal-UNESCO International Rising Talents, RSC Analyst Emerging Investigator Lectureship, and Young Chemists Awards of Chinese Chemical Society. She serves as an Editor for Results in Chemistry, Editorial Board Member for ACS Measurement Science Au and ChemElectroChem, and Advisory Board Member for Analyst. For more information about Dr. Ying’s research group, please visit their web page: https://chem.nju.edu.cn/yyl_en/list.htm.

Dr. Ying’s Article in this issue is titled "Electrochemical Visualization of Single-Molecule Thiol Substitution with Nanopore Measurement" (DOI: 10.1021/acsmeasuresciau.3c00046).

The main focus of our research is the use of luminescence based techniques for developing innovative/highly effective detection platforms for biomarkers of various diseases.

Dr. Muhammad Saqib is an Assistant Professor of Analytical Chemistry at Khwaja Fareed University of Engineering & Information Technology (KFUEIT) Pakistan. He received his M.Sc. (Analytical Chemistry) and M.Phil. (Analytical/Inorganic Chemistry) from University of Gujrat and University of Sargodha, respectively. He received his Ph.D. in Analytical Chemistry from University of Chinese Academy of Sciences in 2017 under the supervision of Prof. Guobao Xu. Prior to this position, he was a CAS President’s International Fellowship Initiative (PIFI) Postdoctoral Fellow with Prof. Yongdong Jin at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences (2018–2020), and a Postdoctoral Fellow with Prof. Rui Hao at Southern University of Science and Technology (2020–2022). His current research interests mainly focus on development and applications of chemiluminescence and electrochemiluminescence in global concerns about health, environment, and food safety. For more information about Dr. Saqib’s research group, please visit their web page: https://kfueit.edu.pk/faculty_profile/217.

Dr. Saqib’s Perspective in this issue is titled "Nanoscale Luminescence Imaging/Detection of Single Particles: State-of-the-Art and Future Prospects" (DOI: 10.1021/acsmeasuresciau.3c00052).

Aptamer (DNA-based bioreceptor)-modified nanopipette biosensors have the potential to monitor diverse small-molecule targets in complex systems such as biofluids and tissue with nanoscale spatial resolution.

Nako Nakatsuka is a senior scientist at the ETH Zürich and will start her tenure track assistant professorship at the EPFL in 2024. She was raised in Tokyo, Japan and moved to the USA for her Bachelor’s in Chemistry at Fordham University (Bronx, NY). She then pursued her Ph.D. in Physical Chemistry (Biophysics focus) at UCLA (Los Angeles, CA) in the groups of Prof. Anne Andrews and Prof. Paul Weiss. Upon receiving the prestigious ETH Zürich postdoctoral fellowship, she moved to Switzerland to join the Laboratory of Biosensors and Bioelectronics led by Prof. Janos Voros. Her multidisciplinary research focuses on understanding the molecular interactions between DNA-based bioreceptors (aptamers) and small-molecule targets to develop innovative chemical biosensors. Her most recent biosensors integrate aptamers into nanoscale pores for the detection of neurotransmitters such as serotonin and dopamine in complex biological systems. For this work, she was named an MIT Under 35 Pioneer in 2021, received the iCanX Young Scientist award in 2022, and the ACS Nano Lectureship award in 2023. She has mentored over 40 B.S., M.S., and Ph.D. students at the ETH Zürich in diverse research projects. Dr. Nakatsuka is also passionate about social justice, outreach, and education. She was awarded the Norma Stoddart Prize for Academic Excellence and Outstanding Citizenship in 2018 for her contributions in community outreach combined with her scientific achievements. She also received the Hanson-Dow Excellence in Teaching Award for her exceptional teaching and dedication to students. She is currently an active member of the Diversity Team at ETH and has contributed to initiatives that raise awareness and spark discussion about antidiscrimination within Switzerland. She has also illustrated a children’s chemistry book: “A is for Atom: ABCs for Aspiring Chemists”. For more information about Dr. Nakatsuka’s research group, please visit their web page: https://people.epfl.ch/nako.nakatsuka?lang=en.

Dr. Nakatsuka’s Article in this issue is titled "Interfacing Aptamer-Modified Nanopipettes with Neuronal Media and Ex Vivo Brain Tissue" (DOI: 10.1021/acsmeasuresciau.3c00047)

Our research focuses on exploring the full potential of CE-MS for Single Cell Glycomics Analysis, to gain insights how glycosylation is involved in malignant processes.

