ACS Publications. Most Trusted. Most Cited. Most Read
My Activity
CONTENT TYPES

Figure 1Loading Img

Kinetics-Controlled Super-Assembly of Asymmetric Porous and Hollow Carbon Nanoparticles as Light-Sensitive Smart Nanovehicles

  • Lei Xie
    Lei Xie
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Lei Xie
  • Miao Yan
    Miao Yan
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Miao Yan
  • Tianyi Liu
    Tianyi Liu
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Tianyi Liu
  • Ke Gong
    Ke Gong
    State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200032, P. R. China
    More by Ke Gong
  • Xin Luo
    Xin Luo
    School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, P. R. China
    More by Xin Luo
  • Beilei Qiu
    Beilei Qiu
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Beilei Qiu
  • Jie Zeng
    Jie Zeng
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Jie Zeng
  • Qirui Liang
    Qirui Liang
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Qirui Liang
  • Shan Zhou
    Shan Zhou
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Shan Zhou
  • Yanjun He
    Yanjun He
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Yanjun He
  • Wei Zhang
    Wei Zhang
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    More by Wei Zhang
  • Yilan Jiang
    Yilan Jiang
    School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, P. R. China
    More by Yilan Jiang
  • Yi Yu
    Yi Yu
    School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, P. R. China
    More by Yi Yu
  • Jinyao Tang
    Jinyao Tang
    Department of Chemistry, The University of Hong Kong, Hong Kong 999077, P. R. China
    More by Jinyao Tang
  • Kang Liang
    Kang Liang
    School of Chemical Engineering, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, NSW 2052, Australia
    More by Kang Liang
  • Dongyuan Zhao
    Dongyuan Zhao
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
  • , and 
  • Biao Kong*
    Biao Kong
    Department of Chemistry, Shanghai Key Lab of Molecular Catalysis and Innovative Materials, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200438, P. R. China
    *[email protected]
    More by Biao Kong
Cite this: J. Am. Chem. Soc. 2022, 144, 4, 1634–1646
Publication Date (Web):January 11, 2022
https://doi.org/10.1021/jacs.1c10391
Copyright © 2022 American Chemical Society

    Article Views

    9405

    Altmetric

    -

    Citations

    LEARN ABOUT THESE METRICS
    Other access options
    Supporting Info (11)»

    Abstract

    Abstract Image

    The rational design and controllable synthesis of hollow nanoparticles with both a mesoporous shell and an asymmetric architecture are crucially desired yet still significant challenges. In this work, a kinetics-controlled interfacial super-assembly strategy is developed, which is capable of preparing asymmetric porous and hollow carbon (APHC) nanoparticles through the precise regulation of polymerization and assembly rates of two kinds of precursors. In this method, Janus resin and silica hybrid (RSH) nanoparticles are first fabricated through the kinetics-controlled competitive nucleation and assembly of two precursors. Specifically, silica nanoparticles are initially formed, and the resin nanoparticles are subsequently formed on one side of the silica nanoparticles, followed by the co-assembly of silica and resin on the other side of the silica nanoparticles. The APHC nanoparticles are finally obtained via high-temperature carbonization of RSH nanoparticles and elimination of silica. The erratic asymmetrical, hierarchical porous and hollow structure and excellent photothermal performance under 980 nm near-infrared (NIR) light endow the APHC nanoparticles with the ability to serve as fuel-free nanomotors with NIR-light-driven propulsion. Upon illumination by NIR light, the photothermal effect of the APHC shell causes both self-thermophoresis and jet driving forces, which propel the APHC nanomotor. Furthermore, with the assistance of phase change materials, such APHC nanoparticles can be employed as smart vehicles that can achieve on-demand release of drugs with a 980 nm NIR laser. As a proof of concept, we apply this APHC-based therapeutic system in cancer treatment, which shows improved anticancer performance due to the synergy of photothermal therapy and chemotherapy. In brief, this kinetics-controlled approach may put forward new insight into the design and synthesis of functional materials with unique structures, properties, and applications by adjusting the assembly rates of multiple precursors in a reaction system.

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. You can change your affiliated institution below.

    Supporting Information

    ARTICLE SECTIONS
    Jump To

    The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/jacs.1c10391.

