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Solubility of Lovastatin in Acetone + Water Solvent Mixtures

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School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People’s Republic of China
* To whom correspondence should be addressed. E-mail: [email protected]. Fax: 86-22-27374971.
Cite this: J. Chem. Eng. Data 2008, 53, 6, 1335–1337
Publication Date (Web):May 3, 2008
https://doi.org/10.1021/je800063d
Copyright © 2008 American Chemical Society

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    Abstract

    The solubilities of lovastatin in binary acetone + water solvent mixtures were determined by the synthetic method from (277.35 to 310.05) K by a laser monitoring observation technique. Results of these measurements were correlated by the semiempirical equation. For the nine mole fractions of acetone studied, a semiempirical equation was found to provide an accurate mathematical representation of the experimental data.

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    10. Jie-Ping Fan, Tao Kong, Xue-Hong Zhang, Lu Zhang, Sheng Tong, Zhe-You Tian, Jian-Hang Zhu. Solubilities of oleanolic acid and ursolic acid in (ethanol+water) mixed solvents from T=(292.2 to 328.2)K. The Journal of Chemical Thermodynamics 2012, 47 , 372-375. https://doi.org/10.1016/j.jct.2011.11.017
    11. Hua Sun, Jingkang Wang, Junbo Gong. Determination of nucleation kinetics of lovastatin in acetone solution. Crystal Research and Technology 2010, 45 (7) , 707-711. https://doi.org/10.1002/crat.201000060
    12. . Solubility Data in Binary Solvent Mixtures. 2009, 203-505. https://doi.org/10.1201/9781439804889-c3

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