Guinevere Lageveen-Kammeijer is an Assistant Professor in the Analytical Biochemistry group of the Groningen Research Institute of Pharmacy at the University of Groningen (RUG). Her research focuses on developing glyco(proteo)mic methods and to extend the analytical CE-MS portfolio, with a specific focus on Single Cell Glycomic Analysis. By integrating this data her ultimate aim is to discover new molecular mechanisms and to advance the understanding of complex diseases such as cancer. Guinevere received her BSc degree in Biotechnology - Forensic Sciences from University of Applied Science van Hall Larenstein, Leeuwarden (The Netherlands) followed by a MSc in Analytical Chemistry at the VU University, Amsterdam (The Netherlands). During her MSc internship her interests in separation platforms hyphenated with mass spectrometry were sparked and she further pursued this by a PhD in Clinical Glycomics at the Center for Proteomics and Metabolomics (CPM), Leiden University Medical Center, The Netherlands under the supervision of Prof. Manfred Wuhrer. Her thesis focused on the development of small scale sample preparation workflows by CE-MS/MS to enable the in-depth analysis of glycans, glycopeptides and intact glycoproteins in complex clinical samples for biomarker discover as well for the characterization of biopharmaceuticals. In 2017 she visited the Chemistry and Chemical Biology Department at Barnett Institute at Northeastern University, Boston, MA, to develop CE-MS approaches for the characterization of protein heterogeneity under the supervision of Prof. Alexander R. Ivanov. After obtaining her PhD in 2019, she continued her research in the field of glyco(proteo)mics as a postdoctoral researcher at the CPM and in 2022, she joined RUG as a tenure track assistant professor. The significance of her work is demonstrated by her excellent track record in the Analytical Chemistry field. She received an Investigator Sponsored Research grant (Astellas) in 2019 and the prestigious NWO VENI personal grant in 2023. For more information about Dr. Lageveen-Kammeijer’s research group, please visit their web page: https://www.rug.nl/staff/g.s.m.kammeijer/.

Dr. Lageveen-Kammeijer’s Article in this issue titled "In-depth Glycoproteomic Assay of Urinary Prostatic Acid Phosphatase" (DOI: 10.1021/acsmeasuresciau.3c00055).

We are dedicated to developing responsive probes and theranostic nanotechnologies to provide solutions for current challenges in the diagnosis and treatment of diseases.

Run Zhang is Senior Research Fellow, Leader of Sensing and Imaging Group at the Australian Institute for Bioengineering and Nanotechnology (AIBN) and has a joint appointment of Food-Nano-Innovation Group Leader with the Centre for Nutrition and Food Sciences, Queensland Alliance for Agriculture and Food Innovation (CNFS, QAAFI), The University of Queensland (UQ). After completing his Ph.D. in of Analytical Chemistry in 2012 in the Dalian University of Technology, he moved to the Physics and Astronomy Department, Macquarie University (MQ) as Postdoctoral Fellow. He was awarded Macquarie University Research Fellowship in 2013 and started to build independent career in Australia in the department of Chemistry and Biomolecular Science, MQ. He joined AIBN UQ in 2016 and received Australian Research Council Discovery Early Career Researcher Award (ARC DECRA) in 2017 and National Health and Medical Research Council (NHMRC) Emerging Leadership in 2020. He now leads a team working on the development of responsive molecules/nanomaterials for biosensing and imaging, early disease detection and treatment, food, agriculture, and environmental analysis. For more information about Dr. Zhang’s research group, please visit their web page: https://researchers.uq.edu.au/researcher/16754.

Dr. Zhang’s Review in this issue titled "Advances and Perspectives of Responsive Probes for Measuring γ-Glutamyl Transpeptidase" (DOI: 10.1021/acsmeasuresciau.3c00045).

By combining lipidomics and metabolomics into a single method, we are able to provide more information for the identification of bacteria species in less time.

