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Ion Pair Driven Self-Assembly of a Flexible Bis-Zwitterion in Polar Solution:  Formation of Discrete Nanometer-Sized Cyclic Dimers

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University of Würzburg, Institute of Organic Chemistry, Am Hubland, 97074 Würzburg, Germany, and Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany
Cite this: J. Am. Chem. Soc. 2006, 128, 5, 1430–1431
Publication Date (Web):January 13, 2006
https://doi.org/10.1021/ja056465c
Copyright © 2006 American Chemical Society
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    Abstract

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    The self-complementary flexible bis-zwitterion 1 forms discrete nanometer-sized cyclic dimers via ion pair driven self-assembly even in polar solvents. The existence of such dimers was confirmed by DOSY NMR, FAB-MS, and scattering experiments (DLS, SANS) which all indicate the concentration-dependent formation of cyclic dimers with a hydrodynamic radius of rH ≈ 2.5 nm in solution.

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    In papers with more than one author, the asterisk indicates the name of the author to whom inquiries about the paper should be addressed.

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     University of Würzburg.

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     Max Planck Institute for Polymer Research.

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    Details on the synthesis, the NMR, DOSY, ESI-MS, DLS, and SANS experiments and the molecular mechanics calculations.

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