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Palladium-Catalyzed Carboiodination of Alkenes: Carbon−Carbon Bond Formation with Retention of Reactive Functionality

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Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, Canada M5S 3H6
Cite this: J. Am. Chem. Soc. 2011, 133, 6, 1778–1780
Publication Date (Web):January 25, 2011
https://doi.org/10.1021/ja110377q
Copyright © 2011 American Chemical Society

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    Abstract

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    We report a palladium-catalyzed carbon−carbon bond-forming reaction between aryl iodides and alkenes. In contrast to traditional cross-coupling reactions, two new bonds are formed, and all of the atoms in the starting materials are incorporated into the product. The use of a palladium catalyst with bulky phosphine ligands is found to be crucial for reactivity.

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    Experimental procedures and spectral data for all new compounds. This material is available free of charge via the Internet at http://pubs.acs.org.

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