Dihydrolevoglucosenone (Cyrene) as a Biobased Green Alternative to Organic Solvents for the Preparation of Supramolecular Gels Consisting of Self-Assembling Dipeptide DerivativesClick to copy article linkArticle link copied!
- Shintaro SugiuraShintaro SugiuraDepartment of Life Science and Chemistry, Graduate School of Natural Science and Technology, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanUnited Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanMore by Shintaro Sugiura
- Yuki ShintaniYuki ShintaniUnited Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanMore by Yuki Shintani
- Sayuri L. HigashiSayuri L. HigashiUnited Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanInstitute of Advanced Study, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanCenter for One Medicine Innovative Translational Research (COMIT), Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanMore by Sayuri L. Higashi
- Aya ShibataAya ShibataDepartment of Life Science and Chemistry, Graduate School of Natural Science and Technology, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanMore by Aya Shibata
- Masato Ikeda*Masato Ikeda*E-mail: [email protected]Department of Life Science and Chemistry, Graduate School of Natural Science and Technology, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanUnited Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanCenter for One Medicine Innovative Translational Research (COMIT), Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanInstitute for Glyco-core Research (iGCORE), Gifu University, 1-1 Yanagido, Gifu 501-1193, JapanInstitute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, JapanMore by Masato Ikeda
Abstract

Herein, we describe the use of Cyrene, a biobased green solvent, to prepare supramolecular gels composed of self-assembling dipeptide derivatives. The gelation behavior was evaluated by using a conventional tube-inversion method. The basic properties, of the obtained supramolecular gels, including critical gel concentrations and viscoelastic properties, were assessed. In addition, the self-assembled fibrous network inside the gels was investigated via confocal laser scanning microscopy after fluorescence staining. The results offer important insights into the preparation of supramolecular gel-based materials with minimal environmental damage for practical applications.
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