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Solubility of Clindamycin Phosphate in Methanol, Ethanol, and Dimethyl Sulfoxide

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School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, P. R. China
* Corresponding author. E-mail: [email protected]
Cite this: J. Chem. Eng. Data 2008, 53, 8, 1984–1985
Publication Date (Web):July 23, 2008
https://doi.org/10.1021/je800291t
Copyright © 2008 American Chemical Society

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    Abstract

    The solubilities of clindamycin phosphate in different solvents (methanol, ethanol, and dimethyl sulfoxide) were measured at temperatures from (283.15 to 333.15) K by a synthetic method at atmospheric pressure. The experimental data were correlated with the modified Apelblat equation. The equation was found to provide an accurate representation of the experimental data. The dissolution enthalpy determined from the experimental solubility data was also presented.

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    Cited By

    This article is cited by 5 publications.

    1. Yuanyuan Ran, Weibing Dong, Songgu Wu, Jingkang Wang, and Junbo Gong . Transformations among the New Solid-State Forms of Clindamycin Phosphate. Organic Process Research & Development 2013, 17 (11) , 1445-1450. https://doi.org/10.1021/op400232v
    2. Pingping Jiang and Zhanzhong Wang. Solubility of p-Aminobenzenesulfonamide in Different Solvents from (283.15 to 323.15) K. Journal of Chemical & Engineering Data 2009, 54 (6) , 1945-1946. https://doi.org/10.1021/je900038m
    3. Xian-Rui Liang, Chun-Xia Si, Fei-Yan Chen, Wei-Ke Su and Xiao-Na Yu. Solubility of Tiamulin Hydrogen Fumarate in Acetone, Acetonitrile, Ethyl Acetate, Ethyl Formate, and Butyl Acetate from (288.2 to 318.2) K. Journal of Chemical & Engineering Data 2009, 54 (3) , 1126-1128. https://doi.org/10.1021/je800838w
    4. Marija Vukomanović, Srečo Davor Škapin, Boštjan Jančar, Tatjana Maksin, Nenad Ignjatović, Vuk Uskoković, Dragan Uskoković. Poly(d,l-lactide-co-glycolide)/hydroxyapatite core-shell nanospheres. Part 1: A multifunctional system for controlled drug delivery. Colloids and Surfaces B: Biointerfaces 2011, 82 (2) , 404-413. https://doi.org/10.1016/j.colsurfb.2010.09.011
    5. . Solubility Data in Organic Solvents. 2009, 69-202. https://doi.org/10.1201/9781439804889-c2

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