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    Stretchable Electronic Facial Masks for Sonophoresis
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    • Shuang Li
      Shuang Li
      State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
      School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
      More by Shuang Li
    • Jingwen Xu
      Jingwen Xu
      State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
      University of Chinese Academy of Sciences, Beijing 100049, China
      More by Jingwen Xu
    • Rui Li
      Rui Li
      State Key Laboratory of Structural Analysis for Industrial Equipment, Department of Engineering Mechanics, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian 116024, China
      More by Rui Li
    • Yongkang Wang
      Yongkang Wang
      State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
      School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
      More by Yongkang Wang
    • Maoyi Zhang
      Maoyi Zhang
      State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
      School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
      More by Maoyi Zhang
    • Jie Li
      Jie Li
      Institute for Advanced Ceramics, State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150001, China
      More by Jie Li
    • Shizhen Yin
      Shizhen Yin
      State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
      School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
      More by Shizhen Yin
    • Guodong Liu
      Guodong Liu
      State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
      School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
      More by Guodong Liu
    • Lijuan Zhang
      Lijuan Zhang
      State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
      School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
      More by Lijuan Zhang
    • Baoqiang Li
      Baoqiang Li
      Institute for Advanced Ceramics, State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150001, China
      More by Baoqiang Li
      Orcidhttps://orcid.org/0000-0003-0278-4542
    • Qi Gu
      Qi Gu
      State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
      University of Chinese Academy of Sciences, Beijing 100049, China
      Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China
      More by Qi Gu
      Orcidhttps://orcid.org/0000-0001-9387-9525
    • Yewang Su*
      Yewang Su
      State Key Laboratory of Nonlinear Mechanics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190, China
      School of Engineering Science, University of Chinese Academy of Sciences, Beijing 100049, China
      State Key Laboratory of Acoustics, Institute of Acoustics, Chinese Academy of Sciences, Beijing 100190, China
      *E-mail: [email protected]
      More by Yewang Su
      Orcidhttps://orcid.org/0000-0002-5961-0490
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    ACS Nano

    Cite this: ACS Nano 2022, 16, 4, 5961–5974
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    https://doi.org/10.1021/acsnano.1c11181
    Published April 1, 2022
    Copyright © 2022 American Chemical Society
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    Abstract

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    We introduce a stretchable electronic facial mask (SEFM) as a platform for facial healthcare, which can integrate with various sensors and actuators. As a demonstration, an SEFM for sonophoresis enabling the promotion of the delivery effect of a drug mask is developed. To overcome the technique challenges, several approaches including the design of the joined silicone layer by two planar half-face portions and the single-side soft pressing (SSSP) technique for encapsulation are exploited in this work, which could be extended to the design and fabrication of other stretchable electronics. The mechanical, thermal, electrical, and ultrasonic characteristics of the SEFM are all verified by the finite element analysis and experiments. Finally, we prove the effect of the SEFM on accelerating the delivery of hyaluronic acid (HA) through animal experiments and confirm that the SEFM can enhance the skin moisture content by 20% via human facial experiments.

    Copyright © 2022 American Chemical Society

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    Supporting Information

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    The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acsnano.1c11181.

    • The visual effect that the SEFM emits ultrasound to a water drop (MP4)

    • The visual effect that the SEFM emits ultrasound to 3 × 3 water drops (MP4)

    • Establishment process of the face-like silicone layer by FEA; calculation of the bending and tensile stiffnesses; theoretical modeling of one-dimensional piezoelectric vibrator; tensile test of the rectangular sample of the SEFM; material parameters in the FEA; geometric model and meshes in the FEA of sound field; simulated results of sound field; detailed statistical data; detailed layout of the island-bridge mesh circuit; details on the encapsulation process; robustness of the mechanical and electrical properties; more impedance–frequency curves; more confocal micrographs; experiment on thermal effect; delivery of beta-glucan and d-panthenol (PDF)

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    ACS Nano

    Cite this: ACS Nano 2022, 16, 4, 5961–5974
    Click to copy citationCitation copied!
    https://doi.org/10.1021/acsnano.1c11181
    Published April 1, 2022
    Copyright © 2022 American Chemical Society
    Request reuse permissions

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