Kelly Hines is an Assistant Professor in the Department of Chemistry at the University of Georgia. Kelly graduated from the University of Florida in 2009 with a B.S. in Chemistry. She completed her Ph.D. in Chemistry at Vanderbilt University with John A. McLean, where she used ion mobility-mass spectrometry (IM-MS) to identify metabolite, lipid, and peptide signatures of disease from complex biological samples. After receiving her Ph.D. in 2014, Kelly completed a one-year postdoctoral fellowship in the Mayo Clinic Regional Metabolomics Core where she established quantitative MS methods for lipidomics and protein metabolism. In 2015, Kelly joined the lab of Libin Xu at the University of Washington School of Pharmacy. Her work in the Xu Lab, supported in part by a U.S. Pharmacopeial Convention (USP) Global Fellowship, focused on high-throughput IM-MS measurements of drugs and small molecules, and LC-IM-MS methods for lipidomics. She joined the faculty at UGA in 2019, where her lab is using chromatographic separations and ion mobility-mass spectrometry to detect and investigate antibiotic resistance in bacterial pathogens. Kelly has been recognized as a Female Role Model in Analytical Chemistry by Analytical and Bioanalytical Chemistry, an Outstanding Emerging Investigator by the Journal of the American Society for Mass Spectrometry, and is the recipient of an ASMS Research Award. For more information about Dr. Hines’ research group, please visit their web page: www.thehineslab.com.

Dr. Hines’ Article in this issue titled "HILIC-IM-MS for Simultaneous Lipid and Metabolite Profiling of Bacteria" (DOI: 10.1021/acsmeasuresciau.3c00051)

The development of paper-based electrochemical sensors and biosensors will allow nonspecialists to get quicker answers for societal needs.

Stefano Cinti is an Associate Professor at the Department of Pharmacy, University of Naples “Federico II”. He obtained a Ph.D. in Chemical Sciences in 2016 in the group headed by Prof. Giuseppe Palleschi at the University of Rome “Tor Vergata”. He leads the uninanobiosensors Lab (uninanobiosensors.com) at University of Naples “Federico II”, and his research interests include the development of electrochemical sensors, portable diagnostics, paper-based devices and nanomaterials. During his research activity, he had the opportunity to spend a period abroad in Finland, U.K., USA, Germany, and Spain. Among his prizes and certificates, in 2018 he was named Best Young Researcher in Bio-Analytical Chemistry, in 2019 he was named Best Young Researcher in Analytical Chemistry (both by the Italian Chemical Society), in 2022 he was awarded with the early career award from International Society of Electrochemistry (ISE) in Analytical Electrochemistry, in 2022 he was awarded with Biosensors Young Investigator Award, and in 2023 he was awarded Sensor Division Early Career Award by The Electrochemical Society (ECS). He is the coordinator of the Chemical Cultural Diffusion group of Italian Chemical Society. He is the Chair of AMYC-BIOMED, a multidisciplinary conference for young chemists in the biomedical sciences. He is very active in communicating science to nonspecialized audiences through TV shows, radio, and magazine. For more information about Dr. Cinti’s research group, please visit their web page: https://uninanobiosensors.com/people/.

Dr. Cinti’s Article in this issue is titled "Technical Evaluation of a Paper-Based Electrochemical Strip to Measure Nitrite Ions in the Forensic Field" (DOI: 10.1021/acsmeasuresciau.3c00050).

Pyrolysis of polydopamine can tune the surface chemistry of porous paper-based carbon-based electrodes for electrochemical applications in the field of biosensors.

Murilo Santhiago is a researcher at the Brazilian Nanotechnology National Laboratory (LNNano), located in the Brazilian Center for Research in Energy and Materials (CNPEM) in Campinas, SP, Brazil. He obtained his bachelors degree in chemistry in 2007 in the Federal University of Santa Catarina (UFSC), Florianópolis-SC, Brazil. Next, he moved to Campinas-SP, Brazil to pursue his masters and Ph.D. (2014) in chemistry in Campinas State University (UNICAMP) under the guidance of Prof. Dr. Lauro T. Kubota. Under the same supervisor he was a postdoctoral researcher (2014–2015) working with microfluidics and 2D materials for electrochemical applications. He was a visiting researcher at International Iberian Nanotechnology Laboratory (INL) in 2019, Braga-Pt, working with Prof. Lifeng Liu to develop better electrodes for energy applications. In 2020 he was awarded a grant by the Serrapilheira Institute who provides financial support thorough an extremely competitive application process to young researchers that are committed to addressing fundamental. His current research interest are flexible electrochemical nanodevices, paper-based devices, micronanofabrication and 2D materials with applications in energy, environmental, and health fields. One of my goals is to stimulate students creativity and guide them to solve relevant problems of our society by exploring the amazing field of nanotechnology. For more information about Dr. Santhiago’s research group, please visit their web page: https://lnnano.cnpem.br/instalacoes-e-divisoes/divisao-de-dispositivos/equipe/murilo-santhiago/.

