Effects of Different Organic Acids on Solubility and Metastable Zone Width of Zinc LactateClick to copy article linkArticle link copied!
Abstract
Effects of three different organic acids including racemic malic acid, succinic acid, and citric acid, which act as an impurity on the solubility and metastable zone width of zinc lactate (ZnL2), have been studied. The results show that the presence of all examined impurities increases the solution solubility and the values of solubility increase with increasing impurity concentration. The introduction of impurity also leads to a reduction on the metastable zone width, and the reductions are pronounced when the impurity concentration increased. Further, experimental data of metastable zone width were analyzed using the expression of the Nývlt’s approach and self-consistent Nývlt-like approach, which can be expressed in the form: ln(ΔTmax/T0) = Φ + β ln b, with intercept Φ = {(1 – m)/m}ln(ΔHd/RTlim) + (1/m)ln(f/KT0) and slope β = 1/m. Here T0 and Tlim are the saturation and nucleation temperature, respectively. m is the apparent nucleation order, and K is a new nucleation constant related to the factor f defined as the number of stable nuclei per unit volume, ΔHd, the heat of dissolution and R the gas constant. Comparing to the former one, the latter approach provides a more satisfactory estimation for the metastable zone width at varying saturation temperature T0. The constant β for specific system reveals independence of the temperature, while the constant Φ increases with increasing saturation temperature. In addition, both constants are proportional to the impurity concentration. Crystal habits of final products are also influenced in the presence of impurities, but the crystal structures are barely changed.
Cited By
This article is cited by 11 publications.
- Shijie Xu, Yixuan Liu, Rong Zhang, Yanfei Wang. How Structurally Similar Additives Affect the Dimensionless Interfacial Tension for Inducing Nucleation: The Case Study of Succinic Acid. Crystal Growth & Design 2024, 24
(1)
, 103-114. https://doi.org/10.1021/acs.cgd.3c00727
- Michael D. Clark, Kenneth R. Morris, and Maria Silvina Tomassone . Correlation of Solubility with the Metastable Limit of Nucleation Using Gauge-Cell Monte Carlo Simulations. Langmuir 2017, 33
(36)
, 9081-9090. https://doi.org/10.1021/acs.langmuir.7b01939
- Kun Zhou, Yueyong Yan, Lianying An, Dongni Xiang, and Hongbin Wang . Solubility, Density, and Metastable Zone Width of Pyridoxine Hydrochloride in Water and Ethanol Solvent Mixtures. Journal of Chemical & Engineering Data 2016, 61
(1)
, 307-312. https://doi.org/10.1021/acs.jced.5b00552
- Yong Ma, Zhou Wang, and Jianying Zhou . Effects of Impurity Ions on the Metastable Zone Width of Phosphoric Acid in Tributyl Phosphate. Journal of Chemical & Engineering Data 2014, 59
(9)
, 2909-2913. https://doi.org/10.1021/je500554c
- Isaac D. Tegladza, Qiaoqiao Liu, Guihong Lin, Jian Zhou, Xuehong Gu, Chang Liu. Effect of trace sodium polystyrene sulfonate on the solubility, nucleation and crystallization of thiourea from metastable zone width data. Journal of Crystal Growth 2022, 598 , 126869. https://doi.org/10.1016/j.jcrysgro.2022.126869
- Xiaolong Sun, Longfei Yin, Huayue Zhu, Junhao Zhu, Jiahuan Hu, Xi Luo, He Huang, Yongqian Fu. Enhanced Antimicrobial Cellulose/Chitosan/ZnO Biodegradable Composite Membrane. Membranes 2022, 12
(2)
, 239. https://doi.org/10.3390/membranes12020239
- Lie-Ding Shiau. A Linear Regression Model for Determining the Pre-Exponential Factor and Interfacial Energy Based on the Metastable Zone Width Data. Crystals 2020, 10
(2)
, 103. https://doi.org/10.3390/cryst10020103
- Daixi Li, Jingtao Cai, Baisong Guo, Dongqing Wei, Qing Liu, Baolin Liu. Controllable crystallization of urea crystal face (0 0 1) by molecular simulation. Journal of Crystal Growth 2019, 524 , 125139. https://doi.org/10.1016/j.jcrysgro.2019.06.025
- Yulan Huang, Jingjing Lu, Honglin Chen, Weiwei Du, Xunqiu Wang. Effects of succinic acid and adipic acid on the metastable width of glutaric acid in acetic acid. Journal of Crystal Growth 2019, 507 , 1-9. https://doi.org/10.1016/j.jcrysgro.2018.10.052
- Xiangyang Zhang, Gang Qian, Xinggui Zhou. Kinetic modeling on batch-cooling crystallization of zinc lactate: The influence of malic acid. Journal of Crystal Growth 2017, 463 , 162-167. https://doi.org/10.1016/j.jcrysgro.2017.02.023
- Ye Yuan, Yixin Leng, Chunxiang Huang, Mingxuan Yue, Qian Tan. Effects of cooling rate, saturation temperature, and agitation on the metastable zone width of DL-malic acid-water system. Russian Journal of Physical Chemistry A 2015, 89
(9)
, 1567-1571. https://doi.org/10.1134/S0036024415090381
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.
Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.
The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated.