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Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum)

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    Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum)
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    Department of Bioscicence and Biotechnology, Faculty of Agriculture, University of the Ryukyus, Okinawa 903-0123, Japan
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    Journal of Agricultural and Food Chemistry

    Cite this: J. Agric. Food Chem. 2006, 54, 3, 720–725
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    https://doi.org/10.1021/jf0519461
    Published January 13, 2006
    Copyright © 2006 American Chemical Society
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    Abstract

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    This is the first report showing that kava lactones are plant and plant fungus growth inhibitors. Aqueous extract of kava roots showed high allelopathic potential and strongly suppressed germination and growth of lettuce, radish, barnyardgrass, and monochoria. Nine kava lactones were detected using GC-MS including desmethoxyyagonin, kavain, 7,8-dihydrokavain, hydroxykavain, yagonin, 5,6,7,8-tetrahydroxyyagonin, methysticin, dihydromethysticin, and 11-hydroxy-12-methoxydihydrokavain. Quantities of desmethoxyyagonin, kavain, 7,8-dihydrokavain, yagonin, methysticin, and dihydromethysticin detected were 4.3, 6.9, 18.6, 5.7, 1.4, and 5.4 mg/g of dry weight, respectively. These six major lactones in kava roots showed great herbicidal and antifungal activities. Growth of lettuce and barnyardgrass were significantly inhibited at 1−10 ppm, and four plant fungi including Colletotrichum gloeosporides, Fusarium solani, Fusarium oxysporum, and Trichoderma viride were significantly inhibited at 10−50 ppm. The biological activities of kava lactones were characterized by different double-bond linkage patterns in positions 5,6 and 7,8. The findings of this study suggest that kava lactones may be useful for the development of bioactive herbicides and fungicides.

    Keywords: Fungicide; herbicide; inhibition; kava roots; kava lactones; plant fungi; weeds

    Copyright © 2006 American Chemical Society

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    Journal of Agricultural and Food Chemistry

    Cite this: J. Agric. Food Chem. 2006, 54, 3, 720–725
    Click to copy citationCitation copied!
    https://doi.org/10.1021/jf0519461
    Published January 13, 2006
    Copyright © 2006 American Chemical Society
    Request reuse permissions

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