    • Detailed description of step 1 in Figure 1; Figures S1–S39, including SEM and TEM images, spectra, TGA curves, XRD patterns, and additional plots, models, and discussions; and Table S1, listing the elemental content of samples (PDF)

    • Video S1: APHC nanoparticles tracking in water without NIR light (MP4)

    • Video S2: APHC nanoparticles tracking in water with 1.0 W cm–2 NIR light (MP4)

    • Video S3: APHC nanoparticles tracking in water with 2.0 W cm–2 NIR light (MP4)

    • Video S4: APHC nanoparticles tracking in water with 3.0 W cm–2 NIR light (MP4)

    • Video S5: silica nanospheres tracking in water without NIR light (MP4)

    • Video S6: silica nanospheres tracking in water with 2.0 W cm–2 NIR light (MP4)

    • Video S7: porous carbon nanospheres tracking in water without NIR light (MP4)

    • Video S8: porous carbon nanospheres tracking in water with 2.0 W cm–2 NIR light (MP4)

    • Video S9: CSH nanoparticles tracking in water without NIR light (MP4)

    • Video S10: CSH nanoparticles tracking in water with 2.0 W cm–2 NIR light (MP4)

    Terms & Conditions

    Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses). Permission may be obtained from ACS for other uses through requests via the RightsLink permission system: http://pubs.acs.org/page/copyright/permissions.html.

    Cited By

    This article is cited by 41 publications.