Dr. Santhiago’s Article in this issue is titled "Tuning the Chemical and Electrochemical Properties of Paper-Based Carbon Electrodes by Pyrolysis of Polydopamine" (DOI: 10.1021/acsmeasuresciau.3c00063).

My research goal is to develop intelligent diagnostic devices by integrating functional nanomaterials with artificial intelligence, smartphone technology, and miniaturized electronics.

Veerappan Mani is a research scientist in the Sensors Laboratory at King Abdullah University of Science and Technology (KAUST), Saudi Arabia. Before joining KAUST, he worked as a research assistant professor at Taipei Tech, Taiwan from 2016 to 2019. He was a visiting scientist at the University of California, Santa Barbara (UCSB), USA in 2023. In 2014, he received his Ph.D. in Analytical Chemistry from the National Taipei University of Technology (NTUT), Taiwan, under the supervision of Prof. Shen-Ming Chen. He received his Master’s and Bachelor’s degrees in Chemistry from Bharathidasan University and Periyar University, India, respectively. His research work focuses on the development of sensor materials and integrated devices for diagnostic applications, with particular focus on cardiovascular diseases and neurodegenerative disorders. He develops real-time in situ sensors for precision medicine, 2D materials and single-atom nanozymes for signal amplifications, advanced biosensors integrating machine learning, point-of-care devices using smartphone integration, hydrogels-based microneedles for wearable sensors, and stimuli-responsive redox substrates. He serves as Editorial board Member for International Journal of Molecular Sciences, Frontiers in Materials, Micromachines, Frontiers in Chemistry, and Frontiers in Electronics. For more information about Dr. Mani’s research group, please visit their web page: https://cemse.kaust.edu.sa/sensors/people/person/veerappan-mani.

Dr. Mani’s Review in this issue is titled "Self-Immolative Electrochemical Redox Substrates: Emerging Artificial Receptors in Sensing and Biosensing" (DOI: 10.1021/acsmeasuresciau.3c00057).

My research will significantly advance measurement science by filling critical gaps in structural characterization, enabling more precise analyses, and accelerating the discovery of novel chemistry.

Xin Yan is currently an Assistant Professor in the Department of Chemistry at Texas A&M University. She received her Ph.D. in Chemistry under the guidance of Professor Graham Cooks at Purdue University in 2015 after she earned her B.S. in Pharmacy from Fudan University. From 2016 to 2018, Xin joined Professor Richard Zare’s lab at Stanford University to pursue her postdoctoral studies. Her current research focuses on the development of microdroplet mass spectrometry and its applications to address deficiencies in “-omics” studies and expedite the discovery process in transition metal catalysis. For example, her group developed a voltage-controlled interfacial microreactor that allows acceleration of electrochemical reactions for the first time which has been used to address various long-standing isomeric problems in lipidomics. She also developed a novel mass spectrometry screening platform that uses picomole-scale anodic corrosion of transition metal electrodes to enable the rapid discovery of transition metal catalysis. For more information about Dr. Yan’s research group, please visit their web page: https://www.chem.tamu.edu/faculty/xin-yan/.

Dr. Yan’s Article in this issue is titled "Lipid Isobaric Mass Tagging for Enhanced Relative Quantification of Unsaturated sn-Positional Isomers" (DOI: 10.1021/acsmeasuresciau.3c00062).

In the charge-carriers’ silent ballet, transient spectroscopy and microscopy reveal ephemeral choreography, painting unseen finesse within materials─a delicate canvas in material science.

