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Asymmetric Diels−Alder Reactions of Chiral 1-Amino-3-siloxy-1,3-butadiene:  Application to the Enantioselective Synthesis of (−)-α-Elemene

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Department of Chemistry The University of Chicago Chicago, Illinois 60637
Cite this: J. Am. Chem. Soc. 1997, 119, 30, 7165–7166
Publication Date (Web):July 30, 1997
Copyright © 1997 American Chemical Society

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    60. K. C. Nicolaou, G. Scott Tria, David J. Edmonds. Total Synthesis of Platencin. Angewandte Chemie 2008, 120 (9) , 1804-1807.
    61. K. C. Nicolaou, G. Scott Tria, David J. Edmonds. Total Synthesis of Platencin. Angewandte Chemie International Edition 2008, 47 (9) , 1780-1783.
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    63. Masato Koreeda, Peter D. Wilson, Michael P. A. Lyle. 4-Methoxy-3-buten-2-one. 2007
    64. Shuji Hirano, Yasuhiro Fukudome, Ryoichi Tanaka, Fumie Sato, Hirokazu Urabe. Practical preparation of N-(1-alkynyl)sulfonamides and their synthetic utility in titanium alkoxide-mediated coupling reactions. Tetrahedron 2006, 62 (16) , 3896-3916.
    65. Anthony R. Lingham, Helmut M. Hügel, Trevor J. Rook. Diels - Alder Reactions of 3-Furylamines in Organic and Aqueous Solvents. Australian Journal of Chemistry 2006, 59 (5) , 336.
    66. Kerrie L. Burgess, Matthew S. Corbett, Paul Eugenio, Neil J. Lajkiewicz, Xiang Liu, Amitav Sanyal, Wanlin Yan, Qian Yuan, John K. Snyder. Chiral anthracene and anthrone templates as stereocontrolling elements in Diels–Alder/retro Diels–Alder sequences. Bioorganic & Medicinal Chemistry 2005, 13 (17) , 5299-5309.
    67. Amitav Sanyal, Qian Yuan, John K. Snyder. A new, chiral aminoanthracene for the Diels–Alder/retro-Diels–Alder sequence in lactam and butenolide synthesis. Tetrahedron Letters 2005, 46 (14) , 2475-2478.
    68. I. A. Maretina. 4,4-Dialkoxybutan-2-ones as Synthons. Russian Journal of Organic Chemistry 2005, 41 (1) , 1-27.
    69. José Barluenga, Fernando Aznar, Patricia Moriel, Carlos Valdés. Palladium‐Catalyzed Amination of 1‐Bromo‐ and 1‐Chloro‐1,3‐butadienes: A General Method for the Synthesis of 1‐Amino‐1,3‐butadienes. Advanced Synthesis & Catalysis 2004, 346 (13-15) , 1697-1701.
    70. Sergey A. Kozmin, Shuwen He, Viresh H. Rawal. Preparation of (E)‐1‐Dimethylamino‐3‐tert‐Butyldimethylsiloxy‐1,3‐Butadiene. 2003, 152-152.
    71. Sergey A. Kozmin, Shuwen He, Viresh H. Rawal. [4 + 2] Cycloaddition of 1‐Dimethylamino‐3‐tert‐Butyldimethylsiloxy‐1,3‐Butadiene with Methyl Acrylate: 4‐Hydroxymethyl‐2‐Cyclohexen‐1‐One. 2003, 160-160.
    72. Maria C. Aversa, Anna Barattucci, Paola Bonaccorsi, Placido Giannetto. An investigation of the behaviour of α,β-unsaturated sulfoxides in the presence of trimethylsilyl iodide. Tetrahedron 2002, 58 (51) , 10145-10150.
    73. Norito Takenaka, Yong Huang, Viresh H. Rawal. The first catalytic enantioselective Diels–Alder reactions of 1,2-dihydropyridine: efficient syntheses of optically active 2-azabicyclo[2.2.2]octanes with chiral BINAM derived Cr(III) salen complexes. Tetrahedron 2002, 58 (41) , 8299-8305.
    74. Yu-ichi Fukuda, Hiroyuki Sasaki, Mitsuru Shindo, Kozo Shishido. Diastereoselective ring-closing metathesis for the construction of a quaternary carbon stereogenic center. Tetrahedron Letters 2002, 43 (11) , 2047-2049.
    75. José Barluenga, Francisco J Fañanás. Metalloxy Fischer Carbene Complexes: An Efficient Strategy to Modulate Their Reactivity. Tetrahedron 2000, 56 (27) , 4597-4628.
    76. Maria C Aversa, Anna Barattucci, Paola Bonaccorsi, Giuseppe Bruno, Placido Giannetto, Manuela Policicchio. Unexpected conversion of vinyl sulfoxides into carbonyl compounds by means of iodotrimethylsilane. Tetrahedron Letters 2000, 41 (22) , 4441-4445.
    77. Hiroaki Miyaoka, Yasuhiro Kajiwara, Miho Hara, Akira Suma, Yasuji Yamada. Synthesis of optically active 3-alkoxy-6-hydroxymethyl-6-methyl-2-cyclohexenone. Tetrahedron: Asymmetry 1999, 10 (16) , 3189-3196.
    78. Takeshi Hanamoto, Nami Shimomoto, Takashi Kikukawa, Junji Inanaga. Efficient synthesis of enantiomerically pure trans-2,5-bis(arylethynyl)pyrrolidines. A new entry into C2-symmetric chiral secondary amines. Tetrahedron: Asymmetry 1999, 10 (15) , 2951-2959.
    79. Jean-Luc Renaud, Corinne Aubert, Max Malacria. Synthesis of a new versatile dienophile and its use in a highly diastereoselective Diels-Alder reaction. Tetrahedron Letters 1999, 40 (27) , 5015-5018.
    80. Marina Virgili, Albert Moyano, Miquel A. Pericàs, Antoni Riera. Chiral (E,E)-1,4-dialkoxy-1,3-butadienes. 2. Conformational studies and Diels-Alder reactions with symmetric dienophiles. Tetrahedron 1999, 55 (13) , 3959-3986.
    81. Colin P. Dell. Cycloadditions in synthesis. Journal of the Chemical Society, Perkin Transactions 1 1998, 50 (22) , 3873.
    82. Paul J. Stevenson. Chapter 2. Synthetic methods . Part (ii) Pericyclic methods. Annual Reports Section "B" (Organic Chemistry) 1998, 94 , 19.
    83. S. A. KOZMIN, V. H. RAWAL. ChemInform Abstract: Asymmetric Diels‐Alder Reactions of Chiral 1‐Amino‐3‐siloxy‐1,3‐ butadiene: Application to the Enantioselective Synthesis of (‐)‐α ‐Elemene.. ChemInform 1997, 28 (48)
    84. Roberto Fernández de la Pradilla, María Victoria^Martínez, Carlos Montero, Alma Viso. Sulfur-directed synthesis of enantiopure hydroxy 2-sulfinyl butadienes. Tetrahedron Letters 1997, 38 (44) , 7773-7776.

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