    1. Kexin Lv, Mengmeng Hou, Yufang Kou, Hongyue Yu, Mengli Liu, Tiancong Zhao, Jiacheng Shen, Xirui Huang, Jie Zhang, Mohamed F. Mady, Ahmed A. Elzatahry, Xiaomin Li, Dongyuan Zhao. Black Titania Janus Mesoporous Nanomotor for Enhanced Tumor Penetration and Near-Infrared Light-Triggered Photodynamic Therapy. ACS Nano 2024, Article ASAP.
    2. Jie Zeng, Lei Xie, Tianyi Liu, Yanjun He, Weiyan Liu, Qing Zhang, Junyan Li, Xiaofeng Li, Beilei Qiu, Shan Zhou, Qirui Liang, Xudong Wang, Kang Liang, Jinyao Tang, Jian Liu, Lei Jiang, Gang Huang, Biao Kong. Super-Assembled Multilayered Mesoporous TiO2 Nanorockets for Light-Powered Space-Confined Microfluidic Catalysis. ACS Applied Materials & Interfaces 2024, 16 (18) , 23484-23496. https://doi.org/10.1021/acsami.3c19302
    3. Jueyi Xue, Mengnan Zhang, Joel Yong, Qianfan Chen, Joseph Wang, Jiangtao Xu, Kang Liang. Light-Switchable Biocatalytic Covalent–Organic Framework Nanomotors for Aqueous Contaminants Removal. Nano Letters 2023, 23 (23) , 11243-11251. https://doi.org/10.1021/acs.nanolett.3c03766
    4. Shuoshuo Lv, Tao Hong, Menghui Wan, Lichao Peng, Yanbao Zhao, Lei Sun, Xueyan Zou. Multifunctional Mesoporous Silica Nanosheets for Smart Pesticide Delivery and Enhancing Pesticide Deposition. Langmuir 2023, 39 (36) , 12807-12816. https://doi.org/10.1021/acs.langmuir.3c01661
    5. Haina Tian, Yang Li, Jinyan Lin, Fukai Zhu, Zhenqing Hou, Peiyuan Wang, Xiaolong Liu. Programmed Nanoreactors Boost Immune Response through ROS Cascade Amplification along with RNS Storm. ACS Materials Letters 2023, 5 (9) , 2542-2555. https://doi.org/10.1021/acsmaterialslett.3c00676
    6. Zhanlin Zhang, Hui Yan, Wenxiong Cao, Shuang Xie, Pan Ran, Kun Wei, Xiaohong Li. Ultrasound-Chargeable Persistent Luminescence Nanoparticles to Generate Self-Propelled Motion and Photothermal/NO Therapy for Synergistic Tumor Treatment. ACS Nano 2023, 17 (16) , 16089-16106. https://doi.org/10.1021/acsnano.3c04906
    7. Sijia Wang, Lu Hou, Wen-Cui Li, Shuang Xu, Rui-Ping Zhang, An-Hui Lu. Asymmetrically Distributed Tween-80-Induced Edge-Preferential Polymerization of Benzoxazine toward Selective Fabrication of Donut-Shaped Polymer and Carbon Nanodiscs. Chemistry of Materials 2023, 35 (13) , 5100-5107. https://doi.org/10.1021/acs.chemmater.3c00701
    8. Abuduheiremu Awati, Shan Zhou, Ting Shi, Jie Zeng, Ran Yang, Yanjun He, Xin Zhang, Hui Zeng, Dazhang Zhu, Tongcheng Cao, Lei Xie, Mingxian Liu, Biao Kong. Interfacial Super-Assembly of Intertwined Nanofibers toward Hybrid Nanochannels for Synergistic Salinity Gradient Power Conversion. ACS Applied Materials & Interfaces 2023, 15 (22) , 27075-27088. https://doi.org/10.1021/acsami.3c03464
    9. Fu-Rong Zeng, Bo-Wen Liu, Zi-Hao Wang, Jia-Yan Zhang, Xue-Lian Chen, Hai-Bo Zhao, Yu-Zhong Wang. Recyclable Biophenolic Nanospheres for Sustainable and Durable Multifunctional Applications in Thermosets. ACS Materials Letters 2023, 5 (6) , 1692-1702. https://doi.org/10.1021/acsmaterialslett.3c00403
    10. Wenlong Fu, Lei Xie, Jicheng Yu, Yanjun He, Jie Zeng, Jian Liu, Kang Liang, Pu Chen, Lei Jiang, Zhen Gu, Biao Kong. In Situ Interfacial Super-Assembly of Nanobiohybrids through Plant for Food-Grade Oral Medicine. ACS Applied Materials & Interfaces 2023, 15 (5) , 7282-7293. https://doi.org/10.1021/acsami.2c19791
    11. Dong Liu, Ting Zhang, Yijia Guo, Yuting Liao, Zijian Wu, Hao Jiang, Yuan Lu. Biohybrid Magnetic Microrobots for Tumor Assassination and Active Tissue Regeneration. ACS Applied Bio Materials 2022, 5 (12) , 5933-5942. https://doi.org/10.1021/acsabm.2c00880
    12. Lei Tang, Wenhao Yi, Feng Qin, Qin Fan. Switchable Nanostructures Triggered by Noyori-Type Organometallics. Inorganic Chemistry 2022, 61 (49) , 19668-19672. https://doi.org/10.1021/acs.inorgchem.2c03567
    13. Chun Liu, Jingsheng Niu, Tingting Cui, Jinsong Ren, Xiaogang Qu. A Motor-Based Carbonaceous Nanocalabash Catalyst for Deep-Layered Bioorthogonal Chemistry. Journal of the American Chemical Society 2022, 144 (42) , 19611-19618. https://doi.org/10.1021/jacs.2c09599