Sachin Dev Verma, currently an Assistant Professor at the Department of Chemistry, Indian Institute of Science Education and Research (IISER) Bhopal, India, is a dedicated researcher whose work centers on developing spectroscopic and microscopic methods to understand dynamics at nanoscale. His research delves into understanding excited state processes, charge-carrier dynamics, thermalization, and their correlation with spatial heterogeneity in molecular and inorganic semiconductors. Beginning his academic journey with a bachelor’s degree in physics from Bundelkhand University in 2003, Dr. Verma pursued a Ph.D. from School of Physical Sciences at Jawaharlal Nehru University, New Delhi, under the guidance of Prof. Sobhan Sen (2006–2013). He successfully completed his doctoral studies focusing on molecular interactions and ultrafast dynamics in DNA. Following his Ph.D., Dr. Verma refined his expertise through various postdoctoral positions. As a Postdoctoral Fellow at the Department of Chemistry and Biochemistry, University of South Carolina, USA (April 2013–February 2016), he developed multidimensional analysis methods to uncover the origin of relaxation rate dispersion in complex systems. Subsequently, as a Postdoctoral Scholar at the Department of Chemistry, University of California, Irvine, USA (March 2016–August 2017), he utilized two-dimensional infrared spectroscopy to understand molecular dynamics in biological molecules. His international research continued as a Marie Skłodowska-Curie Fellow at the Cavendish Laboratory, University of Cambridge, UK (September 2017–August 2019) where he employed transient absorption spectroscopic and microscopic techniques to understand charge carrier dynamics in semiconductors. Dr. Verma extended his collaboration with Prof. Akshay Rao, working as a Research Associate at the same institution from September 2019 to December 2019. Dr. Verma’s diverse research journey underscores his commitment to advancing understanding at nanoscale. As an Assistant Professor at IISER Bhopal, he significantly contributes to the academic and scientific community, inspiring the next generation of researchers in materials science and optoelectronics. For more information about Dr. Verma’s research group, please visit their web page: https://sites.google.com/view/sdvlabs/hola.

Dr. Verma’s Perspective in this issue is titled "Two-Dimensional Fluctuation Correlation Spectroscopy (2D-FluCS): A Method to Determine the Origin of Relaxation Rate Dispersion" (DOI: 10.1021/acsmeasuresciau.3c00048).

Automated characterization is essential for objective-driven autonomous laboratories. Our work develops AI-infrastructures and integrates large AI copilots to automate chemical and biological laboratories.

Gaurav Chopra is a tenured Associate Professor in the Departments of Chemistry and Computer Science at Purdue University. As the Director of the Merck-Purdue Center, an initiative supported by Merck, Chopra oversees projects spanning Purdue University. His research group (http://www.chopralab.com) is at the forefront of Molecular Artificial Intelligence focused on identifying and targeting immuno-metabolic “brakes” to understand glial and immune dysfunction in neurodegeneration and cancer. The Chopra group stands out globally for employing a multidisciplinary approach to develop bioanalytical methods, chemical tools, targeted drugs, and artificial intelligence (AI) platforms with closed-loop laboratory automation and conducting experimental validations in cancer- and neuro-immunology. Chopra received his undergraduate degree in Mechanical Engineering in 2002 from the Indian Institute of Technology, Delhi, India and his M.S. in 2003 in Mechanical Engineering from the University of California, Irvine. In 2010, Chopra received his Ph.D. in Computational Mathematics with Professor Michael Levitt (2013 Nobel Laureate in Chemistry) at Stanford University School of Engineering and was a JDRF Fellow from 2012 to 2016 in experimental immunology developing immune tolerance therapies with Professor Jeffrey Bluestone at the University of California─San Francisco, School of Medicine. Chopra’s research program is funded by several federal agencies and companies. Recently, Chopra led a team that won the ASPIRE Grand Prize by the National Center for Advancing Translational Science (NCATS) for developing AI-guided drug discovery and automation platform. His current work with NCATS includes developing large language model-based AI infrastructure to plan, execute, analyze and automate chemical and biological experiments to accelerate drug discovery and development. Outside of academia, Chopra has cofounded two companies─Meditati Inc. and BrainGnosis Inc. Chopra is dedicated to fostering diversity in academia, developed a virtual reality-based drug discovery game, MINT, and organized outreach events for K-12 and university students, promoting a love for science and inclusivity in scientific endeavors. For more information about Dr. Chopra’s research group, please visit their web page: https://www.chem.purdue.edu/people/profile/gchopra.

Dr. Chopra’s Review in this issue is titled "Recent Developments in Machine Learning and Artificial Intelligence for Mass Spectrometry" (DOI: 10.1021/acsmeasuresciau.3c00060).

Yours sincerely,

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