    14. Haoguan Gui, Tiantian Yang, Li-Li Li, Fuxin Liang, Zhenzhong Yang. Temperature-Sensitive Anti-Inflammatory Organohydrogels Containing Janus Particle Stabilized Phase-Change Microinclusions. ACS Nano 2022, 16 (6) , 9859-9870. https://doi.org/10.1021/acsnano.2c03940
    15. Shunsuke Yamada. A Transient Supercapacitor with a Water-Dissolvable Ionic Gel for Sustainable Electronics. ACS Applied Materials & Interfaces 2022, 14 (23) , 26595-26603. https://doi.org/10.1021/acsami.2c00915
    16. . Design and Preparation. 2023, 21-60. https://doi.org/10.1002/9783527839773.ch3
    17. Zhenwei Wu, Kun Zhang, Jiaming Sun, Chunhui Ma, Sha Luo, Wei Li, Shouxin Liu. Kinetics‐Controlled Synthesis of Ordered Mesoporous Carbon Single Crystals from Liquefied Wood. Advanced Functional Materials 2023, 42 , 2213852. https://doi.org/10.1002/adfm.202213852
    18. Xincai Wu, Xu Han, Yang Guo, Qian Liu, Ran Sun, Zhaohui Wen, Changsong Dai. Application prospect of calcium peroxide nanoparticles in biomedical field. REVIEWS ON ADVANCED MATERIALS SCIENCE 2023, 62 (1) https://doi.org/10.1515/rams-2022-0308
    19. Yujie Liu, Shilong Liu, Yong Tian, Xiufang Wang. Dual/Triple Template‐Induced Evolved Emulsion for Controllable Construction of Anisotropic Carbon Nanoparticles from Concave to Convex. Advanced Materials 2023, 35 (10) , 2210963. https://doi.org/10.1002/adma.202210963
    20. Kang Xiong, Jinwei Lin, Qiang Chen, Tianyu Gao, Leilei Xu, Jianguo Guan. An axis-asymmetric self-driven micromotor that can perform precession multiplying “on-the-fly” mass transfer. Matter 2023, 6 (3) , 907-924. https://doi.org/10.1016/j.matt.2023.01.005
    21. Qiang Tian, Xiang‐Kang Zeng, Chen Zhao, Ling‐Yan Jing, Xi‐Wang Zhang, Jian Liu. Exceptional Photocatalytic Hydrogen Peroxide Production from Sandwich‐Structured Graphene Interlayered Phenolic Resins Nanosheets with Mesoporous Channels. Advanced Functional Materials 2023, 43 , 2213173. https://doi.org/10.1002/adfm.202213173
    22. Jun Liu, Yingjie Wu, Yue Li, Ling Yang, Hao Wu, Qiang He. Rotary biomolecular motor-powered supramolecular colloidal motor. Science Advances 2023, 9 (8) https://doi.org/10.1126/sciadv.abg3015
    23. Wei Liu, Ya Liu, He Li, Hongmei Nie, Maoye Tian, Wei Long. Biomedical Micro‐/Nanomotors: Design, Imaging, and Disease Treatment. Advanced Functional Materials 2023, 140 , 2212452. https://doi.org/10.1002/adfm.202212452
    24. Yingfei Wang, Wei Chen, Zhong Wang, Yu Zhu, Hongxia Zhao, Kun Wu, Jie Wu, Weihua Zhang, Qing Zhang, Hongqian Guo, Huangxian Ju, Ying Liu. NIR‐II Light Powered Asymmetric Hydrogel Nanomotors for Enhanced Immunochemotherapy. Angewandte Chemie 2023, 135 (3) https://doi.org/10.1002/ange.202212866
    25. Yingfei Wang, Wei Chen, Zhong Wang, Yu Zhu, Hongxia Zhao, Kun Wu, Jie Wu, Weihua Zhang, Qing Zhang, Hongqian Guo, Huangxian Ju, Ying Liu. NIR‐II Light Powered Asymmetric Hydrogel Nanomotors for Enhanced Immunochemotherapy. Angewandte Chemie International Edition 2023, 62 (3) https://doi.org/10.1002/anie.202212866
    26. Jinxin Xie, Yang Zheng, Qizhan Zhang, Shasha Li, Jinyu Gu, Minghua Zhou, Chunhua Wang, Yang Li. Constructing a carbon sphere-embedded Fe0 for accelerating electro-peroxone oxidation effectively: The dual catalytic role with O3 and H2O2. Applied Catalysis B: Environmental 2023, 320 , 121935. https://doi.org/10.1016/j.apcatb.2022.121935
    27. Fuhua Xu, Yanlan Wang, Changlong Wang, Wenkai Huang, Xiang Liu. Dehydrogenation of hydrous hydrazine over carbon nanosphere- supported PtNi nanoparticles for on-demand H2 release. Fuel 2023, 332 , 126116. https://doi.org/10.1016/j.fuel.2022.126116
    28. Pengfei Yang, Yi Chang, Jie Zhang, Fangli Gao, Xinhe Liu, Qingcong Wei, Xiaoming Ma, Yuming Guo. The combination of in situ photodynamic promotion and ion-interference to improve the efficacy of cancer therapy. Journal of Colloid and Interface Science 2023, 629 , 522-533. https://doi.org/10.1016/j.jcis.2022.08.125
    29. Ziyang Song, Ling Miao, Yaokang Lv, Lihua Gan, Mingxian Liu. Versatile carbon superstructures for energy storage. Journal of Materials Chemistry A 2023, 144 https://doi.org/10.1039/D2TA09258A
    30. İshak Afşin Kariper, Ceylan Hepokur, Ferdane Danışman-Kalındemirtaş, Serap Erdem Kuruca. A new method for synthesis of carbon nanoparticle and its applications. Journal of Taibah University for Science 2022, 16 (1) , 966-975. https://doi.org/10.1080/16583655.2022.2131996
    31. Tianyi Liu, Lei Xie, Cameron-Alexander Hurd Price, Jian Liu, Qiang He, Biao Kong. Controlled propulsion of micro/nanomotors: operational mechanisms, motion manipulation and potential biomedical applications. Chemical Society Reviews 2022, 51 (24) , 10083-10119. https://doi.org/10.1039/D2CS00432A
    32. Jinyang Lv, Yi Xing, Xiaoyu Li, Xin Du. NIR light‐propelled bullet‐shaped carbon hollow nanomotors with controllable shell thickness for the enhanced dye removal. Exploration 2022, 2 (6) , 20210162. https://doi.org/10.1002/EXP.20210162
    33. Minghang Qiao, Yi Xing, Lei Xie, Biao Kong, Freddy Kleitz, Xiaoyu Li, Xin Du. Temperature‐Regulated Core Swelling and Asymmetric Shrinkage for Tunable Yolk@Shell Polydopamine@Mesoporous Silica Nanostructures. Small 2022, 18 (52) , 2205576. https://doi.org/10.1002/smll.202205576
    34. W. Song, M. Zhang, X. Huang, B. Chen, Y. Ding, Y. Zhang, D.G. Yu, I. Kim. Smart -borneol-loaded hierarchical hollow polymer nanospheres with antipollution and antibacterial capabilities. Materials Today Chemistry 2022, 26 , 101252. https://doi.org/10.1016/j.mtchem.2022.101252
    35. Yue Wu, Yangyi Sun, Chengyu Zhang, Mengyao He, Dongming Qi. Interfacial-assembly engineering of asymmetric magnetic-mesoporous organosilica nanocomposites with tunable architectures. Nanoscale 2022, 14 (42) , 15772-15788. https://doi.org/10.1039/D2NR03814E
    36. Yijian Tang, Shasha Zheng, Shuai Cao, Feiyu Yang, Xiaotian Guo, Songtao Zhang, Huaiguo Xue, Huan Pang. Hollow mesoporous carbon nanospheres space-confining ultrathin nanosheets superstructures for efficient capacitive deionization. Journal of Colloid and Interface Science 2022, 626 , 1062-1069. https://doi.org/10.1016/j.jcis.2022.07.034
    37. Yunxin Tang, Anuraj Varyambath, Yuanchen Ding, Bailiang Chen, Xinyi Huang, Yu Zhang, Deng-guang Yu, Il Kim, Wenliang Song. Porous organic polymers for drug delivery: hierarchical pore structures, variable morphologies, and biological properties. Biomaterials Science 2022, 10 (19) , 5369-5390. https://doi.org/10.1039/D2BM00719C
    38. Xinyuan Zhou, Xiangyu Chen, Zhenjie Xue, Tie Wang. Nanoparticle assembled structures for matter assays in human flowing systems. Matter 2022, 5 (9) , 2760-2786. https://doi.org/10.1016/j.matt.2022.05.032
    39. Hanfang Feng, Huayang Li, Jin Xu, Yiming Yin, Jinwei Cao, Ruoxin Yu, Bingxue Wang, Runwei Li, Guang Zhu. Triboelectric nanogenerator based on direct image lithography and surface fluorination for biomechanical energy harvesting and self-powered sterilization. Nano Energy 2022, 98 , 107279. https://doi.org/10.1016/j.nanoen.2022.107279
    40. Conghui Liu, Juejiao Huang, Tailin Xu, Xueji Zhang. Powering bioanalytical applications in biomedicine with light-responsive Janus micro-/nanomotors. Microchimica Acta 2022, 189 (3) https://doi.org/10.1007/s00604-022-05229-1
    41. . Guided by the light, nimble nanovehicles make special deliveries. Nature 2022, 487-487. https://doi.org/10.1038/d41586-022-00115-5

    Pair your accounts.

    Export articles to Mendeley

    Get article recommendations from ACS based on references in your Mendeley library.

    Pair your accounts.

    Export articles to Mendeley

    Get article recommendations from ACS based on references in your Mendeley library.

    You’ve supercharged your research process with ACS and Mendeley!

    STEP 1:
    Click to create an ACS ID

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    MENDELEY PAIRING EXPIRED
    Your Mendeley pairing has expired. Please reconnect